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Malignant Mixed Epithelial and Mesenchymal Neoplasm of the Cervix

MedGen UID:
274750
Concept ID:
C1518168
Neoplastic Process
Synonym: Malignant Cervical Mixed Epithelial and Mesenchymal Neoplasm

Definition

A mixed epithelial and mesenchymal neoplasm that arises from the cervix. It is characterized by the presence of malignant mesenchymal elements and benign or malignant epithelial elements. This category includes adenosarcoma and carcinosarcoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Mixed Epithelial and Mesenchymal Neoplasm of the Cervix

Recent clinical studies

Etiology

Mühlenbrock MV, Navarrete-Rey P, Kovoor E, Guzman-Rojas R, Troncoso F, Miranda-Mendoza I
J Gynecol Obstet Hum Reprod 2021 Sep;50(7):101992. Epub 2020 Nov 17 doi: 10.1016/j.jogoh.2020.101992. PMID: 33217603
Lopez-Chardi L, González-Bosquet E, Rovira Zurriaga C, Laïlla Vicens JM
Eur J Gynaecol Oncol 2013;34(4):336-8. PMID: 24020142
Haberal A, Cil AP, Gunes M, Cavusoglu D
Ultrasound Obstet Gynecol 2005 Aug;26(2):186-7. doi: 10.1002/uog.1948. PMID: 16041681

Diagnosis

Park E, Kim YT, Kim S, Nam EJ, Cho NH
Mod Pathol 2021 Sep;34(9):1738-1749. Epub 2021 Jun 8 doi: 10.1038/s41379-021-00829-3. PMID: 34103667
Mühlenbrock MV, Navarrete-Rey P, Kovoor E, Guzman-Rojas R, Troncoso F, Miranda-Mendoza I
J Gynecol Obstet Hum Reprod 2021 Sep;50(7):101992. Epub 2020 Nov 17 doi: 10.1016/j.jogoh.2020.101992. PMID: 33217603
Mohammad N, Haimes JD, Mishkin S, Kudlow BA, Leong MY, Chew SH, Koay E, Whitehouse A, Cope N, Ali RH, Köbel M, Stewart CJR, McCluggage WG, Lee CH
Am J Surg Pathol 2018 Oct;42(10):1353-1359. doi: 10.1097/PAS.0000000000001120. PMID: 30015720
Patnayak R, Rukmangadha N, Architha P, Reddy GS, Lakshmi AY, Kannan T, Jena A
Indian J Pathol Microbiol 2018 Jul-Sep;61(3):440-442. doi: 10.4103/IJPM.IJPM_1_18. PMID: 30004077
Lopez-Chardi L, González-Bosquet E, Rovira Zurriaga C, Laïlla Vicens JM
Eur J Gynaecol Oncol 2013;34(4):336-8. PMID: 24020142

Therapy

Patnayak R, Rukmangadha N, Architha P, Reddy GS, Lakshmi AY, Kannan T, Jena A
Indian J Pathol Microbiol 2018 Jul-Sep;61(3):440-442. doi: 10.4103/IJPM.IJPM_1_18. PMID: 30004077

Prognosis

Nakai G, Matsutani H, Yamada T, Ohmichi M, Yamamoto K, Osuga K
BMC Womens Health 2021 Dec 16;21(1):416. doi: 10.1186/s12905-021-01567-z. PMID: 34915866Free PMC Article
Mühlenbrock MV, Navarrete-Rey P, Kovoor E, Guzman-Rojas R, Troncoso F, Miranda-Mendoza I
J Gynecol Obstet Hum Reprod 2021 Sep;50(7):101992. Epub 2020 Nov 17 doi: 10.1016/j.jogoh.2020.101992. PMID: 33217603
Hacking S, Chavarria H, Jin C, Perry A, Nasim M
Pathol Res Pract 2020 Apr;216(4):152847. Epub 2020 Jan 31 doi: 10.1016/j.prp.2020.152847. PMID: 32085927
Mohammad N, Haimes JD, Mishkin S, Kudlow BA, Leong MY, Chew SH, Koay E, Whitehouse A, Cope N, Ali RH, Köbel M, Stewart CJR, McCluggage WG, Lee CH
Am J Surg Pathol 2018 Oct;42(10):1353-1359. doi: 10.1097/PAS.0000000000001120. PMID: 30015720
Tseng CE, Chen CH, Chen SJ, Chi CL
Int J Clin Exp Pathol 2014;7(3):1212-7. Epub 2014 Feb 15 PMID: 24696739Free PMC Article

Clinical prediction guides

Nakai G, Matsutani H, Yamada T, Ohmichi M, Yamamoto K, Osuga K
BMC Womens Health 2021 Dec 16;21(1):416. doi: 10.1186/s12905-021-01567-z. PMID: 34915866Free PMC Article
Mühlenbrock MV, Navarrete-Rey P, Kovoor E, Guzman-Rojas R, Troncoso F, Miranda-Mendoza I
J Gynecol Obstet Hum Reprod 2021 Sep;50(7):101992. Epub 2020 Nov 17 doi: 10.1016/j.jogoh.2020.101992. PMID: 33217603
Hacking S, Chavarria H, Jin C, Perry A, Nasim M
Pathol Res Pract 2020 Apr;216(4):152847. Epub 2020 Jan 31 doi: 10.1016/j.prp.2020.152847. PMID: 32085927
Mohammad N, Haimes JD, Mishkin S, Kudlow BA, Leong MY, Chew SH, Koay E, Whitehouse A, Cope N, Ali RH, Köbel M, Stewart CJR, McCluggage WG, Lee CH
Am J Surg Pathol 2018 Oct;42(10):1353-1359. doi: 10.1097/PAS.0000000000001120. PMID: 30015720
Buza N, Tavassoli FA
Int J Gynecol Pathol 2009 Nov;28(6):514-21. doi: 10.1097/PGP.0b013e3181a934e9. PMID: 19851197

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