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Ulcerative Colitis-Associated Colorectal Adenocarcinoma

MedGen UID:
474453
Concept ID:
C3272820
Neoplastic Process
Synonyms: UC-Associated CRC; Ulcerative Colitis-Associated Colorectal Carcinoma

Definition

A colorectal adenocarcinoma that develops in patients with a history of ulcerative colitis. Such carcinomas are usually multiple and flat. Histologically, they are usually mucinous or signet-ring cell type. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUlcerative Colitis-Associated Colorectal Adenocarcinoma

Recent clinical studies

Etiology

Uchino M, Ikeuchi H, Noguchi T, Okabayashi K, Futami K, Tanaka S, Ohge H, Watanabe K, Itabashi M, Okamoto K, Okita Y, Mizushima T, Mizuuchi Y, Yamada K, Shimada Y, Sato Y, Kimura H, Takahashi K, Hida K, Kinugasa Y, Okuda J, Daito K, Koyama F, Ueno H, Yamamoto T, Hanai T, Kono T, Kobayashi H, Ajioka Y, Sugihara K, Ishihara S; Study Group for Inflammatory Bowel Disease Associated Intestinal Cancers of the Japanese Society for Cancer of the Colon and Rectum
J Gastroenterol Hepatol 2024 May;39(5):893-901. Epub 2024 Jan 25 doi: 10.1111/jgh.16496. PMID: 38273469
Yashiro M
World J Gastroenterol 2014 Nov 28;20(44):16389-97. doi: 10.3748/wjg.v20.i44.16389. PMID: 25469007Free PMC Article
Jawad N, Direkze N, Leedham SJ
Recent Results Cancer Res 2011;185:99-115. doi: 10.1007/978-3-642-03503-6_6. PMID: 21822822
Triantafillidis JK, Nasioulas G, Kosmidis PA
Anticancer Res 2009 Jul;29(7):2727-37. PMID: 19596953
Xie J, Itzkowitz SH
World J Gastroenterol 2008 Jan 21;14(3):378-89. doi: 10.3748/wjg.14.378. PMID: 18200660Free PMC Article

Diagnosis

Uchino M, Ikeuchi H, Noguchi T, Okabayashi K, Futami K, Tanaka S, Ohge H, Watanabe K, Itabashi M, Okamoto K, Okita Y, Mizushima T, Mizuuchi Y, Yamada K, Shimada Y, Sato Y, Kimura H, Takahashi K, Hida K, Kinugasa Y, Okuda J, Daito K, Koyama F, Ueno H, Yamamoto T, Hanai T, Kono T, Kobayashi H, Ajioka Y, Sugihara K, Ishihara S; Study Group for Inflammatory Bowel Disease Associated Intestinal Cancers of the Japanese Society for Cancer of the Colon and Rectum
J Gastroenterol Hepatol 2024 May;39(5):893-901. Epub 2024 Jan 25 doi: 10.1111/jgh.16496. PMID: 38273469
Saraggi D, Fassan M, Mescoli C, Scarpa M, Valeri N, Michielan A, D'Incá R, Rugge M
Dig Liver Dis 2017 Apr;49(4):326-330. Epub 2016 Dec 21 doi: 10.1016/j.dld.2016.12.011. PMID: 28089111
Yashiro M
World J Gastroenterol 2014 Nov 28;20(44):16389-97. doi: 10.3748/wjg.v20.i44.16389. PMID: 25469007Free PMC Article
Oka S, Tanaka S, Chayama K
Gastrointest Endosc Clin N Am 2014 Jul;24(3):405-17. doi: 10.1016/j.giec.2014.03.011. PMID: 24975531
Jawad N, Direkze N, Leedham SJ
Recent Results Cancer Res 2011;185:99-115. doi: 10.1007/978-3-642-03503-6_6. PMID: 21822822

Therapy

Yoon YS, Cho YB, Park KJ, Baik SH, Yoon SN, Ryoo SB, Lee KY, Kim H, Lee RA, Yu CS; IBD Study Group; Korean Society of Coloproctology
World J Gastroenterol 2015 Mar 28;21(12):3547-53. doi: 10.3748/wjg.v21.i12.3547. PMID: 25834319Free PMC Article
Yashiro M
World J Gastroenterol 2014 Nov 28;20(44):16389-97. doi: 10.3748/wjg.v20.i44.16389. PMID: 25469007Free PMC Article
Oka S, Tanaka S, Chayama K
Gastrointest Endosc Clin N Am 2014 Jul;24(3):405-17. doi: 10.1016/j.giec.2014.03.011. PMID: 24975531
Herfarth H
Dig Dis 2012;30 Suppl 2:55-9. Epub 2012 Nov 23 doi: 10.1159/000341894. PMID: 23207933
Xie J, Itzkowitz SH
World J Gastroenterol 2008 Jan 21;14(3):378-89. doi: 10.3748/wjg.14.378. PMID: 18200660Free PMC Article

Prognosis

Saraggi D, Fassan M, Mescoli C, Scarpa M, Valeri N, Michielan A, D'Incá R, Rugge M
Dig Liver Dis 2017 Apr;49(4):326-330. Epub 2016 Dec 21 doi: 10.1016/j.dld.2016.12.011. PMID: 28089111
Liu G, Lin J, Xie H, Shen B, Stocchi L, Liu X
Scand J Gastroenterol 2015;50(11):1389-96. Epub 2015 Jun 10 doi: 10.3109/00365521.2015.1052094. PMID: 26061393
Yashiro M
World J Gastroenterol 2014 Nov 28;20(44):16389-97. doi: 10.3748/wjg.v20.i44.16389. PMID: 25469007Free PMC Article
Jawad N, Direkze N, Leedham SJ
Recent Results Cancer Res 2011;185:99-115. doi: 10.1007/978-3-642-03503-6_6. PMID: 21822822
Triantafillidis JK, Nasioulas G, Kosmidis PA
Anticancer Res 2009 Jul;29(7):2727-37. PMID: 19596953

Clinical prediction guides

Uchino M, Ikeuchi H, Noguchi T, Okabayashi K, Futami K, Tanaka S, Ohge H, Watanabe K, Itabashi M, Okamoto K, Okita Y, Mizushima T, Mizuuchi Y, Yamada K, Shimada Y, Sato Y, Kimura H, Takahashi K, Hida K, Kinugasa Y, Okuda J, Daito K, Koyama F, Ueno H, Yamamoto T, Hanai T, Kono T, Kobayashi H, Ajioka Y, Sugihara K, Ishihara S; Study Group for Inflammatory Bowel Disease Associated Intestinal Cancers of the Japanese Society for Cancer of the Colon and Rectum
J Gastroenterol Hepatol 2024 May;39(5):893-901. Epub 2024 Jan 25 doi: 10.1111/jgh.16496. PMID: 38273469
Uragami T, Ando Y, Aoi M, Fukui T, Matsumoto Y, Horitani S, Tomiyama T, Okazaki K, Tsuneyama K, Tanaka H, Naganuma M
Dig Dis Sci 2023 May;68(5):1885-1893. Epub 2022 Dec 11 doi: 10.1007/s10620-022-07774-4. PMID: 36504013
Kobayashi K, Kawagishi K, Ooka S, Yokoyama K, Sada M, Koizumi W
World J Gastroenterol 2015 Mar 7;21(9):2693-9. doi: 10.3748/wjg.v21.i9.2693. PMID: 25759538Free PMC Article
Yashiro M
World J Gastroenterol 2014 Nov 28;20(44):16389-97. doi: 10.3748/wjg.v20.i44.16389. PMID: 25469007Free PMC Article
Herfarth H
Dig Dis 2012;30 Suppl 2:55-9. Epub 2012 Nov 23 doi: 10.1159/000341894. PMID: 23207933

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