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Male reproductive organ cancer

MedGen UID:
102279
Concept ID:
C0153606
Neoplastic Process
Synonyms: cancer of male reproductive organ; male genital cancer; male reproductive organ cancer; malignant male reproductive organ neoplasm; Malignant Male Reproductive System Neoplasm; malignant Male reproductive system neoplasm; Malignant Male Reproductive System Tumor; malignant Male reproductive system tumor; malignant Male reproductive system tumour; malignant neoplasm of male genital organ; malignant neoplasm of male genital organ or tract; malignant neoplasm of male genital organ, site unspecified; malignant neoplasm of male genital organs; malignant neoplasm of male reproductive organ; Malignant Neoplasm of Male Reproductive System; malignant neoplasm of Male reproductive system; Malignant Neoplasm of the Male Reproductive System; malignant neoplasm of the Male reproductive system; Malignant tumor of male genital organ; malignant tumor of male genital organ; Malignant Tumor of Male Reproductive System; malignant tumor of Male reproductive system; malignant tumor of male reproductive system; Malignant Tumor of the Male Reproductive System; malignant tumor of the Male reproductive system; malignant tumour of male genital organ; malignant tumour of male reproductive system; malignant tumour of Male reproductive system; malignant tumour of the Male reproductive system
SNOMED CT: Malignant tumor of male genital organ (363515000)
 
Monarch Initiative: MONDO:0005836

Definition

A primary or metastatic malignant neoplasm involving the male reproductive system. Representative examples include prostate carcinoma, penile carcinoma, testicular seminoma, and testicular embryonal carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMale reproductive organ cancer

Professional guidelines

PubMed

Williams IS, McVey A, Perera S, O'Brien JS, Kostos L, Chen K, Siva S, Azad AA, Murphy DG, Kasivisvanathan V, Lawrentschuk N, Frydenberg M
Med J Aust 2022 Oct 17;217(8):424-433. Epub 2022 Oct 2 doi: 10.5694/mja2.51722. PMID: 36183329Free PMC Article
Hembree WC, Cohen-Kettenis PT, Gooren L, Hannema SE, Meyer WJ, Murad MH, Rosenthal SM, Safer JD, Tangpricha V, T'Sjoen GG
J Clin Endocrinol Metab 2017 Nov 1;102(11):3869-3903. doi: 10.1210/jc.2017-01658. PMID: 28945902
Litwin MS, Tan HJ
JAMA 2017 Jun 27;317(24):2532-2542. doi: 10.1001/jama.2017.7248. PMID: 28655021

Recent clinical studies

Etiology

Mohanty SK, Lobo A, Cheng L
Hum Pathol 2023 Jun;136:123-143. Epub 2022 Sep 6 doi: 10.1016/j.humpath.2022.08.006. PMID: 36084769
Langan RC, Puente MEE
Am Fam Physician 2022 Aug;106(2):184-189. PMID: 35977130
Rives N, Courbière B, Almont T, Kassab D, Berger C, Grynberg M, Papaxanthos A, Decanter C, Elefant E, Dhedin N, Barraud-Lange V, Béranger MC, Demoor-Goldschmidt C, Frédérique N, Bergère M, Gabrel L, Duperray M, Vermel C, Hoog-Labouret N, Pibarot M, Provansal M, Quéro L, Lejeune H, Methorst C, Saias J, Véronique-Baudin J, Giscard d'Estaing S, Farsi F, Poirot C, Huyghe É
Eur J Cancer 2022 Sep;173:146-166. Epub 2022 Aug 3 doi: 10.1016/j.ejca.2022.05.013. PMID: 35932626
Moch H, Amin MB, Berney DM, Compérat EM, Gill AJ, Hartmann A, Menon S, Raspollini MR, Rubin MA, Srigley JR, Hoon Tan P, Tickoo SK, Tsuzuki T, Turajlic S, Cree I, Netto GJ
Eur Urol 2022 Nov;82(5):458-468. Epub 2022 Jul 16 doi: 10.1016/j.eururo.2022.06.016. PMID: 35853783
Markowski MC, Boorjian SA, Burton JP, Hahn NM, Ingersoll MA, Maleki Vareki S, Pal SK, Sfanos KS
Eur Urol 2019 Apr;75(4):637-646. Epub 2019 Jan 15 doi: 10.1016/j.eururo.2018.12.043. PMID: 30655087Free PMC Article

Diagnosis

Bendarska-Czerwińska A, Zmarzły N, Morawiec E, Panfil A, Bryś K, Czarniecka J, Ostenda A, Dziobek K, Sagan D, Boroń D, Michalski P, Pallazo-Michalska V, Grabarek BO
Front Endocrinol (Lausanne) 2022;13:970439. Epub 2023 Jan 17 doi: 10.3389/fendo.2022.970439. PMID: 36733805Free PMC Article
Langan RC, Puente MEE
Am Fam Physician 2022 Aug;106(2):184-189. PMID: 35977130
Moch H, Amin MB, Berney DM, Compérat EM, Gill AJ, Hartmann A, Menon S, Raspollini MR, Rubin MA, Srigley JR, Hoon Tan P, Tickoo SK, Tsuzuki T, Turajlic S, Cree I, Netto GJ
Eur Urol 2022 Nov;82(5):458-468. Epub 2022 Jul 16 doi: 10.1016/j.eururo.2022.06.016. PMID: 35853783
Zarei A, Javid H, Sanjarian S, Senemar S, Zarei H
Prostate 2022 Feb;82(3):289-297. Epub 2021 Dec 2 doi: 10.1002/pros.24276. PMID: 34855234
Dauendorffer JN, Herms F, Baroudjian B, Basset-Seguin N, Cavelier-Balloy B, Fouéré S, Bagot M, Lebbé C
Ann Dermatol Venereol 2021 Jun;148(2):71-76. Epub 2021 Jan 16 doi: 10.1016/j.annder.2020.08.051. PMID: 33461789

Therapy

Tang C, Sherry AD, Haymaker C, Bathala T, Liu S, Fellman B, Cohen L, Aparicio A, Zurita AJ, Reuben A, Marmonti E, Chun SG, Reddy JP, Ghia A, McGuire S, Efstathiou E, Wang J, Wang J, Pilie P, Kovitz C, Du W, Simiele SJ, Kumar R, Borghero Y, Shi Z, Chapin B, Gomez D, Wistuba I, Corn PG
JAMA Oncol 2023 Jun 1;9(6):825-834. doi: 10.1001/jamaoncol.2023.0161. PMID: 37022702Free PMC Article
Swami U, McFarland TR, Nussenzveig R, Agarwal N
Trends Cancer 2020 Aug;6(8):702-715. Epub 2020 Jun 10 doi: 10.1016/j.trecan.2020.04.010. PMID: 32534790
Del-Pozo-Lérida S, Salvador C, Martínez-Soler F, Tortosa A, Perucho M, Giménez-Bonafé P
Oncol Rep 2019 May;41(5):2607-2614. Epub 2019 Mar 14 doi: 10.3892/or.2019.7063. PMID: 30896846
Kasivisvanathan V, Rannikko AS, Borghi M, Panebianco V, Mynderse LA, Vaarala MH, Briganti A, Budäus L, Hellawell G, Hindley RG, Roobol MJ, Eggener S, Ghei M, Villers A, Bladou F, Villeirs GM, Virdi J, Boxler S, Robert G, Singh PB, Venderink W, Hadaschik BA, Ruffion A, Hu JC, Margolis D, Crouzet S, Klotz L, Taneja SS, Pinto P, Gill I, Allen C, Giganti F, Freeman A, Morris S, Punwani S, Williams NR, Brew-Graves C, Deeks J, Takwoingi Y, Emberton M, Moore CM; PRECISION Study Group Collaborators
N Engl J Med 2018 May 10;378(19):1767-1777. Epub 2018 Mar 18 doi: 10.1056/NEJMoa1801993. PMID: 29552975Free PMC Article
Jagasia MH, Greinix HT, Arora M, Williams KM, Wolff D, Cowen EW, Palmer J, Weisdorf D, Treister NS, Cheng GS, Kerr H, Stratton P, Duarte RF, McDonald GB, Inamoto Y, Vigorito A, Arai S, Datiles MB, Jacobsohn D, Heller T, Kitko CL, Mitchell SA, Martin PJ, Shulman H, Wu RS, Cutler CS, Vogelsang GB, Lee SJ, Pavletic SZ, Flowers ME
Biol Blood Marrow Transplant 2015 Mar;21(3):389-401.e1. Epub 2014 Dec 18 doi: 10.1016/j.bbmt.2014.12.001. PMID: 25529383Free PMC Article

Prognosis

D'Ecclesiis O, Pastore E, Gandini S, Caini S, Marvaso G, Jereczek-Fossa BA, Corrao G, Raimondi S, Bellerba F, Ciceri S, Latella M, Cavalcabò NB, Bendinelli B, Saieva C, Fontana M, Gnagnarella P
Nutrients 2023 Feb 12;15(4) doi: 10.3390/nu15040925. PMID: 36839283Free PMC Article
Zimmerman HJN
J Registry Manag 2022 Winter;49(4):190-193. PMID: 37260820Free PMC Article
Kensler KH, Rebbeck TR
Cancer Epidemiol Biomarkers Prev 2020 Feb;29(2):267-277. doi: 10.1158/1055-9965.EPI-19-0412. PMID: 32024765Free PMC Article
Stevenson SM, Lowrance WT
Urol Clin North Am 2015 Aug;42(3):269-75. Epub 2015 Jun 11 doi: 10.1016/j.ucl.2015.04.001. PMID: 26216814
Hutson JM, Balic A, Nation T, Southwell B
Semin Pediatr Surg 2010 Aug;19(3):215-24. doi: 10.1053/j.sempedsurg.2010.04.001. PMID: 20610195

Clinical prediction guides

Annamalai A, Fustok JN, Beltran-Perez J, Rashad AT, Krane LS, Triche BL
Curr Urol Rep 2022 Jan;23(1):1-10. Epub 2022 Feb 28 doi: 10.1007/s11934-022-01084-y. PMID: 35226257
Broncy L, Paterlini-Bréchot P
Cells 2019 Jul 3;8(7) doi: 10.3390/cells8070676. PMID: 31277346Free PMC Article
Oliveira PF, Martins AD, Moreira AC, Cheng CY, Alves MG
Med Res Rev 2015 Jan;35(1):126-51. Epub 2014 Jul 12 doi: 10.1002/med.21325. PMID: 25043918Free PMC Article
Bjurlin MA, Taneja SS
Curr Opin Urol 2014 Mar;24(2):155-61. doi: 10.1097/MOU.0000000000000031. PMID: 24451092Free PMC Article
Dere E, Anderson LM, Hwang K, Boekelheide K
Fertil Steril 2013 Nov;100(5):1192-202. doi: 10.1016/j.fertnstert.2013.09.017. PMID: 24182554Free PMC Article

Recent systematic reviews

Bergengren O, Pekala KR, Matsoukas K, Fainberg J, Mungovan SF, Bratt O, Bray F, Brawley O, Luckenbaugh AN, Mucci L, Morgan TM, Carlsson SV
Eur Urol 2023 Aug;84(2):191-206. Epub 2023 May 16 doi: 10.1016/j.eururo.2023.04.021. PMID: 37202314Free PMC Article
Chow KM, So WZ, Lee HJ, Lee A, Yap DWT, Takwoingi Y, Tay KJ, Tuan J, Thang SP, Lam W, Yuen J, Lawrentschuk N, Hofman MS, Murphy DG, Chen K
Eur Urol 2023 Jul;84(1):36-48. Epub 2023 Apr 7 doi: 10.1016/j.eururo.2023.03.001. PMID: 37032189
Sciacqua LV, Vanzulli A, Di Meo R, Pellegrino G, Lavorato R, Vitale G, Carrafiello G
Technol Cancer Res Treat 2023 Jan-Dec;22:15330338231155000. doi: 10.1177/15330338231155000. PMID: 36794408Free PMC Article
Boroujeni SN, Malamiri FA, Bossaghzadeh F, Esmaeili A, Moudi E
JBRA Assist Reprod 2022 Aug 4;26(3):522-530. doi: 10.5935/1518-0557.20210108. PMID: 35234023Free PMC Article
Gunes S, Hekim GN, Arslan MA, Asci R
J Assist Reprod Genet 2016 Apr;33(4):441-54. Epub 2016 Feb 11 doi: 10.1007/s10815-016-0663-y. PMID: 26867640Free PMC Article

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