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Colorectal Hyperplastic Polyp

MedGen UID:
249037
•Concept ID:
C1112501
•
Neoplastic Process
Synonyms: Colorectal HP; Colorectal Metaplastic Polyp; Colorectal MP; Hyperplastic Large Bowel Polyp; Hyperplastic Polyp of Large Bowel; Hyperplastic Polyp of the Large Bowel

Definition

A serrated polypoid lesion that arises in the colon and rectum. It is usually found in the distant colon and it rarely produces symptoms. This group includes goblet cell rich, mucin poor, and microvesicular hyperplastic polyps. [from NCI]

Professional guidelines

PubMed

Sessile serrated lesions: Clinicopathological characteristics, endoscopic diagnosis, and management.
Murakami T, Kurosawa T, Fukushima H, Shibuya T, Yao T, Nagahara A
Dig Endosc 2022 Sep;34(6):1096-1109. Epub 2022 Mar 29 doi: 10.1111/den.14273. PMID: 35352394
Terminology, Molecular Features, Epidemiology, and Management of Serrated Colorectal Neoplasia.
Crockett SD, Nagtegaal ID
Gastroenterology 2019 Oct;157(4):949-966.e4. Epub 2019 Jul 16 doi: 10.1053/j.gastro.2019.06.041. PMID: 31323292
Magnifying chromoendoscopy: effective diagnostic tool for screening colonoscopy.
Kiesslich R, Neurath MF
J Gastroenterol Hepatol 2007 Nov;22(11):1700-1. doi: 10.1111/j.1440-1746.2007.05203.x. PMID: 17914935

Recent clinical studies

Etiology

Risk of colorectal neoplasm in patients with acromegaly and its relationship with serum growth hormone levels.
Matano Y, Okada T, Suzuki A, Yoneda T, Takeda Y, Mabuchi H
Am J Gastroenterol 2005 May;100(5):1154-60. doi: 10.1111/j.1572-0241.2005.40808.x. PMID: 15842593

Diagnosis

Molecular characteristics of colorectal hyperplastic polyp subgroups.
Ünlü M, Uzun E, Bengi G, Sağol Ö, Sarıoğlu S
Turk J Gastroenterol 2020 Aug;31(8):573-580. doi: 10.5152/tjg.2020.19322. PMID: 32915145Free PMC Article
Minimal influence of expertise on the evaluation of colorectal neoplastic lesions by confocal laser endomicroscopy.
Yuan XM, Li Z, Ji R, Li CQ, Zuo XL, Yu T, Gu XM, Liu J, Wang P, Li M, Li YQ
J Gastroenterol Hepatol 2014 Jan;29(1):91-5. doi: 10.1111/jgh.12357. PMID: 24033829
Risk of colorectal neoplasm in patients with acromegaly and its relationship with serum growth hormone levels.
Matano Y, Okada T, Suzuki A, Yoneda T, Takeda Y, Mabuchi H
Am J Gastroenterol 2005 May;100(5):1154-60. doi: 10.1111/j.1572-0241.2005.40808.x. PMID: 15842593

Prognosis

Minimal influence of expertise on the evaluation of colorectal neoplastic lesions by confocal laser endomicroscopy.
Yuan XM, Li Z, Ji R, Li CQ, Zuo XL, Yu T, Gu XM, Liu J, Wang P, Li M, Li YQ
J Gastroenterol Hepatol 2014 Jan;29(1):91-5. doi: 10.1111/jgh.12357. PMID: 24033829

Clinical prediction guides

Minimal influence of expertise on the evaluation of colorectal neoplastic lesions by confocal laser endomicroscopy.
Yuan XM, Li Z, Ji R, Li CQ, Zuo XL, Yu T, Gu XM, Liu J, Wang P, Li M, Li YQ
J Gastroenterol Hepatol 2014 Jan;29(1):91-5. doi: 10.1111/jgh.12357. PMID: 24033829
A morphological study on the histogenesis of human colorectal hyperplastic polyps.
Araki K, Ogata T, Kobayashi M, Yatani R
Gastroenterology 1995 Nov;109(5):1468-74. doi: 10.1016/0016-5085(95)90632-0. PMID: 7557127

Supplemental Content

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    Practice guidelines

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