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Mediastinal soft tissue cancer

MedGen UID:: 277335
•Concept ID:: C1334599
•: Neoplastic Process

Synonyms:	malignant mediastinal mesenchymal tumor; malignant mediastinal mesenchymal tumour; Malignant Mediastinal Soft Tissue Neoplasm; malignant mediastinal soft tissue neoplasm; Malignant Mediastinal Soft Tissue Tumor; malignant mediastinal soft tissue tumor; malignant mediastinal soft tissue tumour; Malignant Soft Tissue Neoplasm of Mediastinum; malignant soft tissue neoplasm of mediastinum; Malignant Soft Tissue Neoplasm of the Mediastinum; malignant soft tissue neoplasm of the mediastinum; Malignant Soft Tissue Tumor of Mediastinum; malignant soft tissue tumor of mediastinum; Malignant Soft Tissue Tumor of the Mediastinum; malignant soft tissue tumor of the mediastinum; malignant soft tissue tumour of mediastinum; malignant soft tissue tumour of the mediastinum; mediastinal mesenchymal tumor, malignant; mediastinal soft tissue cancer

Monarch Initiative:	MONDO:0037743

Definition

A malignant mesenchymal neoplasm that arises from the mediastinum. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVMediastinal soft tissue cancer

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Neoplasm
      - Malignant neoplastic disease
        Malignant soft tissue neoplasm
        Mediastinal soft tissue cancer
        Mediastinal Epithelioid Hemangioendothelioma
        Mediastinum sarcoma
        Mediastinal extraskeletal osteosarcoma
        Mediastinal Malignant Peripheral Nerve Sheath Tumor
        Malignant melanocytic peripheral nerve sheath tumor of mediastinum
        Mediastinum angiosarcoma
        Mediastinum leiomyosarcoma
        Mediastinum liposarcoma
        Thymoliposarcoma
        Mediastinum rhabdomyosarcoma
        Mediastinum synovial sarcoma

Professional guidelines

PubMed

Current topics and management of head and neck sarcomas.

Kobayashi K, Hanai N, Yoshimoto S, Saito Y, Homma A
Jpn J Clin Oncol 2023 Aug 30;53(9):743-756. doi: 10.1093/jjco/hyad048. PMID: 37309253 Free PMC Article

MRI-Based Stepwise Approach to Anterior Mediastinal Cystic Lesions for Diagnosis and Further Management.

Kim JH, Choe J, Kim HK, Lee HY
Korean J Radiol 2023 Jan;24(1):62-78. doi: 10.3348/kjr.2022.0606. PMID: 36606621 Free PMC Article

Management of desmoplastic small round cell tumor.

Hayes-Jordan A, LaQuaglia MP, Modak S
Semin Pediatr Surg 2016 Oct;25(5):299-304. Epub 2016 Sep 14 doi: 10.1053/j.sempedsurg.2016.09.005. PMID: 27955733 Free PMC Article

See all (18)

Recent clinical studies

Etiology

Cancer and Atrial Fibrillation Comorbidities Among 25 Million Citizens in Shanghai, China: Medical Insurance Database Study.

Chen M, Li C, Zhang J, Cui X, Tian W, Liao P, Wang Q, Sun J, Luo L, Wu H, Li YG
JMIR Public Health Surveill 2023 Oct 17;9:e40149. doi: 10.2196/40149. PMID: 37847541 Free PMC Article

Mediastinal and subglottic hemangioma in an infant: a case report and literature review.

Lin Q, Hai Y, Chen S, Feng N, Mo Z, Wei Y, Luo Q, Huang X, Fan L, Chen J, Xiang W
J Int Med Res 2021 Aug;49(8):3000605211039803. doi: 10.1177/03000605211039803. PMID: 34459273 Free PMC Article

What's new in adipocytic neoplasia?

Creytens D
Virchows Arch 2020 Jan;476(1):29-39. Epub 2019 Sep 9 doi: 10.1007/s00428-019-02652-3. PMID: 31501988

Pediatric Non-vestibular Schwannoma.

Broehm C, Al-Ibraheemi A, Fritchie KJ
Pediatr Dev Pathol 2017 Jun;20(3):232-239. Epub 2017 Apr 18 doi: 10.1177/1093526617703540. PMID: 28420320

Primary thoracic sarcomas.

Gladish GW, Sabloff BM, Munden RF, Truong MT, Erasmus JJ, Chasen MH
Radiographics 2002 May-Jun;22(3):621-37. doi: 10.1148/radiographics.22.3.g02ma17621. PMID: 12006691

See all (206)

Diagnosis

Current topics and management of head and neck sarcomas.

Kobayashi K, Hanai N, Yoshimoto S, Saito Y, Homma A
Jpn J Clin Oncol 2023 Aug 30;53(9):743-756. doi: 10.1093/jjco/hyad048. PMID: 37309253 Free PMC Article

A review on pulmonary and mediastinal synovial sarcoma.

Dewi KP, Dewi IP, Iswanto I, Wulandari L
J Basic Clin Physiol Pharmacol 2023 Mar 1;34(2):169-175. Epub 2023 Feb 20 doi: 10.1515/jbcpp-2022-0286. PMID: 36800987

Spindle cell tumors of the mediastinum.

Suster D
Ann Diagn Pathol 2022 Oct;60:152018. Epub 2022 Jul 22 doi: 10.1016/j.anndiagpath.2022.152018. PMID: 35908333

What's new in adipocytic neoplasia?

Creytens D
Virchows Arch 2020 Jan;476(1):29-39. Epub 2019 Sep 9 doi: 10.1007/s00428-019-02652-3. PMID: 31501988

Liposarcoma.

Springfield D
Clin Orthop Relat Res 1993 Apr;(289):50-7. PMID: 8472432

See all (608)

Therapy

PET/CT: Clinical role in lymphomas.

Papathanasiou N
Hell J Nucl Med 2023 May-Aug;26 Suppl:36-37. PMID: 37658560

Mediastinal and subglottic hemangioma in an infant: a case report and literature review.

Lin Q, Hai Y, Chen S, Feng N, Mo Z, Wei Y, Luo Q, Huang X, Fan L, Chen J, Xiang W
J Int Med Res 2021 Aug;49(8):3000605211039803. doi: 10.1177/03000605211039803. PMID: 34459273 Free PMC Article

Management Strategies for Patients With Epithelioid Hemangioendothelioma: Charting an Indolent Disease Course.

Yurkiewicz IR, Zhou M, Ganjoo KN, Charville GW, Bolleddu S, Lohman M, Bui N
Am J Clin Oncol 2021 Aug 1;44(8):419-422. doi: 10.1097/COC.0000000000000827. PMID: 34028371

Management of desmoplastic small round cell tumor.

Hayes-Jordan A, LaQuaglia MP, Modak S
Semin Pediatr Surg 2016 Oct;25(5):299-304. Epub 2016 Sep 14 doi: 10.1053/j.sempedsurg.2016.09.005. PMID: 27955733 Free PMC Article

Liposarcoma.

Springfield D
Clin Orthop Relat Res 1993 Apr;(289):50-7. PMID: 8472432

See all (110)

Prognosis

PET/CT: Clinical role in lymphomas.

Papathanasiou N
Hell J Nucl Med 2023 May-Aug;26 Suppl:36-37. PMID: 37658560

What's new in adipocytic neoplasia?

Creytens D
Virchows Arch 2020 Jan;476(1):29-39. Epub 2019 Sep 9 doi: 10.1007/s00428-019-02652-3. PMID: 31501988

Pediatric Non-vestibular Schwannoma.

Broehm C, Al-Ibraheemi A, Fritchie KJ
Pediatr Dev Pathol 2017 Jun;20(3):232-239. Epub 2017 Apr 18 doi: 10.1177/1093526617703540. PMID: 28420320

Liposarcoma.

Springfield D
Clin Orthop Relat Res 1993 Apr;(289):50-7. PMID: 8472432

Thymoma: radiologic-pathologic correlation.

Rosado-de-Christenson ML, Galobardes J, Moran CA
Radiographics 1992 Jan;12(1):151-68. doi: 10.1148/radiographics.12.1.1734461. PMID: 1734461

See all (240)

Clinical prediction guides

Cancer and Atrial Fibrillation Comorbidities Among 25 Million Citizens in Shanghai, China: Medical Insurance Database Study.

Chen M, Li C, Zhang J, Cui X, Tian W, Liao P, Wang Q, Sun J, Luo L, Wu H, Li YG
JMIR Public Health Surveill 2023 Oct 17;9:e40149. doi: 10.2196/40149. PMID: 37847541 Free PMC Article

PET/CT: Clinical role in lymphomas.

Papathanasiou N
Hell J Nucl Med 2023 May-Aug;26 Suppl:36-37. PMID: 37658560

Cutaneous Myoepithelial Neoplasms on Acral Sites Show Distinctive and Reproducible Histopathologic and Immunohistochemical Features.

Mehta A, Davey J, Gharpuray-Pandit D, Plaza JA, Billings SD, Balogh P, Tchrakian N, Selvan S, Wiedemeyer K, Hornick JL, Brenn T
Am J Surg Pathol 2022 Sep 1;46(9):1241-1249. Epub 2022 Mar 31 doi: 10.1097/PAS.0000000000001896. PMID: 35354162

Dumbbell-Mimicked Mediastinal Angiomatosis.

Tang EK, Chu PT, Goan YG, Hsieh PP, Lin JC
Ann Thorac Surg 2016 Dec;102(6):e555-e556. doi: 10.1016/j.athoracsur.2016.05.051. PMID: 27847080

Thoracic lymphoma.

North LB, Libshitz HI, Lorigan JG
Radiol Clin North Am 1990 Jul;28(4):745-62. PMID: 2190268

See all (124)

Recent systematic reviews

Prevalence, clinical characteristics, and management of silicone lymphadenopathy: A systematic review of the literature.

Pelegrina Perez TC, Desai A, Tadisina KK, Singh DP, Kesmodel SB, Rojas KE, Mella-Catinchi JR
J Plast Reconstr Aesthet Surg 2024 Mar;90:76-87. Epub 2024 Feb 1 doi: 10.1016/j.bjps.2024.01.011. PMID: 38364672

Cervical necrotizing fasciitis: Systematic review and analysis of 1235 reported cases from the literature.

Gunaratne DA, Tseros EA, Hasan Z, Kudpaje AS, Suruliraj A, Smith MC, Riffat F, Palme CE
Head Neck 2018 Sep;40(9):2094-2102. Epub 2018 Jun 22 doi: 10.1002/hed.25184. PMID: 29934952

The role of positron emission tomography using carbon-11 and fluorine-18 choline in tumors other than prostate cancer: a systematic review.

Treglia G, Giovannini E, Di Franco D, Calcagni ML, Rufini V, Picchio M, Giordano A
Ann Nucl Med 2012 Jul;26(6):451-61. Epub 2012 May 8 doi: 10.1007/s12149-012-0602-7. PMID: 22566040

See all (3)

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Mediastinal soft tissue cancer

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

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Table of contents

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Practice guidelines

Consumer resources

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