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Genital warts

MedGen UID:
40445
Concept ID:
C0009663
Disease or Syndrome
Synonyms: Condylomata Acuminata; Genital Wart; Genital Warts; Venereal Wart; Venereal Warts; Wart, Genital; Wart, Venereal; Warts, Genital; Warts, Venereal
SNOMED CT: Venereal wart (240542006); Venereal warts (240542006); Anogenital warts (240542006); Anogenital wart (240542006); AGW - Anogenital warts (240542006); Verruca acuminata (240542006); Condyloma acuminatum of the anogenital region (240542006); Condylomata acuminatum of the anogenital region (240542006); Genital warts (266113007); Genital wart (266113007)
 
HPO: HP:0032301

Definition

Warts affecting the skin in the genital area (penile shaft, scrotum, vagina, or labia majora). Warts can be small, beginning as a pinhead-size swelling that may become larger and take on a pedunculated appearance. Warts can spread and coalesce into large masses in the genital or anal area. Their color is variable but tends to be skin colored or darker, and they may occasionally bleed. Warts may cause itching, redness, or discomfort. An outbreak of genital warts may also cause psychological distress. [from HPO]

Professional guidelines

PubMed

Ntanasis-Stathopoulos I, Kyriazoglou A, Liontos M, A Dimopoulos M, Gavriatopoulou M
J BUON 2020 May-Jun;25(3):1281-1285. PMID: 32862567
Yuan J, Ni G, Wang T, Mounsey K, Cavezza S, Pan X, Liu X
Hum Vaccin Immunother 2018 Jul 3;14(7):1815-1819. Epub 2018 Apr 9 doi: 10.1080/21645515.2018.1445947. PMID: 29505317Free PMC Article
Workowski KA, Bolan GA; Centers for Disease Control and Prevention
MMWR Recomm Rep 2015 Jun 5;64(RR-03):1-137. PMID: 26042815Free PMC Article

Recent clinical studies

Etiology

Oyouni AAA
J Infect Public Health 2023 Apr;16(4):626-631. Epub 2023 Feb 21 doi: 10.1016/j.jiph.2023.02.014. PMID: 36868166
Yuan J, Ni G, Wang T, Mounsey K, Cavezza S, Pan X, Liu X
Hum Vaccin Immunother 2018 Jul 3;14(7):1815-1819. Epub 2018 Apr 9 doi: 10.1080/21645515.2018.1445947. PMID: 29505317Free PMC Article
Steben M, Garland SM
Best Pract Res Clin Obstet Gynaecol 2014 Oct;28(7):1063-73. Epub 2014 Jul 17 doi: 10.1016/j.bpobgyn.2014.07.002. PMID: 25155525
Markle W, Conti T, Kad M
Prim Care 2013 Sep;40(3):557-87. Epub 2013 Jun 29 doi: 10.1016/j.pop.2013.05.001. PMID: 23958358
Dupin N
Clin Dermatol 2004 Nov-Dec;22(6):481-6. doi: 10.1016/j.clindermatol.2004.07.003. PMID: 15596319

Diagnosis

Med Lett Drugs Ther 2022 Jun 27;64(1653):97-104. PMID: 35750325
Steben M, Garland SM
Best Pract Res Clin Obstet Gynaecol 2014 Oct;28(7):1063-73. Epub 2014 Jul 17 doi: 10.1016/j.bpobgyn.2014.07.002. PMID: 25155525
Markle W, Conti T, Kad M
Prim Care 2013 Sep;40(3):557-87. Epub 2013 Jun 29 doi: 10.1016/j.pop.2013.05.001. PMID: 23958358
Wiley DJ
Clin Evid 2002 Jun;(7):1426-36. PMID: 12230758
Prasad CJ
Clin Lab Med 1995 Sep;15(3):685-704. PMID: 8542729

Therapy

Med Lett Drugs Ther 2022 Jun 27;64(1653):97-104. PMID: 35750325
Med Lett Drugs Ther 2018 May 7;60(1546):73-82. PMID: 29746447
Steben M, Garland SM
Best Pract Res Clin Obstet Gynaecol 2014 Oct;28(7):1063-73. Epub 2014 Jul 17 doi: 10.1016/j.bpobgyn.2014.07.002. PMID: 25155525
Markle W, Conti T, Kad M
Prim Care 2013 Sep;40(3):557-87. Epub 2013 Jun 29 doi: 10.1016/j.pop.2013.05.001. PMID: 23958358
Wiley DJ
Clin Evid 2002 Jun;(7):1426-36. PMID: 12230758

Prognosis

Stratton KL, Culkin DJ
Oncology (Williston Park) 2016 Mar;30(3):245-9. PMID: 26984219
Alhamlan FS, Al-Qahtani AA, Al-Ahdal MN
J Infect Dev Ctries 2015 Jul 4;9(6):571-6. doi: 10.3855/jidc.6538. PMID: 26142665
Markle W, Conti T, Kad M
Prim Care 2013 Sep;40(3):557-87. Epub 2013 Jun 29 doi: 10.1016/j.pop.2013.05.001. PMID: 23958358
Schneider C, Segre T
Am Fam Physician 2009 Apr 1;79(7):591-4. PMID: 19378876
Simmons PD
Int J Dermatol 1983 Sep;22(7):410-4. doi: 10.1111/j.1365-4362.1983.tb02159.x. PMID: 6629603

Clinical prediction guides

Kechagias KS, Kalliala I, Bowden SJ, Athanasiou A, Paraskevaidi M, Paraskevaidis E, Dillner J, Nieminen P, Strander B, Sasieni P, Veroniki AA, Kyrgiou M
BMJ 2022 Aug 3;378:e070135. doi: 10.1136/bmj-2022-070135. PMID: 35922074Free PMC Article
Ntanasis-Stathopoulos I, Kyriazoglou A, Liontos M, A Dimopoulos M, Gavriatopoulou M
J BUON 2020 May-Jun;25(3):1281-1285. PMID: 32862567
Ferris D, Samakoses R, Block SL, Lazcano-Ponce E, Restrepo JA, Reisinger KS, Mehlsen J, Chatterjee A, Iversen OE, Sings HL, Shou Q, Sausser TA, Saah A
Pediatrics 2014 Sep;134(3):e657-65. Epub 2014 Aug 18 doi: 10.1542/peds.2013-4144. PMID: 25136050
Stanley M
Gynecol Oncol 2010 May;117(2 Suppl):S5-10. doi: 10.1016/j.ygyno.2010.01.024. PMID: 20304221
Markowitz LE, Hariri S, Unger ER, Saraiya M, Datta SD, Dunne EF
Vaccine 2010 Jul 5;28(30):4731-7. Epub 2010 Feb 25 doi: 10.1016/j.vaccine.2010.02.019. PMID: 20188681

Recent systematic reviews

Kechagias KS, Kalliala I, Bowden SJ, Athanasiou A, Paraskevaidi M, Paraskevaidis E, Dillner J, Nieminen P, Strander B, Sasieni P, Veroniki AA, Kyrgiou M
BMJ 2022 Aug 3;378:e070135. doi: 10.1136/bmj-2022-070135. PMID: 35922074Free PMC Article
Kwok CS, Gibbs S, Bennett C, Holland R, Abbott R
Cochrane Database Syst Rev 2012 Sep 12;2012(9):CD001781. doi: 10.1002/14651858.CD001781.pub3. PMID: 22972052Free PMC Article
W Buck H Jr
BMJ Clin Evid 2010 Aug 13;2010 PMID: 21418685Free PMC Article
W Buck H Jr
BMJ Clin Evid 2007 Aug 1;2007 PMID: 19454104Free PMC Article
Burstein GR, Workowski KA
Curr Opin Pediatr 2003 Aug;15(4):391-7. doi: 10.1097/00008480-200308000-00006. PMID: 12891051

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