U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Dyskinesia of esophagus

MedGen UID:
41868
Concept ID:
C0014858
Disease or Syndrome
Synonyms: Disorder, Esophageal Motility; Disorders, Esophageal Motility; Dysmotilities, Esophageal; Dysmotility, Esophageal; Esophageal Dysmotilities; Esophageal Dysmotility; Esophageal Motility Disorder; Esophageal Motility Disorders; Motility Disorder, Esophageal; Motility Disorders, Esophageal
SNOMED CT: Esophageal dysmotility (266434009); Dyskinesia of esophagus (79962008); Esophageal motility disorder (79962008); Esophageal motor disorder (79962008)
 
Monarch Initiative: MONDO:0004729

Definition

Disorders affecting the motor function of the upper esophageal sphincter; lower esophageal sphincter; the esophagus body, or a combination of these parts. The failure of the sphincters to maintain a tonic pressure may result in gastric reflux of food and acid into the esophagus (gastroesophageal reflux). Other disorders include hypermotility (spastic disorders) and markedly increased amplitude in contraction (nutcracker esophagus). [from MONDO]

Professional guidelines

PubMed

Yadlapati R, Gyawali CP, Pandolfino JE; CGIT GERD Consensus Conference Participants
Clin Gastroenterol Hepatol 2022 May;20(5):984-994.e1. Epub 2022 Feb 2 doi: 10.1016/j.cgh.2022.01.025. PMID: 35123084Free PMC Article
Katz PO, Dunbar KB, Schnoll-Sussman FH, Greer KB, Yadlapati R, Spechler SJ
Am J Gastroenterol 2022 Jan 1;117(1):27-56. doi: 10.14309/ajg.0000000000001538. PMID: 34807007Free PMC Article
Chen J, Brady P
Gastroenterol Nurs 2019 Jan/Feb;42(1):20-28. doi: 10.1097/SGA.0000000000000359. PMID: 30688703

Recent clinical studies

Etiology

Lin J, Liu G, Duan Z
Expert Rev Gastroenterol Hepatol 2021 Aug;15(8):919-927. Epub 2021 Jul 1 doi: 10.1080/17474124.2021.1945921. PMID: 34156876
Laliberte AS, Louie BE, Wilshire CL, Farivar AS, Bograd AJ, Aye RW
Surg Endosc 2021 Aug;35(8):4811-4816. Epub 2020 Aug 13 doi: 10.1007/s00464-020-07883-z. PMID: 32794047
Savarino E, Marabotto E, Savarino V
Curr Opin Gastroenterol 2018 Jul;34(4):243-248. doi: 10.1097/MOG.0000000000000439. PMID: 29846257
Kahrilas PJ, Bredenoord AJ, Fox M, Gyawali CP, Roman S, Smout AJ, Pandolfino JE; International High Resolution Manometry Working Group
Neurogastroenterol Motil 2015 Feb;27(2):160-74. Epub 2014 Dec 3 doi: 10.1111/nmo.12477. PMID: 25469569Free PMC Article
Thomas ML, Anthony AA, Fosh BG, Finch JG, Maddern GJ
Br J Surg 2001 May;88(5):629-42. doi: 10.1046/j.1365-2168.2001.01733.x. PMID: 11350433

Diagnosis

Patel DA, Yadlapati R, Vaezi MF
Gastroenterology 2022 May;162(6):1617-1634. Epub 2022 Feb 25 doi: 10.1053/j.gastro.2021.12.289. PMID: 35227779Free PMC Article
Fox MR, Sweis R, Yadlapati R, Pandolfino J, Hani A, Defilippi C, Jan T, Rommel N
Neurogastroenterol Motil 2021 Apr;33(4):e14120. Epub 2021 Mar 17 doi: 10.1111/nmo.14120. PMID: 33729668Free PMC Article
Yadlapati R, Kahrilas PJ, Fox MR, Bredenoord AJ, Prakash Gyawali C, Roman S, Babaei A, Mittal RK, Rommel N, Savarino E, Sifrim D, Smout A, Vaezi MF, Zerbib F, Akiyama J, Bhatia S, Bor S, Carlson DA, Chen JW, Cisternas D, Cock C, Coss-Adame E, de Bortoli N, Defilippi C, Fass R, Ghoshal UC, Gonlachanvit S, Hani A, Hebbard GS, Wook Jung K, Katz P, Katzka DA, Khan A, Kohn GP, Lazarescu A, Lengliner J, Mittal SK, Omari T, Park MI, Penagini R, Pohl D, Richter JE, Serra J, Sweis R, Tack J, Tatum RP, Tutuian R, Vela MF, Wong RK, Wu JC, Xiao Y, Pandolfino JE
Neurogastroenterol Motil 2021 Jan;33(1):e14058. doi: 10.1111/nmo.14058. PMID: 33373111Free PMC Article
Wilkinson JM, Halland M
Am Fam Physician 2020 Sep 1;102(5):291-296. PMID: 32866357
Triggs J, Pandolfino J
F1000Res 2019;8 Epub 2019 Aug 29 doi: 10.12688/f1000research.18900.1. PMID: 31508201Free PMC Article

Therapy

Zhang B, Hu Y, Shi X, Li W, Zeng X, Liu F, Chen JDZ, Xie WF
Am J Gastroenterol 2021 Jul 1;116(7):1495-1505. doi: 10.14309/ajg.0000000000001203. PMID: 34183577
Wilkinson JM, Halland M
Am Fam Physician 2020 Sep 1;102(5):291-296. PMID: 32866357
Snyder DL, Vela MF
Curr Opin Gastroenterol 2020 Jul;36(4):344-350. doi: 10.1097/MOG.0000000000000648. PMID: 32427604
Kim JP, Kahrilas PJ
Curr Gastroenterol Rep 2019 Aug 20;21(10):49. doi: 10.1007/s11894-019-0718-1. PMID: 31432250
Savarino E, Marabotto E, Savarino V
Curr Opin Gastroenterol 2018 Jul;34(4):243-248. doi: 10.1097/MOG.0000000000000439. PMID: 29846257

Prognosis

Zheng Z, Shang Y, Wang N, Liu X, Xin C, Yan X, Zhai Y, Yin J, Zhang J, Zhang Z
Int J Biol Sci 2021;17(15):4154-4164. Epub 2021 Oct 3 doi: 10.7150/ijbs.65066. PMID: 34803489Free PMC Article
Wong D, Chan WW
Curr Gastroenterol Rep 2021 Oct 15;23(12):23. doi: 10.1007/s11894-021-00824-3. PMID: 34654956
Laliberte AS, Louie BE, Wilshire CL, Farivar AS, Bograd AJ, Aye RW
Surg Endosc 2021 Aug;35(8):4811-4816. Epub 2020 Aug 13 doi: 10.1007/s00464-020-07883-z. PMID: 32794047
Kim JP, Kahrilas PJ
Curr Gastroenterol Rep 2019 Aug 20;21(10):49. doi: 10.1007/s11894-019-0718-1. PMID: 31432250
Kruger D
JAAPA 2014 May;27(5):23-30. doi: 10.1097/01.JAA.0000446227.85554.fb. PMID: 24691181

Clinical prediction guides

Zhang B, Hu Y, Shi X, Li W, Zeng X, Liu F, Chen JDZ, Xie WF
Am J Gastroenterol 2021 Jul 1;116(7):1495-1505. doi: 10.14309/ajg.0000000000001203. PMID: 34183577
Achem SR, Vazquez-Elizondo G, Fass R
J Clin Gastroenterol 2021 May-Jun 01;55(5):369-379. doi: 10.1097/MCG.0000000000001472. PMID: 33337637
Laliberte AS, Louie BE, Wilshire CL, Farivar AS, Bograd AJ, Aye RW
Surg Endosc 2021 Aug;35(8):4811-4816. Epub 2020 Aug 13 doi: 10.1007/s00464-020-07883-z. PMID: 32794047
Hani A, Zuluaga C, Costa V, Leguizamo AM, Puentes G, Ardila AF, Achem SR
Rev Gastroenterol Mex (Engl Ed) 2020 Oct-Dec;85(4):421-427. Epub 2020 Jan 6 doi: 10.1016/j.rgmx.2019.11.002. PMID: 31917034
Yadlapati R
Curr Opin Gastroenterol 2017 Jul;33(4):301-309. doi: 10.1097/MOG.0000000000000369. PMID: 28426462Free PMC Article

Recent systematic reviews

McKinley SK, Dirks RC, Walsh D, Hollands C, Arthur LE, Rodriguez N, Jhang J, Abou-Setta A, Pryor A, Stefanidis D, Slater BJ
Surg Endosc 2021 Aug;35(8):4095-4123. Epub 2021 Mar 2 doi: 10.1007/s00464-021-08358-5. PMID: 33651167
Eusebi LH, Ratnakumaran R, Yuan Y, Solaymani-Dodaran M, Bazzoli F, Ford AC
Gut 2018 Mar;67(3):430-440. Epub 2017 Feb 23 doi: 10.1136/gutjnl-2016-313589. PMID: 28232473
Ness-Jensen E, Hveem K, El-Serag H, Lagergren J
Clin Gastroenterol Hepatol 2016 Feb;14(2):175-82.e1-3. Epub 2015 May 6 doi: 10.1016/j.cgh.2015.04.176. PMID: 25956834Free PMC Article
Pandolfino JE, Gawron AJ
JAMA 2015 May 12;313(18):1841-52. doi: 10.1001/jama.2015.2996. PMID: 25965233
Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R; Global Consensus Group
Am J Gastroenterol 2006 Aug;101(8):1900-20; quiz 1943. doi: 10.1111/j.1572-0241.2006.00630.x. PMID: 16928254

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...