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Urethra leiomyoma

MedGen UID:
237035
•Concept ID:
C1336888
•
Neoplastic Process
Synonyms: Leiomyoma of the Urethra; leiomyoma of the urethra; Leiomyoma of Urethra; leiomyoma of urethra; Urethra Leiomyoma; urethra leiomyoma; Urethral Leiomyoma; urethral leiomyoma
 
Monarch Initiative: MONDO:0002222

Definition

A benign smooth muscle neoplasm arising from the urethra. It is characterized by the presence of spindle cells with cigar-shaped nuclei, interlacing fascicles, and a whorled pattern. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUrethra leiomyoma

Professional guidelines

PubMed

Management of abnormal genital bleeding in girls and women.
Cowan BD, Morrison JC
N Engl J Med 1991 Jun 13;324(24):1710-5. doi: 10.1056/NEJM199106133242406. PMID: 2034248

Recent clinical studies

Etiology

Computed tomography and magnetic resonance imaging findings in dogs with vaginal leiomyoma and leiomyosarcoma.
Tanaka T, Noguchi S, Wada Y, Yamazaki H, Nishida H, Akiyoshi H
Vet Med Sci 2022 Nov;8(6):2337-2344. Epub 2022 Sep 5 doi: 10.1002/vms3.930. PMID: 36063539Free PMC Article
The ultrasonographic characteristics of female periurethral solid masses.
Wang X, Lei J, Zhang W, Zhou J, Song L, Ying T
Int Urogynecol J 2022 Mar;33(3):605-612. Epub 2022 Jan 10 doi: 10.1007/s00192-021-05022-3. PMID: 35006310
Evaluating ureteral patency in the post-indigo carmine era: a randomized controlled trial.
Grimes CL, Patankar S, Ryntz T, Philip N, Simpson K, Truong M, Young C, Advincula A, Madueke-Laveaux OS, Walters R, Ananth CV, Kim JH
Am J Obstet Gynecol 2017 Nov;217(5):601.e1-601.e10. Epub 2017 Jul 18 doi: 10.1016/j.ajog.2017.07.012. PMID: 28729014
Leiomyoma of the urethra and bladder.
Goldman HB, McAchran SE, MacLennan GT
J Urol 2007 May;177(5):1890. doi: 10.1016/j.juro.2007.02.017. PMID: 17437842
Leiomyomas of the female urethra and bladder: a report of five cases and review of the literature.
Bai SW, Jung HJ, Jeon MJ, Jung DJ, Kim SK, Kim JW
Int Urogynecol J Pelvic Floor Dysfunct 2007 Aug;18(8):913-7. Epub 2007 Mar 1 doi: 10.1007/s00192-006-0257-9. PMID: 17333443

Diagnosis

The ultrasonographic characteristics of female periurethral solid masses.
Wang X, Lei J, Zhang W, Zhou J, Song L, Ying T
Int Urogynecol J 2022 Mar;33(3):605-612. Epub 2022 Jan 10 doi: 10.1007/s00192-021-05022-3. PMID: 35006310
Robotic resection of a large ovarian leiomyoma.
Mangano A, Valle V, Bustos R, Gruessner S, Masrur M, Aguiluz G, Bianco F, Giulianotti PC
Minerva Chir 2020 Apr;75(2):121-124. doi: 10.23736/S0026-4733.20.08253-X. PMID: 32267137
Urological complications of uterine leiomyoma: a review of literature.
Dagur G, Suh Y, Warren K, Singh N, Fitzgerald J, Khan SA
Int Urol Nephrol 2016 Jun;48(6):941-8. Epub 2016 Feb 27 doi: 10.1007/s11255-016-1248-5. PMID: 26922066
Leiomyoma of the urethra and bladder.
Goldman HB, McAchran SE, MacLennan GT
J Urol 2007 May;177(5):1890. doi: 10.1016/j.juro.2007.02.017. PMID: 17437842
Paraurethral leiomyoma--an imitator.
Cattolica EV, Klein R, Knigge W
Urology 1976 Dec;8(6):605-7. doi: 10.1016/0090-4295(76)90532-x. PMID: 825997

Therapy

Evaluating ureteral patency in the post-indigo carmine era: a randomized controlled trial.
Grimes CL, Patankar S, Ryntz T, Philip N, Simpson K, Truong M, Young C, Advincula A, Madueke-Laveaux OS, Walters R, Ananth CV, Kim JH
Am J Obstet Gynecol 2017 Nov;217(5):601.e1-601.e10. Epub 2017 Jul 18 doi: 10.1016/j.ajog.2017.07.012. PMID: 28729014
Management of symptomatic urethral diverticula in women: a single-centre experience.
Reeves FA, Inman RD, Chapple CR
Eur Urol 2014 Jul;66(1):164-72. Epub 2014 Feb 26 doi: 10.1016/j.eururo.2014.02.041. PMID: 24636677
Lower urinary tract injury in women in the United States, 1979-2006.
Frankman EA, Wang L, Bunker CH, Lowder JL
Am J Obstet Gynecol 2010 May;202(5):495.e1-5. Epub 2010 Mar 12 doi: 10.1016/j.ajog.2010.01.013. PMID: 20223442Free PMC Article
Urethral and paraurethral leiomyomas in the female patient.
Ozel B, Ballard C
Int Urogynecol J Pelvic Floor Dysfunct 2006 Jan;17(1):93-5. Epub 2005 May 19 doi: 10.1007/s00192-005-1316-3. PMID: 15905997
Renal leiomyoma associated with Epstein-Barr virus in a pediatric transplant patient.
Dionne JM, Carter JE, Matsell D, MacNeily AE, Morrison KB, de Sa D
Am J Kidney Dis 2005 Aug;46(2):351-5. doi: 10.1053/j.ajkd.2005.04.028. PMID: 16112056

Prognosis

Lower urinary tract injury in women in the United States, 1979-2006.
Frankman EA, Wang L, Bunker CH, Lowder JL
Am J Obstet Gynecol 2010 May;202(5):495.e1-5. Epub 2010 Mar 12 doi: 10.1016/j.ajog.2010.01.013. PMID: 20223442Free PMC Article
Leiomyoma of the male urethra: case report and review of the literature.
Garrido Abad P, Fernández Arjona M, Herranz Fernández LM, Muñoz-Delgado Salmerón J, Capote LF
Arch Esp Urol 2010 Jan-Feb;63(1):71-4. PMID: 20157222
Leiomyoma of the urethra and bladder.
Goldman HB, McAchran SE, MacLennan GT
J Urol 2007 May;177(5):1890. doi: 10.1016/j.juro.2007.02.017. PMID: 17437842
Leiomyoma of the female urethra with upper tract dilation and treatment with transurethral resection: a case report and literature review.
Joshi HB, Beck RO
Tech Urol 2000 Sep;6(3):223-5. PMID: 10963495
Angiomyofibroblastoma of the female urethra.
Kitamura H, Miyao N, Sato Y, Matsukawa M, Tsukamoto T, Sato T
Int J Urol 1999 May;6(5):268-70. doi: 10.1046/j.1442-2042.1999.00059.x. PMID: 10375192

Clinical prediction guides

A urethral leiomyoma presenting with dysuria: A rare case report.
Wu S, Min Z, Wu L, Zhang M, Wu L
Medicine (Baltimore) 2024 May 17;103(20):e37893. doi: 10.1097/MD.0000000000037893. PMID: 38758882Free PMC Article
Transvaginal excision of vaginal paraurethral leiomyoma: A video case report.
Costa C, Barba M, Cola A, Frigerio M
Eur J Obstet Gynecol Reprod Biol 2023 Nov;290:11-13. Epub 2023 Sep 11 doi: 10.1016/j.ejogrb.2023.09.008. PMID: 37708657
Evaluating ureteral patency in the post-indigo carmine era: a randomized controlled trial.
Grimes CL, Patankar S, Ryntz T, Philip N, Simpson K, Truong M, Young C, Advincula A, Madueke-Laveaux OS, Walters R, Ananth CV, Kim JH
Am J Obstet Gynecol 2017 Nov;217(5):601.e1-601.e10. Epub 2017 Jul 18 doi: 10.1016/j.ajog.2017.07.012. PMID: 28729014
Female paraurethral leiomyoma: ultrasonographic and magnetic resonance imaging findings.
Pavlica P, Bartolone A, Gaudiano C, Barozzi L
Acta Radiol 2004 Nov;45(7):796-8. doi: 10.1080/02841850410001376. PMID: 15624526
Leiomyoma of the female urethra and bladder: report of twenty-three patients and review of the literature.
Cornella JL, Larson TR, Lee RA, Magrina JF, Kammerer-Doak D
Am J Obstet Gynecol 1997 Jun;176(6):1278-85. doi: 10.1016/s0002-9378(97)70346-6. PMID: 9215185

Recent systematic reviews

What is this vaginal bulge? An atypical case of vaginal paraurethral leiomyoma. A case report and literature systematic review.
Braga A, Soave I, Caccia G, Regusci L, Ruggeri G, Pitaku I, Bassi V, Papadia A, Serati M
J Gynecol Obstet Hum Reprod 2021 Jun;50(6):101822. Epub 2020 May 31 doi: 10.1016/j.jogoh.2020.101822. PMID: 32492525
Urinary retention and uterine leiomyomas: a case series and systematic review of the literature.
Wu CQ, Lefebvre G, Frecker H, Husslein H
Int Urogynecol J 2015 Sep;26(9):1277-84. Epub 2015 Mar 10 doi: 10.1007/s00192-015-2665-1. PMID: 25752469

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