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Disorder of pharynx

MedGen UID:: 10691
•Concept ID:: C0031345
•: Disease or Syndrome

Synonyms:	Disease, Pharyngeal; Disease, Pharynx; Diseases of Pharynx; Diseases, Pharyngeal; Diseases, Pharynx; Pharyngeal Disease; Pharyngeal Diseases; Pharynx Disease; Pharynx Diseases
SNOMED CT:	Disorder of pharynx (75860007)

Definition

A non-neoplastic or neoplastic disorder that affects the pharynx. Representative examples include pharyngitis and carcinoma. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVDisorder of pharynx

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Disorder by Site
      - Head and Neck Disorder
        Disorder of neck
        Disorder of pharynx
        Dysphagia
        Dyskinesia of esophagus
        Achalasia
        CREST syndrome
        Esophageal spasms
        Gastroesophageal reflux disease
        Plummer-Vinson syndrome
        Esophageal dysphagia
        Impaired oral bolus formation
        Impaired oropharyngeal swallow response
        Neuromuscular dysphagia
        Oral-pharyngeal dysphagia
        Lemierre syndrome
        Nasopharyngeal disorder
        Nasopharyngeal Non-Neoplastic Disorder
        Nasopharyngeal Hairy Polyp
        Nasopharyngeal Salivary Gland Anlage Tumor
        Nasopharyngitis
        Neoplasia of the nasopharynx
        Benign neoplasm of nasopharynx
        Malignant Nasopharyngeal Neoplasm
        Nasopharyngeal carcinoma
        Nasopharyngeal Paraganglioma
        Nasopharyngeal Pituitary Neuroendocrine Tumor
        Neoplasm of the nose
        Neoplasm of the pharynx
        Non-Neoplastic Pharyngeal Disorder
        Epiglottitis
        Pharyngeal Mucositis
        Pharyngitis
        Acute pharyngitis
        Recurrent pharyngitis
        Retropharyngeal abscess
        Streptococcal sore throat
        Tonsillitis
        Tonsillopharyngitis
        Velopharyngeal insufficiency

Professional guidelines

PubMed

HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management.

Lechner M, Liu J, Masterson L, Fenton TR
Nat Rev Clin Oncol 2022 May;19(5):306-327. Epub 2022 Feb 1 doi: 10.1038/s41571-022-00603-7. PMID: 35105976 Free PMC Article

Diagnostic Methods, Clinical Guidelines, and Antibiotic Treatment for Group A Streptococcal Pharyngitis: A Narrative Review.

Mustafa Z, Ghaffari M
Front Cell Infect Microbiol 2020;10:563627. Epub 2020 Oct 15 doi: 10.3389/fcimb.2020.563627. PMID: 33178623 Free PMC Article

Pharyngitis: Approach to diagnosis and treatment.

Sykes EA, Wu V, Beyea MM, Simpson MTW, Beyea JA
Can Fam Physician 2020 Apr;66(4):251-257. PMID: 32273409 Free PMC Article

See all (4328)

Recent clinical studies

Etiology

Analysis of the Clinical Features and Surgical Outcomes of First Branchial Cleft Anomalies.

Yang R, Dong C, Chen Y, Liu H, Zhang C, Lai Y, Zha D, Han Y
Laryngoscope 2022 May;132(5):1008-1014. Epub 2021 Oct 7 doi: 10.1002/lary.29896. PMID: 34617600

Reconstruction after salvage laryngectomy.

Yeh DH, Sahovaler A, Fung K
Oral Oncol 2017 Dec;75:22-27. Epub 2017 Oct 21 doi: 10.1016/j.oraloncology.2017.10.009. PMID: 29224818

Deep neck infections.

Conrad DE, Parikh SR
Infect Disord Drug Targets 2012 Aug;12(4):286-90. doi: 10.2174/187152612801319348. PMID: 22338590

Oropharyngeal histoplasmosis: report of eleven cases and review of the literature.

Antonello VS, Zaltron VF, Vial M, Oliveira FM, Severo LC
Rev Soc Bras Med Trop 2011 Jan-Feb;44(1):26-9. doi: 10.1590/s0037-86822011000100007. PMID: 21340403

Pharyngocutaneous fistula.

Mäkitie AA, Irish J, Gullane PJ
Curr Opin Otolaryngol Head Neck Surg 2003 Apr;11(2):78-84. doi: 10.1097/00020840-200304000-00003. PMID: 14515083

See all (28715)

Diagnosis

The Underestimated Role of Mast Cells in the Pathogenesis of Rhinopathies.

Gelardi M, Giancaspro R, Cassano M, Ribatti D
Int Arch Allergy Immunol 2022;183(2):153-159. Epub 2021 Sep 22 doi: 10.1159/000518924. PMID: 34551414

Glossopharyngeal neuralgia.

Blumenfeld A, Nikolskaya G
Curr Pain Headache Rep 2013 Jul;17(7):343. doi: 10.1007/s11916-013-0343-x. PMID: 23709235

Laryngopharyngeal reflux.

Franco RA Jr
Allergy Asthma Proc 2006 Jan-Feb;27(1):21-5. PMID: 16598989

Pharyngocutaneous fistula.

Mäkitie AA, Irish J, Gullane PJ
Curr Opin Otolaryngol Head Neck Surg 2003 Apr;11(2):78-84. doi: 10.1097/00020840-200304000-00003. PMID: 14515083

Throat disorders.

Berger MS
Prim Care 1998 Sep;25(3):685-99. doi: 10.1016/s0095-4543(15)30009-9. PMID: 9673327

See all (24888)

Therapy

Role of Exosomes in Pharyngucutaneous Fistula After Total Laryngectomy.

Chen L, Wang M, Zhong Z, Liu B, Zhang W, Zhu B, Jiao C, Yu C, Guan B
Int J Nanomedicine 2022;17:4119-4135. Epub 2022 Sep 12 doi: 10.2147/IJN.S372042. PMID: 36118178 Free PMC Article

Role of steroids in conservative treatment of parapharyngeal and retropharyngeal abscess in children.

Villanueva-Fernández E, Casanueva-Muruáis R, Vivanco-Allende A, Llorente JL, Coca-Pelaz A
Eur Arch Otorhinolaryngol 2022 Nov;279(11):5331-5338. Epub 2022 Jun 29 doi: 10.1007/s00405-022-07423-6. PMID: 35767057 Free PMC Article

Prevention and management of treatment-induced pharyngo-oesophageal stricture.

Prisman E, Miles BA, Genden EM
Lancet Oncol 2013 Aug;14(9):e380-6. doi: 10.1016/S1470-2045(13)70160-8. PMID: 23896277

Globus pharyngeus: a review of its etiology, diagnosis and treatment.

Lee BE, Kim GH
World J Gastroenterol 2012 May 28;18(20):2462-71. doi: 10.3748/wjg.v18.i20.2462. PMID: 22654443 Free PMC Article

Oropharyngeal histoplasmosis: report of eleven cases and review of the literature.

Antonello VS, Zaltron VF, Vial M, Oliveira FM, Severo LC
Rev Soc Bras Med Trop 2011 Jan-Feb;44(1):26-9. doi: 10.1590/s0037-86822011000100007. PMID: 21340403

See all (18881)

Prognosis

Risk Factors for Dysphagia in ICU Patients After Invasive Mechanical Ventilation.

Zuercher P, Schenk NV, Moret C, Berger D, Abegglen R, Schefold JC
Chest 2020 Nov;158(5):1983-1991. Epub 2020 Jun 7 doi: 10.1016/j.chest.2020.05.576. PMID: 32525018

Congenital Neck Masses.

Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417

Second branchial cleft anomalies in children: a literature review.

Shen LF, Zhou SH, Chen QQ, Yu Q
Pediatr Surg Int 2018 Dec;34(12):1251-1256. Epub 2018 Sep 24 doi: 10.1007/s00383-018-4348-8. PMID: 30251021

Globus pharyngeus: a review of etiology, diagnostics, and treatment.

Järvenpää P, Arkkila P, Aaltonen LM
Eur Arch Otorhinolaryngol 2018 Aug;275(8):1945-1953. Epub 2018 Jun 25 doi: 10.1007/s00405-018-5041-1. PMID: 29943257

Pharyngocutaneous fistula.

Mäkitie AA, Irish J, Gullane PJ
Curr Opin Otolaryngol Head Neck Surg 2003 Apr;11(2):78-84. doi: 10.1097/00020840-200304000-00003. PMID: 14515083

See all (18266)

Clinical prediction guides

Elucidating inconsistencies in dysphagia diagnostics: Redefining normal.

Plowman EK, Humbert IA
Int J Speech Lang Pathol 2018 Jun;20(3):310-317. Epub 2018 May 3 doi: 10.1080/17549507.2018.1461931. PMID: 29724130

Insights Into Oropharyngeal Dysphagia From Administrative Data and Clinical Registries: A Literature Review.

Bartlett RS, Thibeault SL
Am J Speech Lang Pathol 2018 May 3;27(2):868-883. doi: 10.1044/2018_AJSLP-17-0158. PMID: 29710238 Free PMC Article

Poor consistency in evaluating South African adults with neurogenic dysphagia.

Andrews M, Pillay M
S Afr J Commun Disord 2017 Jan 23;64(1):e1-e14. doi: 10.4102/sajcd.v64i1.158. PMID: 28155280 Free PMC Article

An appraisal of current dysphagia diagnosis and treatment strategies.

Kaindlstorfer A, Pointner R
Expert Rev Gastroenterol Hepatol 2016 Aug;10(8):929-42. Epub 2016 Mar 16 doi: 10.1586/17474124.2016.1158098. PMID: 26906944

Dysphagia bedside screening for acute-stroke patients: the Gugging Swallowing Screen.

Trapl M, Enderle P, Nowotny M, Teuschl Y, Matz K, Dachenhausen A, Brainin M
Stroke 2007 Nov;38(11):2948-52. Epub 2007 Sep 20 doi: 10.1161/STROKEAHA.107.483933. PMID: 17885261

See all (15871)

Recent systematic reviews

Screening for aspiration risk associated with dysphagia in acute stroke.

Boaden E, Burnell J, Hives L, Dey P, Clegg A, Lyons MW, Lightbody CE, Hurley MA, Roddam H, McInnes E, Alexandrov A, Watkins CL
Cochrane Database Syst Rev 2021 Oct 18;10(10):CD012679. doi: 10.1002/14651858.CD012679.pub2. PMID: 34661279 Free PMC Article

Consensus on the treatment of dysphagia in Parkinson's disease.

Schindler A, Pizzorni N, Cereda E, Cosentino G, Avenali M, Montomoli C, Abbruzzese G, Antonini A, Barbiera F, Benazzo M, Benarroch E, Bertino G, Clavè P, Cortelli P, Eleopra R, Ferrari C, Hamdy S, Huckabee ML, Lopiano L, Marchese-Ragona R, Masiero S, Michou E, Occhini A, Pacchetti C, Pfeiffer RF, Restivo DA, Rondanelli M, Ruoppolo G, Sandrini G, Schapira A, Stocchi F, Tolosa E, Valentino F, Zamboni M, Zangaglia R, Zappia M, Tassorelli C, Alfonsi E
J Neurol Sci 2021 Nov 15;430:120008. Epub 2021 Sep 27 doi: 10.1016/j.jns.2021.120008. PMID: 34624796

Effectiveness of Neuromuscular Electrical Stimulation on Post-Stroke Dysphagia: A Systematic Review of Randomized Controlled Trials.

Alamer A, Melese H, Nigussie F
Clin Interv Aging 2020;15:1521-1531. Epub 2020 Sep 3 doi: 10.2147/CIA.S262596. PMID: 32943855 Free PMC Article

Corticosteroids for treatment of sore throat: systematic review and meta-analysis of randomised trials.

Sadeghirad B, Siemieniuk RAC, Brignardello-Petersen R, Papola D, Lytvyn L, Vandvik PO, Merglen A, Guyatt GH, Agoritsas T
BMJ 2017 Sep 20;358:j3887. doi: 10.1136/bmj.j3887. PMID: 28931508 Free PMC Article

Dysphagia after stroke: incidence, diagnosis, and pulmonary complications.

Martino R, Foley N, Bhogal S, Diamant N, Speechley M, Teasell R
Stroke 2005 Dec;36(12):2756-63. Epub 2005 Nov 3 doi: 10.1161/01.STR.0000190056.76543.eb. PMID: 16269630

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MedGen

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Disorder of pharynx

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

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