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Tumor Promotion

MedGen UID:
274320
Concept ID:
C1519689
Neoplastic Process

Definition

The second step in two-stage carcinogenesis: the conversion of an initiated (premalignant) cell to malignancy. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTumor Promotion

Professional guidelines

PubMed

Liao KL, Watt KD
Bull Math Biol 2022 Jul 6;84(8):82. doi: 10.1007/s11538-022-01039-x. PMID: 35792958
Clergé A, Le Goff J, Lopez C, Ledauphin J, Delépée R
Crit Rev Toxicol 2019 Apr;49(4):302-328. Epub 2019 Sep 12 doi: 10.1080/10408444.2019.1605333. PMID: 31512557
Mahony C, Felter SP, McMillan DA
Regul Toxicol Pharmacol 2006 Mar;44(2):75-82. Epub 2005 Nov 10 doi: 10.1016/j.yrtph.2005.09.003. PMID: 16289279

Recent clinical studies

Etiology

Calabrese EJ, Priest ND, Kozumbo WJ
Chem Biol Interact 2021 May 25;341:109464. Epub 2021 Apr 3 doi: 10.1016/j.cbi.2021.109464. PMID: 33823170
Perillo B, Di Donato M, Pezone A, Di Zazzo E, Giovannelli P, Galasso G, Castoria G, Migliaccio A
Exp Mol Med 2020 Feb;52(2):192-203. Epub 2020 Feb 14 doi: 10.1038/s12276-020-0384-2. PMID: 32060354Free PMC Article
Turesky RJ
Chimia (Aarau) 2018 Oct 31;72(10):718-724. doi: 10.2533/chimia.2018.718. PMID: 30376922Free PMC Article
Tilg H, Adolph TE, Gerner RR, Moschen AR
Cancer Cell 2018 Jun 11;33(6):954-964. Epub 2018 Apr 12 doi: 10.1016/j.ccell.2018.03.004. PMID: 29657127
Andres S, Pevny S, Ziegenhagen R, Bakhiya N, Schäfer B, Hirsch-Ernst KI, Lampen A
Mol Nutr Food Res 2018 Jan;62(1) Epub 2017 Dec 19 doi: 10.1002/mnfr.201700447. PMID: 29127724

Diagnosis

Lin SC, Liao YC, Chen PM, Yang YY, Wang YH, Tung SL, Chuang CM, Sung YW, Jang TH, Chuang SE, Wang LH
J Biomed Sci 2022 Dec 22;29(1):109. doi: 10.1186/s12929-022-00888-x. PMID: 36550569Free PMC Article
Mahmoudi A, Moadab F, Safdarian E, Navashenaq JG, Rezaee M, Gheibihayat SM
Mini Rev Med Chem 2022;22(20):2641-2660. doi: 10.2174/1389557522666220330150937. PMID: 35362375
Giraud J, Chalopin D, Blanc JF, Saleh M
Front Immunol 2021;12:655697. Epub 2021 Mar 18 doi: 10.3389/fimmu.2021.655697. PMID: 33815418Free PMC Article
Lappano R, Jacquot Y, Maggiolini M
Int J Mol Sci 2018 Dec 2;19(12) doi: 10.3390/ijms19123840. PMID: 30513833Free PMC Article
Huang T, Song X, Yang Y, Wan X, Alvarez AA, Sastry N, Feng H, Hu B, Cheng SY
Crit Rev Oncog 2018;23(5-6):247-267. doi: 10.1615/CritRevOncog.2018027913. PMID: 30311559Free PMC Article

Therapy

Calabrese EJ, Priest ND, Kozumbo WJ
Chem Biol Interact 2021 May 25;341:109464. Epub 2021 Apr 3 doi: 10.1016/j.cbi.2021.109464. PMID: 33823170
Black AR, Black JD
Adv Biol Regul 2021 May;80:100769. Epub 2020 Nov 23 doi: 10.1016/j.jbior.2020.100769. PMID: 33307285Free PMC Article
Turesky RJ
Chimia (Aarau) 2018 Oct 31;72(10):718-724. doi: 10.2533/chimia.2018.718. PMID: 30376922Free PMC Article
Andres S, Pevny S, Ziegenhagen R, Bakhiya N, Schäfer B, Hirsch-Ernst KI, Lampen A
Mol Nutr Food Res 2018 Jan;62(1) Epub 2017 Dec 19 doi: 10.1002/mnfr.201700447. PMID: 29127724
Menon VP, Sudheer AR
Adv Exp Med Biol 2007;595:105-25. doi: 10.1007/978-0-387-46401-5_3. PMID: 17569207

Prognosis

Lin SC, Liao YC, Chen PM, Yang YY, Wang YH, Tung SL, Chuang CM, Sung YW, Jang TH, Chuang SE, Wang LH
J Biomed Sci 2022 Dec 22;29(1):109. doi: 10.1186/s12929-022-00888-x. PMID: 36550569Free PMC Article
Calabrese EJ, Priest ND, Kozumbo WJ
Chem Biol Interact 2021 May 25;341:109464. Epub 2021 Apr 3 doi: 10.1016/j.cbi.2021.109464. PMID: 33823170
Yang H, Zhang Q, Xu M, Wang L, Chen X, Feng Y, Li Y, Zhang X, Cui W, Jia X
Mol Cancer 2020 Feb 27;19(1):41. doi: 10.1186/s12943-020-01165-x. PMID: 32103760Free PMC Article
Lappano R, Jacquot Y, Maggiolini M
Int J Mol Sci 2018 Dec 2;19(12) doi: 10.3390/ijms19123840. PMID: 30513833Free PMC Article
Cosmetic Ingredient Review Expert Panel
Int J Toxicol 2005;24 Suppl 5:1-31. doi: 10.1080/10915810500434183. PMID: 16596767

Clinical prediction guides

Calabrese EJ, Agathokleous E, Dhawan G, Kapoor R, Dhawan V, Manes PK, Calabrese V
Nitric Oxide 2023 Apr 1;133:1-17. Epub 2023 Feb 8 doi: 10.1016/j.niox.2023.02.001. PMID: 36764605
Lin SC, Liao YC, Chen PM, Yang YY, Wang YH, Tung SL, Chuang CM, Sung YW, Jang TH, Chuang SE, Wang LH
J Biomed Sci 2022 Dec 22;29(1):109. doi: 10.1186/s12929-022-00888-x. PMID: 36550569Free PMC Article
Calabrese EJ, Priest ND, Kozumbo WJ
Chem Biol Interact 2021 May 25;341:109464. Epub 2021 Apr 3 doi: 10.1016/j.cbi.2021.109464. PMID: 33823170
Yang H, Zhang Q, Xu M, Wang L, Chen X, Feng Y, Li Y, Zhang X, Cui W, Jia X
Mol Cancer 2020 Feb 27;19(1):41. doi: 10.1186/s12943-020-01165-x. PMID: 32103760Free PMC Article
Cosmetic Ingredient Review Expert Panel
Int J Toxicol 2005;24 Suppl 5:1-31. doi: 10.1080/10915810500434183. PMID: 16596767

Recent systematic reviews

Kandathil SA, Akhondi A, Kadletz-Wanke L, Heiduschka G, Engedal N, Brkic FF
J Cancer Res Clin Oncol 2024 Jan 31;150(2):56. doi: 10.1007/s00432-023-05514-3. PMID: 38291202Free PMC Article
Hung YC, Pan TL, Hu WL
Oxid Med Cell Longev 2016;2016:5293284. Epub 2016 Aug 4 doi: 10.1155/2016/5293284. PMID: 27579153Free PMC Article
Pikoulis E, Margonis GA, Angelou A, Zografos GC, Antoniou E
Eur J Cancer Prev 2016 Mar;25(2):102-8. doi: 10.1097/CEJ.0000000000000152. PMID: 25768976
Deodati A, Ferroli BB, Cianfarani S
Growth Horm IGF Res 2014 Aug;24(4):105-11. Epub 2014 Apr 13 doi: 10.1016/j.ghir.2014.02.001. PMID: 24818783
Repacholi MH, Lerchl A, Röösli M, Sienkiewicz Z, Auvinen A, Breckenkamp J, d'Inzeo G, Elliott P, Frei P, Heinrich S, Lagroye I, Lahkola A, McCormick DL, Thomas S, Vecchia P
Bioelectromagnetics 2012 Apr;33(3):187-206. Epub 2011 Oct 21 doi: 10.1002/bem.20716. PMID: 22021071

Supplemental Content

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