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Testicular yolk sac tumor, papillary pattern

MedGen UID:
308262
•Concept ID:
C1515310
•
Neoplastic Process
Synonyms: papillary pattern testicular yolk sac tumor; papillary pattern testicular yolk sac tumour; Testicular Yolk Sac Tumor, Papillary Pattern; testicular yolk sac tumor, papillary pattern
 
Monarch Initiative: MONDO:0004493

Definition

A yolk sac tumor that arises from the testis and is characterized by the presence of numerous papillary structures that are lined by cells with prominent nucleoli. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTesticular yolk sac tumor, papillary pattern

Recent clinical studies

Etiology

Yolk Sac Tumor of the Testis in Infants and Children: A Clinicopathologic Analysis of 33 Cases.
Cornejo KM, Frazier L, Lee RS, Kozakewich HP, Young RH
Am J Surg Pathol 2015 Aug;39(8):1121-31. doi: 10.1097/PAS.0000000000000432. PMID: 25828390
Cytodiagnosis of yolk sac tumor.
Afroz N, Khan N, Chana RS
Indian J Pediatr 2004 Oct;71(10):939-42. doi: 10.1007/BF02830842. PMID: 15531841
Histochemically demonstrable changes in cell surface carbohydrates of human germ cell tumors.
Teshima S, Hirohashi S, Shimosato Y, Kishi K, Ino Y, Matsumoto K, Yamada T
Lab Invest 1984 Mar;50(3):271-7. PMID: 6321856

Diagnosis

Pure post-pubertal yolk sac tumor of the testis: An extremely rare and aggressive entity.
Patel S, Satturwar S, Khan W, Ashman D, Quiroga-Garza GM
Ann Diagn Pathol 2023 Apr;63:152086. Epub 2022 Dec 23 doi: 10.1016/j.anndiagpath.2022.152086. PMID: 36580878
Yolk Sac Tumor of the Testis in Infants and Children: A Clinicopathologic Analysis of 33 Cases.
Cornejo KM, Frazier L, Lee RS, Kozakewich HP, Young RH
Am J Surg Pathol 2015 Aug;39(8):1121-31. doi: 10.1097/PAS.0000000000000432. PMID: 25828390
The yolk sac tumor: reflections on a remarkable neoplasm and two of the many intrigued by it-Gunnar Teilum and Aleksander Talerman-and the bond it formed between them.
Young RH
Int J Surg Pathol 2014 Dec;22(8):677-87. Epub 2014 Nov 12 doi: 10.1177/1066896914558265. PMID: 25395492
Testicular embryonal carcinoma: a morphologic study of 180 cases highlighting unusual and unemphasized aspects.
Kao CS, Ulbright TM, Young RH, Idrees MT
Am J Surg Pathol 2014 May;38(5):689-97. doi: 10.1097/PAS.0000000000000171. PMID: 24503753
Cytodiagnosis of yolk sac tumor.
Afroz N, Khan N, Chana RS
Indian J Pediatr 2004 Oct;71(10):939-42. doi: 10.1007/BF02830842. PMID: 15531841

Prognosis

Juvenile granulosa cell tumors of the testis: a clinicopathologic study of 70 cases with emphasis on its wide morphologic spectrum.
Kao CS, Cornejo KM, Ulbright TM, Young RH
Am J Surg Pathol 2015 Sep;39(9):1159-69. doi: 10.1097/PAS.0000000000000450. PMID: 26076062
Yolk Sac Tumor of the Testis in Infants and Children: A Clinicopathologic Analysis of 33 Cases.
Cornejo KM, Frazier L, Lee RS, Kozakewich HP, Young RH
Am J Surg Pathol 2015 Aug;39(8):1121-31. doi: 10.1097/PAS.0000000000000432. PMID: 25828390

Clinical prediction guides

Juvenile granulosa cell tumors of the testis: a clinicopathologic study of 70 cases with emphasis on its wide morphologic spectrum.
Kao CS, Cornejo KM, Ulbright TM, Young RH
Am J Surg Pathol 2015 Sep;39(9):1159-69. doi: 10.1097/PAS.0000000000000450. PMID: 26076062
Yolk Sac Tumor of the Testis in Infants and Children: A Clinicopathologic Analysis of 33 Cases.
Cornejo KM, Frazier L, Lee RS, Kozakewich HP, Young RH
Am J Surg Pathol 2015 Aug;39(8):1121-31. doi: 10.1097/PAS.0000000000000432. PMID: 25828390

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