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Vulvar Congenital Melanocytic Nevus

MedGen UID:
311485
•Concept ID:
C1520077
•
Neoplastic Process

Definition

A benign nevus that arises from the vulva and is present at birth. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVulvar Congenital Melanocytic Nevus

Recent clinical studies

Etiology

Acquired melanocytic naevus in childhood vulval pemphigoid.
Lebeau S, Braun RP, Masouyé I, Perrinaud A, Harms M, Borradori L
Dermatology 2006;213(2):159-62. doi: 10.1159/000093859. PMID: 16902297
Lessons on dermoscopy #8. A high-risk melanocytic lesion.
Johr RH, Schachner LA, Izakovic J
Dermatol Surg 2000 Sep;26(9):893-5. doi: 10.1046/j.1524-4725.2000.00102.x. PMID: 10971568

Diagnosis

A successfully treated malignant melanoma arising in a large congenital vulvar blue nevus.
Lin W, Song P, Ran X, Li R, Jiang X
Dermatol Ther 2020 Nov;33(6):e13821. Epub 2020 Jul 13 doi: 10.1111/dth.13821. PMID: 32531081
Late-onset bulky naevocytoma of the perineum masquerading as a malignant melanoma.
Huh JW, Yoo J, Kim MS, Choi KH, Jue MS, Park HJ
Clin Exp Dermatol 2017 Mar;42(2):178-181. Epub 2016 Nov 15 doi: 10.1111/ced.12971. PMID: 27862168
Acquired melanocytic naevus in childhood vulval pemphigoid.
Lebeau S, Braun RP, Masouyé I, Perrinaud A, Harms M, Borradori L
Dermatology 2006;213(2):159-62. doi: 10.1159/000093859. PMID: 16902297
Lessons on dermoscopy #8. A high-risk melanocytic lesion.
Johr RH, Schachner LA, Izakovic J
Dermatol Surg 2000 Sep;26(9):893-5. doi: 10.1046/j.1524-4725.2000.00102.x. PMID: 10971568

Therapy

Life-threatening blood loss from scratching provoked by pruritus in the bulky perineal nevocytoma variant of giant congenital melanocytic nevus in a child.
Feng J, Sethi A, Reyes-Múgica M, Antaya R
J Am Acad Dermatol 2005 Aug;53(2 Suppl 1):S139-42. doi: 10.1016/j.jaad.2004.12.040. PMID: 16021164

Prognosis

Acquired melanocytic naevus in childhood vulval pemphigoid.
Lebeau S, Braun RP, Masouyé I, Perrinaud A, Harms M, Borradori L
Dermatology 2006;213(2):159-62. doi: 10.1159/000093859. PMID: 16902297

Clinical prediction guides

A successfully treated malignant melanoma arising in a large congenital vulvar blue nevus.
Lin W, Song P, Ran X, Li R, Jiang X
Dermatol Ther 2020 Nov;33(6):e13821. Epub 2020 Jul 13 doi: 10.1111/dth.13821. PMID: 32531081
Acquired melanocytic naevus in childhood vulval pemphigoid.
Lebeau S, Braun RP, Masouyé I, Perrinaud A, Harms M, Borradori L
Dermatology 2006;213(2):159-62. doi: 10.1159/000093859. PMID: 16902297

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