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Dissociative disorder

MedGen UID:
3871
•Concept ID:
C0012746
•
Mental or Behavioral Dysfunction
Synonyms: Disorder, Dissociative; Disorders, Dissociative; Dissociative Disorder; Dissociative Disorders; Dissociative Reaction; Dissociative Reactions; Reaction, Dissociative; Reactions, Dissociative
SNOMED CT: Dissociative disorder (44376007)
 
HPO: HP:0032940
Monarch Initiative: MONDO:0001160

Definition

Disruption or detachment of certain aspects of one's normal psychological functioning typically involves a disconnection or separation from thoughts, feelings, sensations, memories, or one's sense of identity or reality. [from HPO]

Professional guidelines

PubMed

Barriers to accessing and continuing mental health treatment among individuals with dissociative symptoms.
Nester MS, Hawkins SL, Brand BL
Eur J Psychotraumatol 2022;13(1):2031594. Epub 2022 Feb 17 doi: 10.1080/20008198.2022.2031594. PMID: 35186217Free PMC Article
Dissociative identity disorder and schizophrenia: differential diagnosis and theoretical issues.
Foote B, Park J
Curr Psychiatry Rep 2008 Jun;10(3):217-22. doi: 10.1007/s11920-008-0036-z. PMID: 18652789
The differential diagnosis of epilepsy, pseudoseizures, dissociative identity disorder, and dissociative disorder not otherwise specified.
Bowman ES, Coons PM
Bull Menninger Clin 2000 Spring;64(2):164-80. PMID: 10842446

Recent clinical studies

Etiology

The Molecular Genetics of Dissociative Symptomatology: A Transdiagnostic Literature Review.
Rajkumar RP
Genes (Basel) 2022 May 8;13(5) doi: 10.3390/genes13050843. PMID: 35627228Free PMC Article
Low high-density lipoprotein and psychopathology: A review.
Douglas J, Nasrallah HA
Ann Clin Psychiatry 2019 Aug;31(3):209-213. PMID: 31369659
Fibromyalgia and dissociative symptoms.
Duarte JM, Crow C, Antik A, Appiani F, Caride A
CNS Spectr 2019 Dec;24(6):605-608. doi: 10.1017/S1092852918001608. PMID: 30894235
Dissociation debates: everything you know is wrong.
Loewenstein RJ
Dialogues Clin Neurosci 2018 Sep;20(3):229-242. doi: 10.31887/DCNS.2018.20.3/rloewenstein. PMID: 30581293Free PMC Article
Dissociative disorders in DSM-5.
Spiegel D, Loewenstein RJ, Lewis-Fernández R, Sar V, Simeon D, Vermetten E, Cardeña E, Dell PF
Depress Anxiety 2011 Sep;28(9):824-52. doi: 10.1002/da.20874. PMID: 21910187

Diagnosis

Sleep-Related Dissociative Disorders.
Eiser AS
Sleep Med Clin 2024 Mar;19(1):159-167. Epub 2023 Nov 22 doi: 10.1016/j.jsmc.2023.10.003. PMID: 38368062
The Molecular Genetics of Dissociative Symptomatology: A Transdiagnostic Literature Review.
Rajkumar RP
Genes (Basel) 2022 May 8;13(5) doi: 10.3390/genes13050843. PMID: 35627228Free PMC Article
The Dissociative Taxon and Dissociative Identity Disorder.
Ross CA
J Trauma Dissociation 2021 Oct-Dec;22(5):555-562. Epub 2021 Jan 31 doi: 10.1080/15299732.2020.1869645. PMID: 33522454
Dissociative disorders.
Kihlstrom JF
Annu Rev Clin Psychol 2005;1:227-53. doi: 10.1146/annurev.clinpsy.1.102803.143925. PMID: 17716088
Pseudoseizures.
Bowman ES
Psychiatr Clin North Am 1998 Sep;21(3):649-57, vii. doi: 10.1016/s0193-953x(05)70029-0. PMID: 9774802

Therapy

Trauma and dissociation among inpatients diagnosed with schizophrenia spectrum disorders in Taiwan.
Wu ZY, Fung HW, Chien WT, Ross CA, Lam SKK
Eur J Psychotraumatol 2022;13(2):2105576. Epub 2022 Aug 11 doi: 10.1080/20008066.2022.2105576. PMID: 35979506Free PMC Article
Reconsidering the autohypnotic model of the dissociative disorders.
Dell PF
J Trauma Dissociation 2019 Jan-Feb;20(1):48-78. Epub 2018 Mar 22 doi: 10.1080/15299732.2018.1451806. PMID: 29565750
Abreaction for conversion disorder: systematic review with meta-analysis.
Poole NA, Wuerz A, Agrawal N
Br J Psychiatry 2010 Aug;197(2):91-5. doi: 10.1192/bjp.bp.109.066894. PMID: 20679259
A review of dissociative disorders treatment studies.
Brand BL, Classen CC, McNary SW, Zaveri P
J Nerv Ment Dis 2009 Sep;197(9):646-54. doi: 10.1097/NMD.0b013e3181b3afaa. PMID: 19752643
Pseudoseizures: an overview.
Volow MR
South Med J 1986 May;79(5):600-7. doi: 10.1097/00007611-198605000-00020. PMID: 3518074

Prognosis

Characteristics, Methods, And Functions Of Non-Suicidal Self-Injury Among Highly Dissociative Individuals.
Nester MS, Pierorazio NA, Shandler G, Brand BL
J Trauma Dissociation 2023 May-Jun;24(3):333-347. Epub 2023 Feb 20 doi: 10.1080/15299732.2023.2181475. PMID: 36803534
Ganser syndrome - a dissociative disorder or a factitious disorder? A case report.
Wincewicz K, Sapota-Zaręba K, Nasierowski T
Psychiatr Pol 2022 Feb 27;56(1):63-75. doi: 10.12740/PP/129012. PMID: 35569148
A systematic scoping review of dissociation in borderline personality disorder and implications for research and clinical practice: Exploring the fog.
Al-Shamali HF, Winkler O, Talarico F, Greenshaw AJ, Forner C, Zhang Y, Vermetten E, Burback L
Aust N Z J Psychiatry 2022 Oct;56(10):1252-1264. Epub 2022 Feb 13 doi: 10.1177/00048674221077029. PMID: 35152771Free PMC Article
Dissociative sensibility disorders - A retrospective case series and systematic literature review.
Weber P, Erlacher R
Eur J Paediatr Neurol 2018 Jan;22(1):27-38. Epub 2017 Sep 1 doi: 10.1016/j.ejpn.2017.08.005. PMID: 28899586
Abreaction for conversion disorder: systematic review with meta-analysis.
Poole NA, Wuerz A, Agrawal N
Br J Psychiatry 2010 Aug;197(2):91-5. doi: 10.1192/bjp.bp.109.066894. PMID: 20679259

Clinical prediction guides

Stress response in dissociation and conversion disorders: A systematic review.
Boulet C, Lopez-Castroman J, Mouchabac S, Olié E, Courtet P, Thouvenot E, Abbar M, Conejero I
Neurosci Biobehav Rev 2022 Jan;132:957-967. Epub 2021 Nov 2 doi: 10.1016/j.neubiorev.2021.10.049. PMID: 34740754
Hystero-epilepsy in the Tuesday Lessons and NMDA receptor function: A hypothesis for dissociative disorder.
Komagamine T, Kokubun N, Hirata K
Med Hypotheses 2021 May;150:110567. Epub 2021 Mar 23 doi: 10.1016/j.mehy.2021.110567. PMID: 33799161
Fibromyalgia and dissociative symptoms.
Duarte JM, Crow C, Antik A, Appiani F, Caride A
CNS Spectr 2019 Dec;24(6):605-608. doi: 10.1017/S1092852918001608. PMID: 30894235
An outpatient clinical study of dissociative disorder not otherwise specified.
Yanartaş Ö, Özmen HA, Citak S, Zincir SB, Sünbül EA
Compr Psychiatry 2014 May;55(4):755-61. Epub 2013 Dec 23 doi: 10.1016/j.comppsych.2013.12.015. PMID: 24461163
Pseudoseizures: an overview.
Volow MR
South Med J 1986 May;79(5):600-7. doi: 10.1097/00007611-198605000-00020. PMID: 3518074

Recent systematic reviews

A systematic scoping review of dissociation in borderline personality disorder and implications for research and clinical practice: Exploring the fog.
Al-Shamali HF, Winkler O, Talarico F, Greenshaw AJ, Forner C, Zhang Y, Vermetten E, Burback L
Aust N Z J Psychiatry 2022 Oct;56(10):1252-1264. Epub 2022 Feb 13 doi: 10.1177/00048674221077029. PMID: 35152771Free PMC Article
Stress response in dissociation and conversion disorders: A systematic review.
Boulet C, Lopez-Castroman J, Mouchabac S, Olié E, Courtet P, Thouvenot E, Abbar M, Conejero I
Neurosci Biobehav Rev 2022 Jan;132:957-967. Epub 2021 Nov 2 doi: 10.1016/j.neubiorev.2021.10.049. PMID: 34740754
Pharmacotherapy for dissociative disorders: A systematic review.
Sutar R, Sahu S
Psychiatry Res 2019 Nov;281:112529. Epub 2019 Aug 23 doi: 10.1016/j.psychres.2019.112529. PMID: 31470213
Dissociative sensibility disorders - A retrospective case series and systematic literature review.
Weber P, Erlacher R
Eur J Paediatr Neurol 2018 Jan;22(1):27-38. Epub 2017 Sep 1 doi: 10.1016/j.ejpn.2017.08.005. PMID: 28899586
Conversion disorder: A systematic review of current terminology.
Ding JM, Kanaan RA
Gen Hosp Psychiatry 2017 Mar-Apr;45:51-55. Epub 2016 Dec 24 doi: 10.1016/j.genhosppsych.2016.12.009. PMID: 28274339

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