Polyvesicular vitelline pattern testicular yolk sac tumor

MedGen UID:: 273638
•Concept ID:: C1515311
•: Neoplastic Process

Synonyms:	polyvesicular vitelline pattern testicular yolk sac tumor; Testicular Yolk Sac Tumor, Polyvesicular Vitelline Pattern; testicular yolk Sac tumor, polyvesicular vitelline pattern

Monarch Initiative:	MONDO:0004219

Definition

A yolk sac tumor that arises from the testis and is characterized by the presence of collections of vesicles that are surrounded by connective tissue. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVPolyvesicular vitelline pattern testicular yolk sac tumor

Neoplasm by Morphology
- Germ cell tumor
  - Germ cell tumor of testis
    - Malignant testicular germ cell tumor
      - Testicular non-seminomatous germ cell cancer
        Testicular yolk sac tumor
        Polyvesicular vitelline pattern testicular yolk sac tumor

Recent clinical studies

Diagnosis

FoxA2 is a reliable marker for the diagnosis of yolk sac tumour postpubertal-type.

Ricci C, Ambrosi F, Franceschini T, Giunchi F, Di Filippo G, Franchini E, Massari F, Mollica V, Tateo V, Bianchi FM, Colecchia M, Acosta AM, Fiorentino M
Histopathology 2023 Sep;83(3):465-476. Epub 2023 Jun 14 doi: 10.1111/his.14968. PMID: 37317674

Glypican 3 has a higher sensitivity than alpha-fetoprotein for testicular and ovarian yolk sac tumour: immunohistochemical investigation with analysis of histological growth patterns.

Zynger DL, McCallum JC, Luan C, Chou PM, Yang XJ
Histopathology 2010 May;56(6):750-7. doi: 10.1111/j.1365-2559.2010.03553.x. PMID: 20546340

Pure yolk sac tumors in genital and extragenital sites: study on three pedriatic cases, with cytological findings on two.

Sironi M, Assi A, Quaglia G, Tonnarelli G, Cozzi L
Adv Clin Path 1999 Jul;3(3):55-62. PMID: 10655574

See all (3)