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Prostate Myeloid Sarcoma

MedGen UID:
235501
•Concept ID:
C1335514
•
Neoplastic Process
Synonyms: Extramedullary Myeloid Neoplasm of Prostate; Extramedullary Myeloid Neoplasm of the Prostate; Extramedullary Myeloid Tumor of Prostate; Extramedullary Myeloid Tumor of the Prostate; Prostate Extramedullary Myeloid Neoplasm; Prostate Extramedullary Myeloid Tumor; Prostatic Chloroma; Prostatic Extramedullary Myeloid Neoplasm; Prostatic Extramedullary Myeloid Tumor; Prostatic Myeloid Sarcoma

Definition

Myeloid sarcoma that affects the prostate gland. It may present in association with or as a site of relapse of acute myeloid leukemia. Cases of myeloid sarcoma of the prostate gland preceding acute myeloid leukemia have also been reported. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVProstate Myeloid Sarcoma

Professional guidelines

PubMed

APOBEC3C is a novel target for the immune treatment of lower-grade gliomas.
Zhao S, Li Y, Xu J, Shen L
Neurol Res 2024 Mar;46(3):227-242. Epub 2024 Jan 22 doi: 10.1080/01616412.2023.2287340. PMID: 38007705

Recent clinical studies

Etiology

Antitumor Profile of Carbon-Bridged Steroids (CBS) and Triterpenoids.
Dembitsky VM, Gloriozova TA, Poroikov VV
Mar Drugs 2021 Jun 3;19(6) doi: 10.3390/md19060324. PMID: 34205074Free PMC Article
B-cell acute lymphoblastic leukemia in an elderly man with plasma cell myeloma and long-term exposure to thalidomide and lenalidomide: a case report and literature review.
Sinit RB, Hwang DG, Vishnu P, Peterson JF, Aboulafia DM
BMC Cancer 2019 Nov 27;19(1):1147. doi: 10.1186/s12885-019-6286-9. PMID: 31775673Free PMC Article
A Five-year Survey of Cancer Prevalence in Sudan.
Saeed ME, Cao J, Fadul B, Kadioglu O, Khalid HE, Yassin Z, Mustafa SM, Saeed E, Efferth T
Anticancer Res 2016 Jan;36(1):279-86. PMID: 26722054
Molecular pathways: the role of NR4A orphan nuclear receptors in cancer.
Mohan HM, Aherne CM, Rogers AC, Baird AW, Winter DC, Murphy EP
Clin Cancer Res 2012 Jun 15;18(12):3223-8. Epub 2012 May 7 doi: 10.1158/1078-0432.CCR-11-2953. PMID: 22566377
Second cancers in patients with male breast cancer: a literature review.
Grenader T, Goldberg A, Shavit L
J Cancer Surviv 2008 Jun;2(2):73-8. Epub 2008 Apr 1 doi: 10.1007/s11764-008-0042-5. PMID: 18648975

Diagnosis

APOBEC3C is a novel target for the immune treatment of lower-grade gliomas.
Zhao S, Li Y, Xu J, Shen L
Neurol Res 2024 Mar;46(3):227-242. Epub 2024 Jan 22 doi: 10.1080/01616412.2023.2287340. PMID: 38007705
Very late extramedullary relapse of acute myeloid leukaemia as prostatic myeloid sarcoma occurring 24 years post-allograft.
Taylor T, Byrne J, Errico G, Clark D
Br J Haematol 2022 May;197(3):243. Epub 2022 Feb 22 doi: 10.1111/bjh.18038. PMID: 35191543
B-cell acute lymphoblastic leukemia in an elderly man with plasma cell myeloma and long-term exposure to thalidomide and lenalidomide: a case report and literature review.
Sinit RB, Hwang DG, Vishnu P, Peterson JF, Aboulafia DM
BMC Cancer 2019 Nov 27;19(1):1147. doi: 10.1186/s12885-019-6286-9. PMID: 31775673Free PMC Article
A Five-year Survey of Cancer Prevalence in Sudan.
Saeed ME, Cao J, Fadul B, Kadioglu O, Khalid HE, Yassin Z, Mustafa SM, Saeed E, Efferth T
Anticancer Res 2016 Jan;36(1):279-86. PMID: 26722054
Second cancers in patients with male breast cancer: a literature review.
Grenader T, Goldberg A, Shavit L
J Cancer Surviv 2008 Jun;2(2):73-8. Epub 2008 Apr 1 doi: 10.1007/s11764-008-0042-5. PMID: 18648975

Therapy

B-cell acute lymphoblastic leukemia in an elderly man with plasma cell myeloma and long-term exposure to thalidomide and lenalidomide: a case report and literature review.
Sinit RB, Hwang DG, Vishnu P, Peterson JF, Aboulafia DM
BMC Cancer 2019 Nov 27;19(1):1147. doi: 10.1186/s12885-019-6286-9. PMID: 31775673Free PMC Article
Myeloid sarcoma of the prostate as first clinical manifestation of acute myeloid leukaemia.
Spethmann S, Heuer R, Hopfer H, Tuinmann G
Lancet Oncol 2004 Jan;5(1):62-3. doi: 10.1016/s1470-2045(03)01326-3. PMID: 14700611
Thalidomide: a review of approved and investigational uses.
Matthews SJ, McCoy C
Clin Ther 2003 Feb;25(2):342-95. doi: 10.1016/s0149-2918(03)80085-1. PMID: 12749503
Second malignancies as a consequence of nucleoside analog therapy for chronic lymphoid leukemias.
Cheson BD, Vena DA, Barrett J, Freidlin B
J Clin Oncol 1999 Aug;17(8):2454-60. doi: 10.1200/JCO.1999.17.8.2454. PMID: 10561309
Mortality among plutonium and other radiation workers at a plutonium weapons facility.
Wilkinson GS, Tietjen GL, Wiggs LD, Galke WA, Acquavella JF, Reyes M, Voelz GL, Waxweiler RJ
Am J Epidemiol 1987 Feb;125(2):231-50. doi: 10.1093/oxfordjournals.aje.a114523. PMID: 3812431

Prognosis

APOBEC3C is a novel target for the immune treatment of lower-grade gliomas.
Zhao S, Li Y, Xu J, Shen L
Neurol Res 2024 Mar;46(3):227-242. Epub 2024 Jan 22 doi: 10.1080/01616412.2023.2287340. PMID: 38007705
Prognostic and clinical significance of long non-coding RNA SNHG12 expression in various cancers.
Zhang C, Ren X, Zhang W, He L, Qi L, Chen R, Tu C, Li Z
Bioengineered 2020 Dec;11(1):1112-1123. doi: 10.1080/21655979.2020.1831361. PMID: 33124951Free PMC Article
Advancing Pan-cancer Gene Expression Survial Analysis by Inclusion of Non-coding RNA.
Ye B, Shi J, Kang H, Oyebamiji O, Hill D, Yu H, Ness S, Ye F, Ping J, He J, Edwards J, Zhao YY, Guo Y
RNA Biol 2020 Nov;17(11):1666-1673. Epub 2019 Oct 18 doi: 10.1080/15476286.2019.1679585. PMID: 31607216Free PMC Article
B-cell acute lymphoblastic leukemia in an elderly man with plasma cell myeloma and long-term exposure to thalidomide and lenalidomide: a case report and literature review.
Sinit RB, Hwang DG, Vishnu P, Peterson JF, Aboulafia DM
BMC Cancer 2019 Nov 27;19(1):1147. doi: 10.1186/s12885-019-6286-9. PMID: 31775673Free PMC Article
ERG is a megakaryocytic oncogene.
Salek-Ardakani S, Smooha G, de Boer J, Sebire NJ, Morrow M, Rainis L, Lee S, Williams O, Izraeli S, Brady HJ
Cancer Res 2009 Jun 1;69(11):4665-73. doi: 10.1158/0008-5472.CAN-09-0075. PMID: 19487285

Clinical prediction guides

APOBEC3C is a novel target for the immune treatment of lower-grade gliomas.
Zhao S, Li Y, Xu J, Shen L
Neurol Res 2024 Mar;46(3):227-242. Epub 2024 Jan 22 doi: 10.1080/01616412.2023.2287340. PMID: 38007705
Advancing Pan-cancer Gene Expression Survial Analysis by Inclusion of Non-coding RNA.
Ye B, Shi J, Kang H, Oyebamiji O, Hill D, Yu H, Ness S, Ye F, Ping J, He J, Edwards J, Zhao YY, Guo Y
RNA Biol 2020 Nov;17(11):1666-1673. Epub 2019 Oct 18 doi: 10.1080/15476286.2019.1679585. PMID: 31607216Free PMC Article
ERG is a megakaryocytic oncogene.
Salek-Ardakani S, Smooha G, de Boer J, Sebire NJ, Morrow M, Rainis L, Lee S, Williams O, Izraeli S, Brady HJ
Cancer Res 2009 Jun 1;69(11):4665-73. doi: 10.1158/0008-5472.CAN-09-0075. PMID: 19487285
Mortality among plutonium and other radiation workers at a plutonium weapons facility.
Wilkinson GS, Tietjen GL, Wiggs LD, Galke WA, Acquavella JF, Reyes M, Voelz GL, Waxweiler RJ
Am J Epidemiol 1987 Feb;125(2):231-50. doi: 10.1093/oxfordjournals.aje.a114523. PMID: 3812431
Spirogermanium: a new investigational drug of novel structure and lack of bone marrow toxicity.
Slavik M, Blanc O, Davis J
Invest New Drugs 1983;1(3):225-34. doi: 10.1007/BF00208894. PMID: 6678870

Recent systematic reviews

Second cancers in patients with male breast cancer: a literature review.
Grenader T, Goldberg A, Shavit L
J Cancer Surviv 2008 Jun;2(2):73-8. Epub 2008 Apr 1 doi: 10.1007/s11764-008-0042-5. PMID: 18648975

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