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Central nervous system chondroma

MedGen UID:
272474
•Concept ID:
C1333019
•
Neoplastic Process
Synonyms: Central Nervous System Chondroma; central nervous system chondroma; Central Nervous System Osteochondroma; central nervous system osteochondroma; Chondroma of Central Nervous System; chondroma of central nervous system; Chondroma of CNS; chondroma of CNS; Chondroma of the Central Nervous System; chondroma of the central nervous system; Chondroma of the CNS; chondroma of the CNS; CNS Chondroma; CNS chondroma; CNS Osteochondroma; CNS osteochondroma; Osteochondroma of Central Nervous System; osteochondroma of central nervous system; Osteochondroma of CNS; osteochondroma of CNS; Osteochondroma of the Central Nervous System; osteochondroma of the central nervous system; Osteochondroma of the CNS; osteochondroma of the CNS
 
Monarch Initiative: MONDO:0002779

Definition

An extraskeletal chondroma usually arising from the dura. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCentral nervous system chondroma

Professional guidelines

PubMed

Magnetic resonance imaging of rare intracranial neoplasms--role of the in vivo 1 h spectroscopy in the radiological differential diagnostics.
Fortuniak J, Jaskólski DJ, Stefańczyk L, Zawirski M, Gajewicz W
Cent Eur Neurosurg 2010 Nov;71(4):181-8. Epub 2010 Nov 16 doi: 10.1055/s-0030-1261947. PMID: 21082514
Differential diagnosis of an abnormal brain scan.
Alker GJ Jr, Leslie EV, Bakay L
Acta Radiol Diagn (Stockh) 1972;13(0):627-33. doi: 10.1177/02841851720130p218. PMID: 4366252

Recent clinical studies

Etiology

Benign Brain and Spinal Tumors Originating from Bone or Cartilage.
Gami A, Schilling A, Ehresman J, Sciubba DM
Adv Exp Med Biol 2023;1405:457-476. doi: 10.1007/978-3-031-23705-8_17. PMID: 37452949
Early Basal Cortisol Level as a Predictor of Hypothalamic-Pituitary-Adrenal (HPA) Axis Function After Pituitary Tumor Surgery.
Polovina TS, Kraljevic I, Solak M, Balasko A, Haxhiu A, Haxhiu A, Dusek T, Poljicanin T, Kastelan D
Exp Clin Endocrinol Diabetes 2020 Nov;128(11):709-714. Epub 2019 May 15 doi: 10.1055/a-0885-1568. PMID: 31091548
Distinguishing Falcine Chondrosarcomas from Their Mimics and Management.
Omezine S, Bouali S, Taallah M, Zehani A, Kallel J, Jemel H
World Neurosurg 2018 Oct;118:279-283. Epub 2018 Jul 3 doi: 10.1016/j.wneu.2018.06.164. PMID: 30257291
Characteristic CT and MRI findings of intracranial chondroma.
Duan F, Qiu S, Jiang J, Chang J, Liu Z, Lv X, Feng X, Xiong W, An J, Chen J, Yang W, Wen C
Acta Radiol 2012 Dec 1;53(10):1146-54. Epub 2012 Sep 14 doi: 10.1258/ar.2012.120433. PMID: 22983260
A case of dyschondroplasia associated with brain stem glioma: diagnosis by stereotactic biopsy.
Patt S, Weigel K, Mayer HM
Neurosurgery 1990 Sep;27(3):487-91. doi: 10.1097/00006123-199009000-00029. PMID: 2234348

Diagnosis

Intracranial Dural-based Convexity Chondroma.
Kulkarni AV, Sadashiv N, Devi BI, Rao S
Neurol India 2020 Nov-Dec;68(6):1443-1444. doi: 10.4103/0028-3886.304106. PMID: 33342886
Chondroma of the falx cerebri: A case report and review of literature.
Elhakeem AAS, Essa AA, Soliman RK
Neuropathology 2019 Dec;39(6):461-466. Epub 2019 Oct 4 doi: 10.1111/neup.12598. PMID: 31584218
Chondroma of the Falx Cerebri with Central Cystic Degeneration and Hemorrhage: A Case Report.
Al Mohtaseb AH, Hallak AH, Aldaoud N, Rousan LA, Haddad HK, Abuzayed B
Am J Case Rep 2019 Sep 8;20:1331-1335. doi: 10.12659/AJCR.916794. PMID: 31494664Free PMC Article
Distinguishing Falcine Chondrosarcomas from Their Mimics and Management.
Omezine S, Bouali S, Taallah M, Zehani A, Kallel J, Jemel H
World Neurosurg 2018 Oct;118:279-283. Epub 2018 Jul 3 doi: 10.1016/j.wneu.2018.06.164. PMID: 30257291
Tumours of the fifth cranial nerve.
de Benedittis G, Bernasconi V, Ettorre G
Acta Neurochir (Wien) 1977;38(1-2):37-64. doi: 10.1007/BF01401542. PMID: 331889

Therapy

Sellar collision tumor involving pituitary gonadotroph adenoma and chondroma: a potential clinical diagnosis.
Sahli R, Christ E, Kuhlen D, Giger O, Vajtai I
Pituitary 2011 Dec;14(4):405-8. Epub 2009 Sep 17 doi: 10.1007/s11102-009-0199-6. PMID: 19760170
A dose response analysis of injury to cranial nerves and/or nuclei following proton beam radiation therapy.
Urie MM, Fullerton B, Tatsuzaki H, Birnbaum S, Suit HD, Convery K, Skates S, Goitein M
Int J Radiat Oncol Biol Phys 1992;23(1):27-39. doi: 10.1016/0360-3016(92)90540-x. PMID: 1572828

Prognosis

Intracranial Dural-based Convexity Chondroma.
Kulkarni AV, Sadashiv N, Devi BI, Rao S
Neurol India 2020 Nov-Dec;68(6):1443-1444. doi: 10.4103/0028-3886.304106. PMID: 33342886
Chondroma of the Falx Cerebri with Central Cystic Degeneration and Hemorrhage: A Case Report.
Al Mohtaseb AH, Hallak AH, Aldaoud N, Rousan LA, Haddad HK, Abuzayed B
Am J Case Rep 2019 Sep 8;20:1331-1335. doi: 10.12659/AJCR.916794. PMID: 31494664Free PMC Article
Distinguishing Falcine Chondrosarcomas from Their Mimics and Management.
Omezine S, Bouali S, Taallah M, Zehani A, Kallel J, Jemel H
World Neurosurg 2018 Oct;118:279-283. Epub 2018 Jul 3 doi: 10.1016/j.wneu.2018.06.164. PMID: 30257291
Intracranial dural based chondroma.
Reinshagen C, Redjal N, Sajed DP, Nahed BV, Walcott BP
J Clin Neurosci 2016 Mar;25:161-3. Epub 2015 Oct 24 doi: 10.1016/j.jocn.2015.05.052. PMID: 26602798
Distinguishing chordoid meningiomas from their histologic mimics: an immunohistochemical evaluation.
Sangoi AR, Dulai MS, Beck AH, Brat DJ, Vogel H
Am J Surg Pathol 2009 May;33(5):669-81. doi: 10.1097/PAS.0b013e318194c566. PMID: 19194275Free PMC Article

Clinical prediction guides

Early Basal Cortisol Level as a Predictor of Hypothalamic-Pituitary-Adrenal (HPA) Axis Function After Pituitary Tumor Surgery.
Polovina TS, Kraljevic I, Solak M, Balasko A, Haxhiu A, Haxhiu A, Dusek T, Poljicanin T, Kastelan D
Exp Clin Endocrinol Diabetes 2020 Nov;128(11):709-714. Epub 2019 May 15 doi: 10.1055/a-0885-1568. PMID: 31091548
Connection between expression of inducible nitric oxide synthase (iNOS) in skull base chordoma and lower urinary tract symptoms.
Akhavan-Sigari R, Ostertag H, Rohde V, Tezval H
Int Urol Nephrol 2014 Nov;46(11):2109-16. Epub 2014 Aug 12 doi: 10.1007/s11255-014-0806-y. PMID: 25113512
Characteristic CT and MRI findings of intracranial chondroma.
Duan F, Qiu S, Jiang J, Chang J, Liu Z, Lv X, Feng X, Xiong W, An J, Chen J, Yang W, Wen C
Acta Radiol 2012 Dec 1;53(10):1146-54. Epub 2012 Sep 14 doi: 10.1258/ar.2012.120433. PMID: 22983260
Distinguishing chordoid meningiomas from their histologic mimics: an immunohistochemical evaluation.
Sangoi AR, Dulai MS, Beck AH, Brat DJ, Vogel H
Am J Surg Pathol 2009 May;33(5):669-81. doi: 10.1097/PAS.0b013e318194c566. PMID: 19194275Free PMC Article
D2-40 functions as an effective chondroid marker distinguishing true chondroid tumors from chordoma.
Huse JT, Pasha TL, Zhang PJ
Acta Neuropathol 2007 Jan;113(1):87-94. Epub 2006 Sep 26 doi: 10.1007/s00401-006-0140-2. PMID: 17021752

Recent systematic reviews

Intracranial Dural Parafalcine Chondroma: Case Report and Systematic Review of the Literature.
Sullivan JC, Goldsmith J, Rojas R, Varma H, Kasper EM
World Neurosurg 2019 Feb;122:1-7. Epub 2018 Sep 29 doi: 10.1016/j.wneu.2018.09.169. PMID: 30273721

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