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Optic tract astrocytoma

MedGen UID:
237052
•Concept ID:
C1336971
•
Neoplastic Process
Synonyms: astrocytoma (excluding glioblastoma) of optic tract; optic tract astrocytoma; optic tract astrocytoma (excluding glioblastoma); Visual Pathway Astrocytoma; visual pathway astrocytoma
 
Monarch Initiative: MONDO:0024649

Definition

An astrocytoma that affects the visual pathway. This condition can be seen in association with neurofibromatosis 1. It is most commonly seen in the pediatric age group. [from NCI]

Professional guidelines

PubMed

Our treatment philosophy of gliomas of the anterior visual pathways.
Benes V, Julisová I, Julis I
Childs Nerv Syst 1990 Mar;6(2):75-8. doi: 10.1007/BF00307925. PMID: 2340532

Recent clinical studies

Etiology

Edema of the optic tract in patients with tumors of the sellar region: clinical and visual implications in the pediatric population.
Bussat A, Proisy M, Bruneau B, Bouzillé G, Chappé C, Riffaud L
J Neurosurg Pediatr 2018 May;21(5):516-522. Epub 2018 Mar 2 doi: 10.3171/2017.11.PEDS17526. PMID: 29498601
Relationships between brain tumor and optic tract or calcarine fissure are involved in visual field deficits after surgery for brain tumor.
Shinoura N, Suzuki Y, Yamada R, Tabei Y, Saito K, Yagi K
Acta Neurochir (Wien) 2010 Apr;152(4):637-42. Epub 2010 Jan 10 doi: 10.1007/s00701-009-0582-0. PMID: 20063172
Optic tract edema: a highly specific magnetic resonance imaging finding for the diagnosis of craniopharyngiomas.
Hirunpat S, Tanomkiat W, Sriprung H, Chetpaophan J
Acta Radiol 2005 Jul;46(4):419-23. doi: 10.1080/02841850510021599. PMID: 16134321
Recent advances in optic nerve glioma with a focus on the young patient.
Walker D
Curr Opin Neurol 2003 Dec;16(6):657-64. doi: 10.1097/01.wco.0000102628.38669.14. PMID: 14624073
Optic chiasm astrocytomas of childhood. 1. Long-term follow-up.
Medlock MD, Madsen JR, Barnes PD, Anthony DS, Cohen LE, Scott RM
Pediatr Neurosurg 1997 Sep;27(3):121-8. doi: 10.1159/000121239. PMID: 9548522

Diagnosis

Edema of the optic tract in patients with tumors of the sellar region: clinical and visual implications in the pediatric population.
Bussat A, Proisy M, Bruneau B, Bouzillé G, Chappé C, Riffaud L
J Neurosurg Pediatr 2018 May;21(5):516-522. Epub 2018 Mar 2 doi: 10.3171/2017.11.PEDS17526. PMID: 29498601
Pediatric Optic Pathway/Hypothalamic Glioma.
Aihara Y, Chiba K, Eguchi S, Amano K, Kawamata T
Neurol Med Chir (Tokyo) 2018 Jan 15;58(1):1-9. Epub 2017 Nov 9 doi: 10.2176/nmc.ra.2017-0081. PMID: 29118304Free PMC Article
Optic pathway glioma of childhood.
Rasool N, Odel JG, Kazim M
Curr Opin Ophthalmol 2017 May;28(3):289-295. doi: 10.1097/ICU.0000000000000370. PMID: 28257299
Optic tract edema: a highly specific magnetic resonance imaging finding for the diagnosis of craniopharyngiomas.
Hirunpat S, Tanomkiat W, Sriprung H, Chetpaophan J
Acta Radiol 2005 Jul;46(4):419-23. doi: 10.1080/02841850510021599. PMID: 16134321
Optic chiasm astrocytomas of childhood. 1. Long-term follow-up.
Medlock MD, Madsen JR, Barnes PD, Anthony DS, Cohen LE, Scott RM
Pediatr Neurosurg 1997 Sep;27(3):121-8. doi: 10.1159/000121239. PMID: 9548522

Therapy

Integrating functional MRI information into conventional 3D radiotherapy planning of CNS tumors. Is it worth it?
Kovács A, Tóth L, Glavák C, Liposits G, Hadjiev J, Antal G, Emri M, Vandulek C, Repa I
J Neurooncol 2011 Dec;105(3):629-37. Epub 2011 Jul 2 doi: 10.1007/s11060-011-0633-2. PMID: 21725803
Implementation of fiber tract navigation.
Nimsky C, Ganslandt O, Fahlbusch R
Neurosurgery 2006 Apr;58(4 Suppl 2):ONS-292-303; discussion ONS-303-4. doi: 10.1227/01.NEU.0000204726.00088.6D. PMID: 16582653
Management of child optic pathway gliomas: new therapeutical option.
Suárez JC, Viano JC, Zunino S, Herrera EJ, Gomez J, Tramunt B, Marengo I, Hiramatzu E, Miras M, Pena M, Sonzini Astudillo B
Childs Nerv Syst 2006 Jul;22(7):679-84. Epub 2006 Jan 3 doi: 10.1007/s00381-005-0021-3. PMID: 16389565
Three-dimensional conformal radiotherapy for astrocytic tumors involving the eloquent area in children and young adults.
Nishihori T, Shirato H, Aoyama H, Onimaru R, Komae T, Ishii N, Ikeda J, Miyasaka K, Sawamura Y, Iwasaki Y
J Neurooncol 2002 Nov;60(2):177-83. doi: 10.1023/a:1020617717664. PMID: 12635666
Stereotactic radiosurgery for pilocytic astrocytomas when multimodal therapy is necessary.
Hadjipanayis CG, Kondziolka D, Gardner P, Niranjan A, Dagam S, Flickinger JC, Lunsford LD
J Neurosurg 2002 Jul;97(1):56-64. doi: 10.3171/jns.2002.97.1.0056. PMID: 12134933

Prognosis

Edema of the optic tract in patients with tumors of the sellar region: clinical and visual implications in the pediatric population.
Bussat A, Proisy M, Bruneau B, Bouzillé G, Chappé C, Riffaud L
J Neurosurg Pediatr 2018 May;21(5):516-522. Epub 2018 Mar 2 doi: 10.3171/2017.11.PEDS17526. PMID: 29498601
Pediatric Optic Pathway/Hypothalamic Glioma.
Aihara Y, Chiba K, Eguchi S, Amano K, Kawamata T
Neurol Med Chir (Tokyo) 2018 Jan 15;58(1):1-9. Epub 2017 Nov 9 doi: 10.2176/nmc.ra.2017-0081. PMID: 29118304Free PMC Article
Optic pathway glioma of childhood.
Rasool N, Odel JG, Kazim M
Curr Opin Ophthalmol 2017 May;28(3):289-295. doi: 10.1097/ICU.0000000000000370. PMID: 28257299
Recent advances in optic nerve glioma with a focus on the young patient.
Walker D
Curr Opin Neurol 2003 Dec;16(6):657-64. doi: 10.1097/01.wco.0000102628.38669.14. PMID: 14624073
Optic chiasm astrocytomas of childhood. 1. Long-term follow-up.
Medlock MD, Madsen JR, Barnes PD, Anthony DS, Cohen LE, Scott RM
Pediatr Neurosurg 1997 Sep;27(3):121-8. doi: 10.1159/000121239. PMID: 9548522

Clinical prediction guides

Rare Case of Sporadic Malignant Optic Pathway Glioma in 71-Year-Old Woman.
Heiland T, Karpel-Massler G, Scheuerle A, Wirtz CR, Halatsch ME
World Neurosurg 2020 Jan;133:413-415. Epub 2019 Jul 20 doi: 10.1016/j.wneu.2019.07.108. PMID: 31336173
Edema of the optic tract in patients with tumors of the sellar region: clinical and visual implications in the pediatric population.
Bussat A, Proisy M, Bruneau B, Bouzillé G, Chappé C, Riffaud L
J Neurosurg Pediatr 2018 May;21(5):516-522. Epub 2018 Mar 2 doi: 10.3171/2017.11.PEDS17526. PMID: 29498601
Extraretinal induced visual sensations during IMRT of the brain.
Wilhelm-Buchstab T, Buchstab BM, Leitzen C, Garbe S, Müdder T, Oberste-Beulmann S, Sprinkart AM, Simon B, Nelles M, Block W, Schoroth F, Schild HH, Schüller H
PLoS One 2015;10(4):e0123440. Epub 2015 Apr 15 doi: 10.1371/journal.pone.0123440. PMID: 25875609Free PMC Article
Pupillographic investigation of the relative afferent pupillary defect associated with a midbrain lesion.
Kawasaki A, Miller NR, Kardon R
Ophthalmology 2010 Jan;117(1):175-9. doi: 10.1016/j.ophtha.2009.06.053. PMID: 19923003
Recent advances in optic nerve glioma with a focus on the young patient.
Walker D
Curr Opin Neurol 2003 Dec;16(6):657-64. doi: 10.1097/01.wco.0000102628.38669.14. PMID: 14624073

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