U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Small intestinal tubulovillous adenoma

MedGen UID:
354182
•Concept ID:
C1710113
•
Neoplastic Process
Synonyms: Small Intestinal Tubulovillous Adenoma; small intestinal tubulovillous adenoma
 
Monarch Initiative: MONDO:0006422

Definition

A neoplasm that arises from the glandular epithelium of the small intestine. It is characterized by tubular and villous architectural patterns. The neoplastic glandular cells have dysplastic features. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSmall intestinal tubulovillous adenoma

Recent clinical studies

Etiology

Multi-slice spiral CT findings of tubulovillous adenoma of the duodenum.
Li LC, Zheng LR, Han N
Clin Imaging 2022 Feb;82:135-138. Epub 2021 Nov 18 doi: 10.1016/j.clinimag.2021.11.015. PMID: 34813992
Safety and efficacy of cap-assisted EMR for sporadic nonampullary duodenal adenomas.
Jamil LH, Kashani A, Peter N, Lo SK
Gastrointest Endosc 2017 Oct;86(4):666-672. Epub 2017 Feb 28 doi: 10.1016/j.gie.2017.02.023. PMID: 28257791
Adenoma of the papilla and ampulla--premalignant lesions?
Wittekind C, Tannapfel A
Langenbecks Arch Surg 2001 Apr;386(3):172-5. doi: 10.1007/s004230100234. PMID: 11382317
Ampullectomy for adenoma of the papilla and ampulla of Vater.
Beger HG, Staib L, Schoenberg MH
Langenbecks Arch Surg 1998 Apr;383(2):190-3. doi: 10.1007/s004230050117. PMID: 9641898
Colorectal polyps and their relationship to cancer.
Kim EC, Lance P
Gastroenterol Clin North Am 1997 Mar;26(1):1-17. doi: 10.1016/s0889-8553(05)70280-6. PMID: 9119435

Diagnosis

Multi-slice spiral CT findings of tubulovillous adenoma of the duodenum.
Li LC, Zheng LR, Han N
Clin Imaging 2022 Feb;82:135-138. Epub 2021 Nov 18 doi: 10.1016/j.clinimag.2021.11.015. PMID: 34813992
Colonic Adenomatous Polyps Involving Submucosal Lymphoglandular Complexes: A Diagnostic Pitfall.
Lee HE, Wu TT, Chandan VS, Torbenson MS, Mounajjed T
Am J Surg Pathol 2018 Aug;42(8):1083-1089. doi: 10.1097/PAS.0000000000001081. PMID: 29738362
Surgical management of benign duodenal tumours.
Yan JQ, Peng CH, Yang WP, Ding JZ, Zhou GW, Ma D, Li HW
ANZ J Surg 2010 Jul-Aug;80(7-8):526-30. doi: 10.1111/j.1445-2197.2010.05378.x. PMID: 20795967
Small intestinal tubulovillous adenoma--case report and literature review.
Osifo OD, Akhiwu W, Efobi CA
Niger J Clin Pract 2009 Jun;12(2):205-7. PMID: 19764676
Colorectal polyps and their relationship to cancer.
Kim EC, Lance P
Gastroenterol Clin North Am 1997 Mar;26(1):1-17. doi: 10.1016/s0889-8553(05)70280-6. PMID: 9119435

Therapy

Ampullary Adenoma Treated by Endoscopic Double-Snare Retracting Papillectomy.
Soma H, Miyata N, Hozawa S, Higuchi H, Yamagishi Y, Nakamura Y, Saeki K, Kameyama K, Masugi Y, Yahagi N, Kanai T
Gut Liver 2015 Sep 23;9(5):689-92. doi: 10.5009/gnl14206. PMID: 26087781Free PMC Article
Adenomas of the ampulla of Vater: a comparison of outcomes of operative and endoscopic resections.
Onkendi EO, Naik ND, Rosedahl JK, Harmsen SW, Gostout CJ, Baron TH Sr, Sarr MG, Que FG
J Gastrointest Surg 2014 Sep;18(9):1588-96. Epub 2014 Jun 11 doi: 10.1007/s11605-014-2543-z. PMID: 24916584
"Underwater" EMR of sporadic laterally spreading nonampullary duodenal adenomas (with video).
Binmoeller KF, Shah JN, Bhat YM, Kane SD
Gastrointest Endosc 2013 Sep;78(3):496-502. Epub 2013 May 2 doi: 10.1016/j.gie.2013.03.1330. PMID: 23642790
Double balloon enteroscopy in children: diagnosis, treatment, and safety.
Thomson M, Venkatesh K, Elmalik K, van der Veer W, Jaacobs M
World J Gastroenterol 2010 Jan 7;16(1):56-62. doi: 10.3748/wjg.v16.i1.56. PMID: 20039449Free PMC Article
Outcome of laparoscopic colectomy for polyps not suitable for endoscopic resection.
Pokala N, Delaney CP, Kiran RP, Brady K, Senagore AJ
Surg Endosc 2007 Mar;21(3):400-3. Epub 2006 Dec 16 doi: 10.1007/s00464-006-9069-8. PMID: 17180271

Prognosis

Multi-slice spiral CT findings of tubulovillous adenoma of the duodenum.
Li LC, Zheng LR, Han N
Clin Imaging 2022 Feb;82:135-138. Epub 2021 Nov 18 doi: 10.1016/j.clinimag.2021.11.015. PMID: 34813992
Colonic Adenomatous Polyps Involving Submucosal Lymphoglandular Complexes: A Diagnostic Pitfall.
Lee HE, Wu TT, Chandan VS, Torbenson MS, Mounajjed T
Am J Surg Pathol 2018 Aug;42(8):1083-1089. doi: 10.1097/PAS.0000000000001081. PMID: 29738362
Surgical management of benign duodenal tumours.
Yan JQ, Peng CH, Yang WP, Ding JZ, Zhou GW, Ma D, Li HW
ANZ J Surg 2010 Jul-Aug;80(7-8):526-30. doi: 10.1111/j.1445-2197.2010.05378.x. PMID: 20795967
Clinical significance of small colorectal adenoma less than 10 mm: the KASID study.
Yoo TW, Park DI, Kim YH, Kim HS, Kim WH, Kim TI, Kim HJ, Yang SK, Byeon JS, Lee MS, Jung IK, Chung MK, Jung SA, Jeen YT, Choi JH, Choi H, Han DS, Song JS
Hepatogastroenterology 2007 Mar;54(74):418-21. PMID: 17523287
Ampullectomy for adenoma of the papilla and ampulla of Vater.
Beger HG, Staib L, Schoenberg MH
Langenbecks Arch Surg 1998 Apr;383(2):190-3. doi: 10.1007/s004230050117. PMID: 9641898

Clinical prediction guides

Endocytoscopic observation with methylene blue staining for duodenal neoplasms associated with familial adenomatous polyposis.
Kumagai Y, Yamamoto E, Higashi M, Ishiguro T, Hatano S, Toyomasu Y, Amano K, Suzuki O, Ishibashi KI, Mochiki E, Tamaru JI, Ishida H
Sci Rep 2020 Nov 5;10(1):19221. doi: 10.1038/s41598-020-76309-6. PMID: 33154543Free PMC Article
Colonic Adenomatous Polyps Involving Submucosal Lymphoglandular Complexes: A Diagnostic Pitfall.
Lee HE, Wu TT, Chandan VS, Torbenson MS, Mounajjed T
Am J Surg Pathol 2018 Aug;42(8):1083-1089. doi: 10.1097/PAS.0000000000001081. PMID: 29738362
Human intestinal spirochetosis: right-side preference in the large intestine.
Ogata S, Shimizu K, Nakanishi K
Ann Diagn Pathol 2015 Dec;19(6):414-7. Epub 2015 Oct 21 doi: 10.1016/j.anndiagpath.2015.10.004. PMID: 26597024
Ampullary Adenoma Treated by Endoscopic Double-Snare Retracting Papillectomy.
Soma H, Miyata N, Hozawa S, Higuchi H, Yamagishi Y, Nakamura Y, Saeki K, Kameyama K, Masugi Y, Yahagi N, Kanai T
Gut Liver 2015 Sep 23;9(5):689-92. doi: 10.5009/gnl14206. PMID: 26087781Free PMC Article
Clinical significance of small colorectal adenoma less than 10 mm: the KASID study.
Yoo TW, Park DI, Kim YH, Kim HS, Kim WH, Kim TI, Kim HJ, Yang SK, Byeon JS, Lee MS, Jung IK, Chung MK, Jung SA, Jeen YT, Choi JH, Choi H, Han DS, Song JS
Hepatogastroenterology 2007 Mar;54(74):418-21. PMID: 17523287

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...