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Thymic Atypical Carcinoid Tumor

MedGen UID:
354249
Concept ID:
C1710396
Neoplastic Process

Definition

A primary thymic carcinoid tumor, characterized by a high mitotic rate often associated with the presence of necrosis and nuclear pleomorphism. This type of thymic carcinoid tumor has a more aggressive clinical course, compared to typical thymic carcinoid tumors. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVThymic Atypical Carcinoid Tumor

Professional guidelines

PubMed

Mlika M, Boudaya S, Braham E, Chermiti F, Sayi A, Marghli A, El Mezni F
Asian Cardiovasc Thorac Ann 2016 May;24(4):350-4. Epub 2016 Mar 21 doi: 10.1177/0218492316640129. PMID: 27002097
Vadász P, Kotsis L, Egerváry M, Pálffy G
Thorac Cardiovasc Surg 1999 Aug;47(4):235-9. doi: 10.1055/s-2007-1013150. PMID: 10522793

Recent clinical studies

Etiology

Koehler K, Iams WT
Cancer Med 2023 Apr;12(7):7893-7903. Epub 2022 Dec 22 doi: 10.1002/cam4.5564. PMID: 36560885Free PMC Article
Kashima J, Hashimoto T, Yoshida A, Goto Y, Ushiku T, Ohe Y, Watanabe SI, Yatabe Y
Virchows Arch 2022 Dec;481(6):893-901. Epub 2022 Oct 28 doi: 10.1007/s00428-022-03437-x. PMID: 36305944
Hou T, Gan Q, Joseph CT, Sun X, Gong Y
Cancer Cytopathol 2020 Oct;128(10):725-732. Epub 2020 Jun 23 doi: 10.1002/cncy.22310. PMID: 32573984
Wang X, Li Y, Duan J, Chen Y, Yuan B, Qi Z, Tan H
Oncologist 2019 Jun;24(6):798-802. Epub 2018 Nov 9 doi: 10.1634/theoncologist.2018-0291. PMID: 30413666Free PMC Article
Litvak A, Pietanza MC
Hematol Oncol Clin North Am 2016 Feb;30(1):83-102. doi: 10.1016/j.hoc.2015.09.003. PMID: 26614370

Diagnosis

Koehler K, Iams WT
Cancer Med 2023 Apr;12(7):7893-7903. Epub 2022 Dec 22 doi: 10.1002/cam4.5564. PMID: 36560885Free PMC Article
Kashima J, Hashimoto T, Yoshida A, Goto Y, Ushiku T, Ohe Y, Watanabe SI, Yatabe Y
Virchows Arch 2022 Dec;481(6):893-901. Epub 2022 Oct 28 doi: 10.1007/s00428-022-03437-x. PMID: 36305944
Lang M, Hackert T, Anamaterou C
Clin Endocrinol (Oxf) 2021 Nov;95(5):744-751. Epub 2021 Aug 26 doi: 10.1111/cen.14572. PMID: 34323309
Park SY, Han KN, Hong JI, Kim HK, Kim DJ, Choi YH
Eur J Cardiothorac Surg 2020 Aug 1;58(Suppl_1):i34-i38. doi: 10.1093/ejcts/ezaa036. PMID: 32061087
Litvak A, Pietanza MC
Hematol Oncol Clin North Am 2016 Feb;30(1):83-102. doi: 10.1016/j.hoc.2015.09.003. PMID: 26614370

Therapy

Lang M, Hackert T, Anamaterou C
Clin Endocrinol (Oxf) 2021 Nov;95(5):744-751. Epub 2021 Aug 26 doi: 10.1111/cen.14572. PMID: 34323309
Park SY, Han KN, Hong JI, Kim HK, Kim DJ, Choi YH
Eur J Cardiothorac Surg 2020 Aug 1;58(Suppl_1):i34-i38. doi: 10.1093/ejcts/ezaa036. PMID: 32061087
Wang X, Li Y, Duan J, Chen Y, Yuan B, Qi Z, Tan H
Oncologist 2019 Jun;24(6):798-802. Epub 2018 Nov 9 doi: 10.1634/theoncologist.2018-0291. PMID: 30413666Free PMC Article
Mei Z, Wang H, Ren S, Wei J, Gu Y
Medicine (Baltimore) 2018 Nov;97(47):e13286. doi: 10.1097/MD.0000000000013286. PMID: 30461637Free PMC Article
Litvak A, Pietanza MC
Hematol Oncol Clin North Am 2016 Feb;30(1):83-102. doi: 10.1016/j.hoc.2015.09.003. PMID: 26614370

Prognosis

Koehler K, Iams WT
Cancer Med 2023 Apr;12(7):7893-7903. Epub 2022 Dec 22 doi: 10.1002/cam4.5564. PMID: 36560885Free PMC Article
Dinter H, Bohnenberger H, Beck J, Bornemann-Kolatzki K, Schütz E, Küffer S, Klein L, Franks TJ, Roden A, Emmert A, Hinterthaner M, Marino M, Brcic L, Popper H, Weis CA, Pelosi G, Marx A, Ströbel P
J Thorac Oncol 2019 Aug;14(8):1472-1483. Epub 2019 Apr 28 doi: 10.1016/j.jtho.2019.04.015. PMID: 31042566
Mlika M, Boudaya S, Braham E, Chermiti F, Sayi A, Marghli A, El Mezni F
Asian Cardiovasc Thorac Ann 2016 May;24(4):350-4. Epub 2016 Mar 21 doi: 10.1177/0218492316640129. PMID: 27002097
Litvak A, Pietanza MC
Hematol Oncol Clin North Am 2016 Feb;30(1):83-102. doi: 10.1016/j.hoc.2015.09.003. PMID: 26614370
Hosaka Y, Tsuchida M, Toyabe S, Umezu H, Eimoto T, Hayashi J
Ann Thorac Surg 2010 Mar;89(3):912-7. doi: 10.1016/j.athoracsur.2009.11.057. PMID: 20172153

Clinical prediction guides

Lang M, Hackert T, Anamaterou C
Clin Endocrinol (Oxf) 2021 Nov;95(5):744-751. Epub 2021 Aug 26 doi: 10.1111/cen.14572. PMID: 34323309
Remes SM, Leijon H, Vesterinen T, Louhimo J, Pulkkinen V, Ezer S, Kere J, Haglund C, Arola J
APMIS 2020 Nov;128(11):563-572. Epub 2020 Sep 28 doi: 10.1111/apm.13071. PMID: 32794589Free PMC Article
Dinter H, Bohnenberger H, Beck J, Bornemann-Kolatzki K, Schütz E, Küffer S, Klein L, Franks TJ, Roden A, Emmert A, Hinterthaner M, Marino M, Brcic L, Popper H, Weis CA, Pelosi G, Marx A, Ströbel P
J Thorac Oncol 2019 Aug;14(8):1472-1483. Epub 2019 Apr 28 doi: 10.1016/j.jtho.2019.04.015. PMID: 31042566
Mlika M, Boudaya S, Braham E, Chermiti F, Sayi A, Marghli A, El Mezni F
Asian Cardiovasc Thorac Ann 2016 May;24(4):350-4. Epub 2016 Mar 21 doi: 10.1177/0218492316640129. PMID: 27002097
Hosaka Y, Tsuchida M, Toyabe S, Umezu H, Eimoto T, Hayashi J
Ann Thorac Surg 2010 Mar;89(3):912-7. doi: 10.1016/j.athoracsur.2009.11.057. PMID: 20172153

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