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Clear cell papillary cystadenoma

MedGen UID:
361270
•Concept ID:
C1880102
•
Neoplastic Process
Synonyms: Clear Cell Papillary Cystadenoma; clear cell papillary cystadenoma
 
Monarch Initiative: MONDO:0006149

Definition

A benign cystic glandular epithelial neoplasm characterized by the presence of neoplastic clear or hobnail cells which form papillary structures. There is no evidence of stromal invasion. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVClear cell papillary cystadenoma

Professional guidelines

PubMed

Usefulness of PET/CT 18-FDG for the diagnosis and follow-up of urological, urothelial and kidney tumours.
González-Ruiz de León C, García-Rodríguez J, Pérez-Castro N, Vigil-Díaz C, Pérez-Haro ML, Fernández-Gómez JM
Actas Urol Esp (Engl Ed) 2019 Jan-Feb;43(1):32-38. Epub 2018 Aug 9 doi: 10.1016/j.acuro.2018.05.005. PMID: 30100141

Recent clinical studies

Etiology

Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Garg K, Karnezis AN, Rabban JT
Pathology 2018 Feb;50(2):238-256. Epub 2018 Jan 17 doi: 10.1016/j.pathol.2017.10.009. PMID: 29373116

Diagnosis

Clear Cell Papillary Cystadenoma of the Ovary Masquerading as Metastatic Clear Cell Renal Cell Carcinoma: A Case Report and Review of the Literature.
Sharma AE, Hamedani FS, Barroeta JE, Pytel P, Bennett JA, Lastra RR
Int J Gynecol Pathol 2021 May 1;40(3):290-295. doi: 10.1097/PGP.0000000000000666. PMID: 31985579
Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Garg K, Karnezis AN, Rabban JT
Pathology 2018 Feb;50(2):238-256. Epub 2018 Jan 17 doi: 10.1016/j.pathol.2017.10.009. PMID: 29373116
The utility of PAX-2 in distinguishing metastatic clear cell renal cell carcinoma from its morphologic mimics: an immunohistochemical study with comparison to renal cell carcinoma marker.
Gokden N, Gokden M, Phan DC, McKenney JK
Am J Surg Pathol 2008 Oct;32(10):1462-7. doi: 10.1097/PAS.0b013e318176dba7. PMID: 18685487
Clear cell papillary cystadenoma of epididymis, a mimic of metastatic renal cell carcinoma.
Yaqoob N, Ahsan A, Ahmad Z, Khan AN
J Pak Med Assoc 2008 Apr;58(4):209-11. PMID: 18655434
Clear cell papillary cystadenoma of the epididymis and mesosalpinx: immunohistochemical differentiation from metastatic clear cell renal cell carcinoma.
Aydin H, Young RH, Ronnett BM, Epstein JI
Am J Surg Pathol 2005 Apr;29(4):520-3. doi: 10.1097/01.pas.0000155160.36154.ml. PMID: 15767808

Prognosis

Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Garg K, Karnezis AN, Rabban JT
Pathology 2018 Feb;50(2):238-256. Epub 2018 Jan 17 doi: 10.1016/j.pathol.2017.10.009. PMID: 29373116
The utility of PAX-2 in distinguishing metastatic clear cell renal cell carcinoma from its morphologic mimics: an immunohistochemical study with comparison to renal cell carcinoma marker.
Gokden N, Gokden M, Phan DC, McKenney JK
Am J Surg Pathol 2008 Oct;32(10):1462-7. doi: 10.1097/PAS.0b013e318176dba7. PMID: 18685487

Clinical prediction guides

Uncommon hereditary gynaecological tumour syndromes: pathological features in tumours that may predict risk for a germline mutation.
Garg K, Karnezis AN, Rabban JT
Pathology 2018 Feb;50(2):238-256. Epub 2018 Jan 17 doi: 10.1016/j.pathol.2017.10.009. PMID: 29373116
The utility of PAX-2 in distinguishing metastatic clear cell renal cell carcinoma from its morphologic mimics: an immunohistochemical study with comparison to renal cell carcinoma marker.
Gokden N, Gokden M, Phan DC, McKenney JK
Am J Surg Pathol 2008 Oct;32(10):1462-7. doi: 10.1097/PAS.0b013e318176dba7. PMID: 18685487

Supplemental Content

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