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Nasopharyngeal Paraganglioma

MedGen UID:
313474
•Concept ID:
C1709154
•
Neoplastic Process

Definition

An extra-adrenal paraganglioma arising from the nasopharynx and nose. Epistaxis or nasal obstruction are common presenting symptoms. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNasopharyngeal Paraganglioma

Professional guidelines

PubMed

Imaging Evaluation and Treatment of Vascular Lesions at the Skull Base.
Jindal G, Miller T, Raghavan P, Gandhi D
Radiol Clin North Am 2017 Jan;55(1):151-166. Epub 2016 Oct 25 doi: 10.1016/j.rcl.2016.08.003. PMID: 27890183
The Differential Diagnosis of Sinonasal/Nasopharyngeal Neuroendocrine/Neuroectodermally Derived Tumors.
Montone KT
Arch Pathol Lab Med 2015 Dec;139(12):1498-507. doi: 10.5858/arpa.2014-0383-RA. PMID: 26619022
Non-paraganglioma tumors of the jugular foramen - Growth patterns, radiological presentation, differential diagnosis.
Szymańska A, Szymański M, Czekajska-Chehab E, Szczerbo-Trojanowska M
Neurol Neurochir Pol 2015;49(3):156-63. Epub 2015 Apr 23 doi: 10.1016/j.pjnns.2015.04.003. PMID: 26048603

Recent clinical studies

Diagnosis

Multiple paraganglioma syndrome type 4 due to succinate dehydrogenase B mutation: diagnostic and therapeutic challenges of a skull base paraganglioma masquerading as nasopharyngeal cancer.
Alzahrani AS, Alshaikh O, Faiyaz-Ul-Haque M, Abalkhail H, Al-Dayel F, Hindi HA
Endocr Pract 2010 May-Jun;16(3):452-8. doi: 10.4158/EP09315.CR. PMID: 20061288
Hereditary paraganglioma of the nasopharynx.
Said-Al-Naief N, Ojha J
Head Neck Pathol 2008 Dec;2(4):272-8. Epub 2008 Nov 9 doi: 10.1007/s12105-008-0090-1. PMID: 20614293Free PMC Article
Primary nasopharyngeal paraganglioma: a case report.
Kanoh N, Nishimura Y, Nakamura M, Mori M, Uematsu K
Auris Nasus Larynx 1991;18(3):307-14. doi: 10.1016/s0385-8146(12)80267-7. PMID: 1799335
Nasal and nasopharyngeal paraganglioma.
Kuhn JA, Aronoff BL
J Surg Oncol 1989 Jan;40(1):38-45. doi: 10.1002/jso.2930400110. PMID: 2642567

Therapy

Multiple paraganglioma syndrome type 4 due to succinate dehydrogenase B mutation: diagnostic and therapeutic challenges of a skull base paraganglioma masquerading as nasopharyngeal cancer.
Alzahrani AS, Alshaikh O, Faiyaz-Ul-Haque M, Abalkhail H, Al-Dayel F, Hindi HA
Endocr Pract 2010 May-Jun;16(3):452-8. doi: 10.4158/EP09315.CR. PMID: 20061288

Prognosis

Multiple paraganglioma syndrome type 4 due to succinate dehydrogenase B mutation: diagnostic and therapeutic challenges of a skull base paraganglioma masquerading as nasopharyngeal cancer.
Alzahrani AS, Alshaikh O, Faiyaz-Ul-Haque M, Abalkhail H, Al-Dayel F, Hindi HA
Endocr Pract 2010 May-Jun;16(3):452-8. doi: 10.4158/EP09315.CR. PMID: 20061288
Primary nasopharyngeal paraganglioma: a case report.
Kanoh N, Nishimura Y, Nakamura M, Mori M, Uematsu K
Auris Nasus Larynx 1991;18(3):307-14. doi: 10.1016/s0385-8146(12)80267-7. PMID: 1799335

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