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Uterine Non-Neoplastic Disorder

MedGen UID:: 237043
•Concept ID:: C1336920
•: Disease or Syndrome

Synonym:

Uterine Non-Neoplastic Disease

Definition

A non-neoplastic disorder that affects the uterine corpus or the cervix. Representative examples include endometritis, uterine adenomyosis, and cervicitis. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVUterine Non-Neoplastic Disorder

Professional guidelines

PubMed

Study of accuracy of colposcopy in VIA and HPV detection-based cervical cancer screening program.

Ghosh I, Mittal S, Banerjee D, Singh P, Dasgupta S, Chatterjee S, Biswas J, Panda C, Basu P
Aust N Z J Obstet Gynaecol 2014 Dec;54(6):570-5. doi: 10.1111/ajo.12282. PMID: 25476810

Prevalence and genotype distribution of human papillomavirus in non-neoplastic cervical tissue lesion: cervical erosion.

Bayram A, Erkılıç S, Balat Ö, Ekşi F, Uğur MG, Öztürk E, Kaya G
J Med Virol 2011 Nov;83(11):1997-2003. doi: 10.1002/jmv.22218. PMID: 21915876

Expression profiles of ProEx C and Ki67 in squamous cell carcinoma in situ of the skin and their relationship with human papillomavirus genotypes.

Sánchez-Hernández M, Conesa-Zamora P, García-Solano J, Corbalán-Vélez R, Martínez-Barba E, Pérez-Guillermo M
J Cutan Pathol 2010 Jul;37(7):730-6. Epub 2010 Feb 24 doi: 10.1111/j.1600-0560.2010.01530.x. PMID: 20184667

See all (3)

Recent clinical studies

Etiology

PTEN promoter methylation and expression in endometrial cancer tissues.

Khatami F, Shahriari S, Aminimoghaddam S, Klashami ZN, Farahani MS, Teimoori-Toolabi L, Amoli MM, Asadi M, Rashidi BH
Epigenomics 2023 Apr;15(8):507-516. Epub 2023 Jun 21 doi: 10.2217/epi-2023-0099. PMID: 37345350

Gestational trophoblastic disease- rare, sometimes dramatic, and what we know so far.

Strickland AL, Gwin K
Semin Diagn Pathol 2022 May;39(3):228-237. Epub 2022 Mar 22 doi: 10.1053/j.semdp.2022.03.002. PMID: 35400536

Pathology of gestational trophoblastic disease (GTD).

Kaur B
Best Pract Res Clin Obstet Gynaecol 2021 Jul;74:3-28. Epub 2021 Mar 31 doi: 10.1016/j.bpobgyn.2021.02.005. PMID: 34219021

Mesenchymal tumors of the uterine corpus with heterologous and hematopoietic components: a study of ten cases and review of the literature.

Kondi-Pafiti A, Grapsa D, Kairi-Vassilatou E, Kontogianni-Katsarou K, Koliopoulos C, Botsis D
Eur J Gynaecol Oncol 2006;27(1):73-7. PMID: 16550975

"Mesenchymal tumor" or "decidual-like reaction"?

Karbe E
Toxicol Pathol 1999 May-Jun;27(3):354-62. doi: 10.1177/019262339902700312. PMID: 10356713

See all (26)

Diagnosis

PTEN promoter methylation and expression in endometrial cancer tissues.

Gestational trophoblastic disease- rare, sometimes dramatic, and what we know so far.

Strickland AL, Gwin K
Semin Diagn Pathol 2022 May;39(3):228-237. Epub 2022 Mar 22 doi: 10.1053/j.semdp.2022.03.002. PMID: 35400536

Navigating through perplex morphologic changes after exogenous hormone usage.

Chang RJ, Rivera-Colon G, Chen H, Niu S, Carrick K, Lucas E, Gwin K, Zheng W
Semin Diagn Pathol 2022 May;39(3):148-158. Epub 2021 Oct 28 doi: 10.1053/j.semdp.2021.10.001. PMID: 34782217

Pathology of gestational trophoblastic disease (GTD).

Kaur B
Best Pract Res Clin Obstet Gynaecol 2021 Jul;74:3-28. Epub 2021 Mar 31 doi: 10.1016/j.bpobgyn.2021.02.005. PMID: 34219021

Cytopathologic evaluation of patients submitted to radiotherapy for uterine cervix cancer.

Padilha CML, Araújo MLC Junior, Souza SAL
Rev Assoc Med Bras (1992) 2017 Apr;63(4):379-385. doi: 10.1590/1806-9282.63.04.379. PMID: 28614543

See all (36)

Therapy

RKIP inhibition in cervical cancer is associated with higher tumor aggressive behavior and resistance to cisplatin therapy.

Martinho O, Pinto F, Granja S, Miranda-Gonçalves V, Moreira MA, Ribeiro LF, di Loreto C, Rosner MR, Longatto-Filho A, Reis RM
PLoS One 2013;8(3):e59104. Epub 2013 Mar 19 doi: 10.1371/journal.pone.0059104. PMID: 23527098 Free PMC Article

Dynamic spectral imaging colposcopy: higher sensitivity for detection of premalignant cervical lesions.

Louwers J, Zaal A, Kocken M, Ter Harmsel W, Graziosi G, Spruijt J, Berkhof J, Balas C, Papagiannakis E, Snijders P, Meijer C, van Kemenade F, Verheijen R
BJOG 2011 Feb;118(3):309-18. Epub 2010 Dec 23 doi: 10.1111/j.1471-0528.2010.02806.x. PMID: 21176085

Uterine fibroids risk and history of selected medical conditions linked with female hormones.

Parazzini F, Chiaffarino F, Polverino G, Chiantera V, Surace M, La Vecchia C
Eur J Epidemiol 2004;19(3):249-53. doi: 10.1023/b:ejep.0000020448.43323.2a. PMID: 15117118

Steroid receptors in normal, hyperplastic and malignant human endometria.

Vihko R, Jänne O, Kauppila A
Ann Clin Res 1980 Oct;12(5):208-15. PMID: 7015983

Progression of tumours and non-neoplastic disorders as manifestations of a common biological phenomenon.

Burch PR
Med Hypotheses 1978 Mar-Apr;4(2):101-10. doi: 10.1016/0306-9877(78)90054-3. PMID: 642845

See all (5)

Prognosis

Gestational trophoblastic disease- rare, sometimes dramatic, and what we know so far.

Strickland AL, Gwin K
Semin Diagn Pathol 2022 May;39(3):228-237. Epub 2022 Mar 22 doi: 10.1053/j.semdp.2022.03.002. PMID: 35400536

Pathology of gestational trophoblastic disease (GTD).

Kaur B
Best Pract Res Clin Obstet Gynaecol 2021 Jul;74:3-28. Epub 2021 Mar 31 doi: 10.1016/j.bpobgyn.2021.02.005. PMID: 34219021

Clinical impact of de-regulated Notch-1 and Notch-3 in the development and progression of HPV-associated different histological subtypes of precancerous and cancerous lesions of human uterine cervix.

Tripathi R, Rath G, Jawanjal P, Sharma S, Singhal P, Bhambhani S, Hussain S, Bharadwaj M
PLoS One 2014;9(6):e98642. Epub 2014 Jun 6 doi: 10.1371/journal.pone.0098642. PMID: 24905589 Free PMC Article

Mesenchymal tumors of the uterine corpus with heterologous and hematopoietic components: a study of ten cases and review of the literature.

Kondi-Pafiti A, Grapsa D, Kairi-Vassilatou E, Kontogianni-Katsarou K, Koliopoulos C, Botsis D
Eur J Gynaecol Oncol 2006;27(1):73-7. PMID: 16550975

Pathology of gestational trophoblastic diseases.

Cheung AN
Best Pract Res Clin Obstet Gynaecol 2003 Dec;17(6):849-68. doi: 10.1016/s1521-6934(03)00094-4. PMID: 14614885

See all (15)

Clinical prediction guides

PTEN promoter methylation and expression in endometrial cancer tissues.

Transcriptomic Network Analysis Using Exfoliative Cervical Cells Could Discriminate a Potential Risk of Progression to Cancer in HPV-related Cervical Lesions: A Pilot Study.

Park NJ, Choi Y, Lee D, Park JY, Kim JM, Lee YH, Hong DG, Chong GO, Han HS
Cancer Genomics Proteomics 2023 Jan-Feb;20(1):75-87. doi: 10.21873/cgp.20366. PMID: 36581343 Free PMC Article

Intravascular Lymphocytic Accumulation in the Uterine Cervix: A Frequent Finding.

Karpathiou G, Dal P, Chauleur C, Peoc'h M
Int J Gynecol Pathol 2018 May;37(3):229-232. doi: 10.1097/PGP.0000000000000407. PMID: 28582343

Pathology of gestational trophoblastic diseases.

Cheung AN
Best Pract Res Clin Obstet Gynaecol 2003 Dec;17(6):849-68. doi: 10.1016/s1521-6934(03)00094-4. PMID: 14614885

"Mesenchymal tumor" or "decidual-like reaction"?

Karbe E
Toxicol Pathol 1999 May-Jun;27(3):354-62. doi: 10.1177/019262339902700312. PMID: 10356713

See all (22)