U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Ovarian Low Grade Endometrioid Stromal Sarcoma

MedGen UID:
276498
•Concept ID:
C1518022
•
Neoplastic Process
Synonyms: Endometrioid Stromal Sarcoma of the Ovary; Low Grade Endometrioid Stromal Sarcoma of the Ovary; Ovarian Endometrioid Stromal Sarcoma

Definition

A rare invasive mesenchymal tumor that arises from the ovary. It is characterized by the absence of marked pleomorphism and nuclear atypia in the neoplastic mesenchymal cells. It may have a favorable clinical outcome. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOvarian Low Grade Endometrioid Stromal Sarcoma

Professional guidelines

PubMed

Endometrial stromal tumors of the uterus: Epidemiology, pathological and biological features, treatment options and clinical outcomes.
Gadducci A, Multinu F, De Vitis LA, Cosio S, Carinelli S, Aletti GD
Gynecol Oncol 2023 Apr;171:95-105. Epub 2023 Feb 24 doi: 10.1016/j.ygyno.2023.02.009. PMID: 36842409
Annual report of the Committee on Gynecologic Oncology, the Japan Society of Obstetrics and Gynecology: Annual patient report for 2017 and annual treatment report for 2012.
Nagase S, Ohta T, Takahashi F, Yaegashi N; Board members of the 2020 Committee on Gynecologic Oncology of the Japan Society of Obstetrics and Gynecology
J Obstet Gynaecol Res 2021 May;47(5):1631-1642. Epub 2021 Feb 25 doi: 10.1111/jog.14724. PMID: 33631867
Fertility after the treatment of gynecologic tumors.
Kesic V
Recent Results Cancer Res 2008;178:79-95. doi: 10.1007/978-3-540-71274-9_9. PMID: 18080446

Recent clinical studies

Etiology

Ovarian preservation in gynecologic oncology: current indications and techniques.
Bizzarri N, Pavone M, Loverro M, Querleu D, Fagotti A, Scambia G
Curr Opin Oncol 2023 Sep 1;35(5):401-411. Epub 2023 Jul 13 doi: 10.1097/CCO.0000000000000969. PMID: 37498120
Endometrioid Borderline Ovarian Tumor: Clinical Characteristics, Prognosis, and Managements.
Ricotta G, Maulard A, Candiani M, Scherrier S, Genestie C, Pautier P, Leary A, Chargari C, Mangili G, Morice P, Gouy S
Ann Surg Oncol 2022 Sep;29(9):5894-5903. Epub 2022 May 19 doi: 10.1245/s10434-022-11893-7. PMID: 35590116
Gynecological lesions in hereditary cancer predisposition syndromes.
Dundr P, Cibula D, Foretová L, Macek M Jr, Kopečková K, Petruželka L, Němejcová K, Bártů M, Hojný J, Hájková N, Jakša R, Janega P, Stružinská I
Cesk Patol 2021 Summer;57(2):96-104. PMID: 34275319
The prognosis of recurrent low-grade endometrial stromal sarcoma: a retrospective cohort study.
Dai Q, Xu B, Wu H, You Y, Wu M, Li L
Orphanet J Rare Dis 2021 Apr 7;16(1):160. doi: 10.1186/s13023-021-01802-8. PMID: 33827628Free PMC Article
Low grade endometrial stromal sarcoma of uterine: review of 17 cases.
Behtash N, Akhavan S, Gilani MM, Mousavi A, Ghaemmaghami F, Mazhari MM
Acta Med Iran 2011;49(9):619-24. PMID: 22052146

Diagnosis

Ovarian preservation in gynecologic oncology: current indications and techniques.
Bizzarri N, Pavone M, Loverro M, Querleu D, Fagotti A, Scambia G
Curr Opin Oncol 2023 Sep 1;35(5):401-411. Epub 2023 Jul 13 doi: 10.1097/CCO.0000000000000969. PMID: 37498120
Endometrial stromal tumors of the uterus: Epidemiology, pathological and biological features, treatment options and clinical outcomes.
Gadducci A, Multinu F, De Vitis LA, Cosio S, Carinelli S, Aletti GD
Gynecol Oncol 2023 Apr;171:95-105. Epub 2023 Feb 24 doi: 10.1016/j.ygyno.2023.02.009. PMID: 36842409
Identifying SOX17 as a Sensitive and Specific Marker for Ovarian and Endometrial Carcinomas.
Shaker N, Chen W, Sinclair W, Parwani AV, Li Z
Mod Pathol 2023 Jan;36(1):100038. doi: 10.1016/j.modpat.2022.100038. PMID: 36788073
Update on Uterine Mesenchymal Neoplasms.
Kertowidjojo EC, Bennett JA
Surg Pathol Clin 2022 Jun;15(2):315-340. Epub 2022 May 20 doi: 10.1016/j.path.2022.02.008. PMID: 35715164
Low grade endometrial stromal sarcoma of uterine: review of 17 cases.
Behtash N, Akhavan S, Gilani MM, Mousavi A, Ghaemmaghami F, Mazhari MM
Acta Med Iran 2011;49(9):619-24. PMID: 22052146

Therapy

Fibronectin and Periostin as Prognostic Markers in Ovarian Cancer.
Kujawa KA, Zembala-Nożyńska E, Cortez AJ, Kujawa T, Kupryjańczyk J, Lisowska KM
Cells 2020 Jan 8;9(1) doi: 10.3390/cells9010149. PMID: 31936272Free PMC Article
Ovarian preservation for low-grade endometrial stromal sarcoma: a systematic review of the literature and meta-analysis.
Nasioudis D, Ko EM, Kolovos G, Vagios S, Kalliouris D, Giuntoli RL
Int J Gynecol Cancer 2019 Jan;29(1):126-132. doi: 10.1136/ijgc-2018-000063. PMID: 30640694
Estrogen therapy in gynecological cancer survivors.
Guidozzi F
Climacteric 2013 Dec;16(6):611-7. Epub 2013 Aug 16 doi: 10.3109/13697137.2013.806471. PMID: 23952524
Menopause, hormone replacement and gynaecological cancers.
Hinds L, Price J
Menopause Int 2010 Jun;16(2):89-93. doi: 10.1258/mi.2010.010018. PMID: 20729501
Fertility-sparing surgery for malignancies in women.
Gershenson DM
J Natl Cancer Inst Monogr 2005;(34):43-7. doi: 10.1093/jncimonographs/lgi011. PMID: 15784822

Prognosis

Prognosis of uterine and extrauterine low-grade endometrial stromal sarcoma: an observational cohort study.
Dai Q, Xu B, Wu H, You Y, Li L
Int J Surg 2024 Apr 1;110(4):1919-1928. doi: 10.1097/JS9.0000000000001146. PMID: 38329091Free PMC Article
Endometrial stromal tumors of the uterus: Epidemiology, pathological and biological features, treatment options and clinical outcomes.
Gadducci A, Multinu F, De Vitis LA, Cosio S, Carinelli S, Aletti GD
Gynecol Oncol 2023 Apr;171:95-105. Epub 2023 Feb 24 doi: 10.1016/j.ygyno.2023.02.009. PMID: 36842409
Endometrioid Borderline Ovarian Tumor: Clinical Characteristics, Prognosis, and Managements.
Ricotta G, Maulard A, Candiani M, Scherrier S, Genestie C, Pautier P, Leary A, Chargari C, Mangili G, Morice P, Gouy S
Ann Surg Oncol 2022 Sep;29(9):5894-5903. Epub 2022 May 19 doi: 10.1245/s10434-022-11893-7. PMID: 35590116
The prognosis of recurrent low-grade endometrial stromal sarcoma: a retrospective cohort study.
Dai Q, Xu B, Wu H, You Y, Wu M, Li L
Orphanet J Rare Dis 2021 Apr 7;16(1):160. doi: 10.1186/s13023-021-01802-8. PMID: 33827628Free PMC Article
Prognostic factors of synchronous endometrial and ovarian endometrioid carcinoma.
Yoneoka Y, Yoshida H, Ishikawa M, Shimizu H, Uehara T, Murakami T, Kato T
J Gynecol Oncol 2019 Jan;30(1):e7. Epub 2018 Sep 17 doi: 10.3802/jgo.2019.30.e7. PMID: 30479091Free PMC Article

Clinical prediction guides

Prognosis of uterine and extrauterine low-grade endometrial stromal sarcoma: an observational cohort study.
Dai Q, Xu B, Wu H, You Y, Li L
Int J Surg 2024 Apr 1;110(4):1919-1928. doi: 10.1097/JS9.0000000000001146. PMID: 38329091Free PMC Article
Primary ovarian endometrioid stromal sarcoma presenting with reno-ureteral colic.
Moral AIB, Jiménez JCV, Bañón CM, Díaz Huesca MJ, González MV, López JSJ
BMC Womens Health 2022 Dec 3;22(1):491. doi: 10.1186/s12905-022-02046-9. PMID: 36463169Free PMC Article
Endometrioid Borderline Ovarian Tumor: Clinical Characteristics, Prognosis, and Managements.
Ricotta G, Maulard A, Candiani M, Scherrier S, Genestie C, Pautier P, Leary A, Chargari C, Mangili G, Morice P, Gouy S
Ann Surg Oncol 2022 Sep;29(9):5894-5903. Epub 2022 May 19 doi: 10.1245/s10434-022-11893-7. PMID: 35590116
Ovarian preservation for low-grade endometrial stromal sarcoma: a systematic review of the literature and meta-analysis.
Nasioudis D, Ko EM, Kolovos G, Vagios S, Kalliouris D, Giuntoli RL
Int J Gynecol Cancer 2019 Jan;29(1):126-132. doi: 10.1136/ijgc-2018-000063. PMID: 30640694
Prognostic factors of synchronous endometrial and ovarian endometrioid carcinoma.
Yoneoka Y, Yoshida H, Ishikawa M, Shimizu H, Uehara T, Murakami T, Kato T
J Gynecol Oncol 2019 Jan;30(1):e7. Epub 2018 Sep 17 doi: 10.3802/jgo.2019.30.e7. PMID: 30479091Free PMC Article

Recent systematic reviews

Uterine lesions with sex cord-like architectures: a systematic review.
Jia M, Sun PL, Gao H
Diagn Pathol 2019 Nov 18;14(1):129. doi: 10.1186/s13000-019-0909-y. PMID: 31739799Free PMC Article
Ovarian preservation for low-grade endometrial stromal sarcoma: a systematic review of the literature and meta-analysis.
Nasioudis D, Ko EM, Kolovos G, Vagios S, Kalliouris D, Giuntoli RL
Int J Gynecol Cancer 2019 Jan;29(1):126-132. doi: 10.1136/ijgc-2018-000063. PMID: 30640694
Clinical characteristics and outcomes of uterine tumors resembling ovarian sex-cord tumors (UTROSCT): a systematic review of literature.
Blake EA, Sheridan TB, Wang KL, Takiuchi T, Kodama M, Sawada K, Matsuo K
Eur J Obstet Gynecol Reprod Biol 2014 Oct;181:163-70. Epub 2014 Aug 8 doi: 10.1016/j.ejogrb.2014.07.050. PMID: 25150955

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...