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Skin Lipomatous Neoplasm

MedGen UID:
272513
•Concept ID:
C1333174
•
Neoplastic Process
Synonyms: Cutaneous Lipomatous Neoplasm; Cutaneous Lipomatous Tumor; Lipomatous Neoplasm of Skin; Lipomatous Neoplasm of the Skin; Lipomatous Skin Neoplasm; Lipomatous Skin Tumor; Lipomatous Tumor of Skin; Lipomatous Tumor of the Skin

Definition

An adipose tissue neoplasm arising from the skin. [from NCI]

Professional guidelines

PubMed

Radiologic and Clinical Features of Infantile Hemangioma: Potential Pitfalls and Differential Diagnosis.
Inarejos Clemente EJ, Diaz Leyva J, Karakas SP, Duarte AM, Mas TR, Restrepo R
Radiographics 2023 Nov;43(11):e230064. doi: 10.1148/rg.230064. PMID: 37883305
Toward clinical and molecular dissection of frontonasal dysplasia with facial skin polyps: From Pai syndrome to differential diagnosis through a series of 27 patients.
Lehalle D, Bruel AL, Vitobello A, Denommé-Pichon AS, Duffourd Y, Assoum M, Amiel J, Baujat G, Bessieres B, Bigoni S, Burglen L, Captier G, Dard R, Edery P, Fortunato F, Geneviève D, Goldenberg A, Guibaud L, Héron D, Holder-Espinasse M, Lederer D, Lopez Grondona F, Grotto S, Marlin S, Nadeau G, Picard A, Rossi M, Roume J, Sanlaville D, Saugier-Veber P, Triau S, Valenzuela Palafoll MI, Vanlerberghe C, Van Maldergem L, Vezain M, Vincent-Delorme C, Zivi E, Thevenon J, Vabres P, Thauvin-Robinet C, Callier P, Faivre L
Am J Med Genet A 2022 Jul;188(7):2036-2047. Epub 2022 Apr 21 doi: 10.1002/ajmg.a.62739. PMID: 35445792
Postirradiation Capsular Contracture in Implant-Based Breast Reconstruction: Management and Outcome.
Haran O, Bracha G, Tiosano A, Menes T, Madah E, Gur E, Barnea Y, Arad E
Plast Reconstr Surg 2021 Jan 1;147(1):11-19. doi: 10.1097/PRS.0000000000007453. PMID: 33002986

Recent clinical studies

Etiology

Fundamentals of Skin Bioimpedances.
Lo Presti A, Montoya NA, Criscuolo V, Khan G, Khan U, Vecchione R, Falconi C
Adv Mater 2023 Aug;35(33):e2302127. Epub 2023 Jul 8 doi: 10.1002/adma.202302127. PMID: 37252818
Beyond the "3 Ps": A critical appraisal of the non-endocrine manifestations of multiple endocrine neoplasia type 1.
Waguespack SG
Front Endocrinol (Lausanne) 2022;13:1029041. Epub 2022 Oct 17 doi: 10.3389/fendo.2022.1029041. PMID: 36325452Free PMC Article
Orthopedic issues in vascular anomalies.
Spencer SA, Sorger JI
Semin Pediatr Surg 2020 Oct;29(5):150973. Epub 2020 Sep 19 doi: 10.1016/j.sempedsurg.2020.150973. PMID: 33069292
Muscle-Organ Crosstalk: The Emerging Roles of Myokines.
Severinsen MCK, Pedersen BK
Endocr Rev 2020 Aug 1;41(4):594-609. doi: 10.1210/endrev/bnaa016. PMID: 32393961Free PMC Article
Nonepithelial Tumors and Tumor-like Lesions of the Skin and Subcutis in Children.
Dehner LP, Gru AA
Pediatr Dev Pathol 2018 Mar-Apr;21(2):150-207. doi: 10.1177/1093526617751529. PMID: 29607758

Diagnosis

Ultrasound of congenital spine anomalies.
Rees MA, Squires JH, Coley BD, Hoehne B, Ho ML
Pediatr Radiol 2021 Dec;51(13):2442-2457. Epub 2021 Sep 16 doi: 10.1007/s00247-021-05178-6. PMID: 34532816
Pai syndrome: a review.
Olivero F, Foiadelli T, Luzzi S, Marseglia GL, Savasta S
Childs Nerv Syst 2020 Nov;36(11):2635-2640. Epub 2020 Jul 10 doi: 10.1007/s00381-020-04788-z. PMID: 32651596Free PMC Article
Tuberous Sclerosis.
Javaid A, Shabbir Z, Din IU
J Pak Med Assoc 2019 Mar;69(3):445. PMID: 30890846
Nonepithelial Tumors and Tumor-like Lesions of the Skin and Subcutis in Children.
Dehner LP, Gru AA
Pediatr Dev Pathol 2018 Mar-Apr;21(2):150-207. doi: 10.1177/1093526617751529. PMID: 29607758
Tumors of the hand.
Mavrogenis AF, Panagopoulos GN, Angelini A, Lesenský J, Vottis C, Megaloikonomos PD, Kokkalis ZT, Kontogeorgakos V, Ruggieri P, Papagelopoulos PJ
Eur J Orthop Surg Traumatol 2017 Aug;27(6):747-762. Epub 2017 Jun 5 doi: 10.1007/s00590-017-1984-y. PMID: 28585186

Therapy

Rapamycin and rapalogs for tuberous sclerosis complex.
Sasongko TH, Kademane K, Chai Soon Hou S, Jocelyn TXY, Zabidi-Hussin Z
Cochrane Database Syst Rev 2023 Jul 11;7(7):CD011272. doi: 10.1002/14651858.CD011272.pub3. PMID: 37432030Free PMC Article
SKIN AND SUBCUTANEOUS ADIPOSE TISSUE DAMAGE AFTER RADIATION THERAPY IN BREAST CANCER PATIENTS.
Bazyka DA, Litvinenko OO, Bugaytsov SG, Shakhrai GF
Probl Radiac Med Radiobiol 2021 Dec;26:18-35. doi: 10.33145/2304-8336-2021-26-18-35. PMID: 34965541
What's New in Genetic Skin Diseases.
Hill CR, Theos A
Dermatol Clin 2019 Apr;37(2):229-239. doi: 10.1016/j.det.2018.11.004. PMID: 30850045
Tuberous sclerosis complex.
Henske EP, Jóźwiak S, Kingswood JC, Sampson JR, Thiele EA
Nat Rev Dis Primers 2016 May 26;2:16035. doi: 10.1038/nrdp.2016.35. PMID: 27226234
Update on imaging of the postsurgical breast.
Margolis NE, Morley C, Lotfi P, Shaylor SD, Palestrant S, Moy L, Melsaether AN
Radiographics 2014 May-Jun;34(3):642-60. doi: 10.1148/rg.343135059. PMID: 24819786

Prognosis

The Interplay between Tumour Microenvironment Components in Malignant Melanoma.
Amalinei C, Grigoraș A, Lozneanu L, Căruntu ID, Giușcă SE, Balan RA
Medicina (Kaunas) 2022 Mar 2;58(3) doi: 10.3390/medicina58030365. PMID: 35334544Free PMC Article
Orthopedic issues in vascular anomalies.
Spencer SA, Sorger JI
Semin Pediatr Surg 2020 Oct;29(5):150973. Epub 2020 Sep 19 doi: 10.1016/j.sempedsurg.2020.150973. PMID: 33069292
The role of leptin in selected skin diseases.
Dopytalska K, Baranowska-Bik A, Roszkiewicz M, Bik W, Walecka I
Lipids Health Dis 2020 Oct 2;19(1):215. doi: 10.1186/s12944-020-01391-8. PMID: 33008429Free PMC Article
Pancreatic panniculitis.
Rongioletti F, Caputo V
G Ital Dermatol Venereol 2013 Aug;148(4):419-25. PMID: 23900163
Cutaneous lipomatous neoplasms.
Mentzel T
Semin Diagn Pathol 2001 Nov;18(4):250-7. PMID: 11757864

Clinical prediction guides

Rapamycin and rapalogs for tuberous sclerosis complex.
Sasongko TH, Kademane K, Chai Soon Hou S, Jocelyn TXY, Zabidi-Hussin Z
Cochrane Database Syst Rev 2023 Jul 11;7(7):CD011272. doi: 10.1002/14651858.CD011272.pub3. PMID: 37432030Free PMC Article
PRDM10 RCC: A Birt-Hogg-Dubé-like Syndrome Associated With Lipoma and Highly Penetrant, Aggressive Renal Tumors Morphologically Resembling Type 2 Papillary Renal Cell Carcinoma.
Schmidt LS, Vocke CD, Ricketts CJ, Blake Z, Choo KK, Nielsen D, Gautam R, Crooks DR, Reynolds KL, Krolus JL, Bashyal M, Karim B, Cowen EW, Malayeri AA, Merino MJ, Srinivasan R, Ball MW, Zbar B, Marston Linehan W
Urology 2023 Sep;179:58-70. Epub 2023 Jun 16 doi: 10.1016/j.urology.2023.04.035. PMID: 37331486Free PMC Article
Corpus Callosum Lipomas in Children.
Gezer B, Karabagli H, Koktekir E, Sahinoglu M, Karabagli P
Turk Neurosurg 2020;30(4):573-576. doi: 10.5137/1019-5149.JTN.27692-19.6. PMID: 32530476
Tissue-resident lymphocytes: from adaptive to innate immunity.
Sun H, Sun C, Xiao W, Sun R
Cell Mol Immunol 2019 Mar;16(3):205-215. Epub 2019 Jan 11 doi: 10.1038/s41423-018-0192-y. PMID: 30635650Free PMC Article
PEComa: what do we know so far?
Hornick JL, Fletcher CD
Histopathology 2006 Jan;48(1):75-82. doi: 10.1111/j.1365-2559.2005.02316.x. PMID: 16359539

Recent systematic reviews

Rapamycin and rapalogs for tuberous sclerosis complex.
Sasongko TH, Kademane K, Chai Soon Hou S, Jocelyn TXY, Zabidi-Hussin Z
Cochrane Database Syst Rev 2023 Jul 11;7(7):CD011272. doi: 10.1002/14651858.CD011272.pub3. PMID: 37432030Free PMC Article
Efficacy of breast reconstruction with fat grafting: A systematic review and meta-analysis.
Herly M, Ørholt M, Larsen A, Pipper CB, Bredgaard R, Gramkow CS, Katz AJ, Drzewiecki KT, Vester-Glowinski PV
J Plast Reconstr Aesthet Surg 2018 Dec;71(12):1740-1750. Epub 2018 Sep 4 doi: 10.1016/j.bjps.2018.08.024. PMID: 30245019
Rapamycin and rapalogs for tuberous sclerosis complex.
Sasongko TH, Ismail NF, Zabidi-Hussin Z
Cochrane Database Syst Rev 2016 Jul 13;7(7):CD011272. doi: 10.1002/14651858.CD011272.pub2. PMID: 27409709Free PMC Article
Iatrogenic surgical microscope skin burns: A systematic review of the literature and case report.
Lopez J, Soni A, Calva D, Susarla SM, Jallo GI, Redett R
Burns 2016 Jun;42(4):e74-80. Epub 2016 Jan 15 doi: 10.1016/j.burns.2015.08.014. PMID: 26777456
Efficacy and safety of sirolimus for renal angiomyolipoma in patients with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis: a systematic review.
Peng ZF, Yang L, Wang TT, Han P, Liu ZH, Wei Q
J Urol 2014 Nov;192(5):1424-30. Epub 2014 May 9 doi: 10.1016/j.juro.2014.04.096. PMID: 24813310

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