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Gallbladder Neuroendocrine Tumor G1

MedGen UID:
474752
•Concept ID:
C3273119
•
Neoplastic Process
Synonyms: Gallbladder Carcinoid Tumor; Gallbladder NET G1

Definition

A well differentiated, low grade neuroendocrine neoplasm (carcinoid tumor) that arises from the gallbladder. The mitotic count is less than 2 per 10 HPF and/or the Ki67 index is equal to or less than 2 percent. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGallbladder Neuroendocrine Tumor G1

Professional guidelines

PubMed

Clinicopathological Findings and Treatment Outcomes of Patients with Primary Hepatobiliary Neuroendocrine Neoplasms: A Retrospective Single-institution Analysis.
Komiyama S, Okusaka T, Maruki Y, Ohba A, Nagashio Y, Kondo S, Hijioka S, Morizane C, Ueno H, Sukeda A, Mizui T, Takamoto T, Nara S, Ban D, Esaki M, Hiraoka N, Shimada K
Intern Med 2024 Apr 1;63(7):891-901. Epub 2023 Aug 23 doi: 10.2169/internalmedicine.2016-23. PMID: 37612088Free PMC Article

Recent clinical studies

Etiology

Clinicopathological Findings and Treatment Outcomes of Patients with Primary Hepatobiliary Neuroendocrine Neoplasms: A Retrospective Single-institution Analysis.
Komiyama S, Okusaka T, Maruki Y, Ohba A, Nagashio Y, Kondo S, Hijioka S, Morizane C, Ueno H, Sukeda A, Mizui T, Takamoto T, Nara S, Ban D, Esaki M, Hiraoka N, Shimada K
Intern Med 2024 Apr 1;63(7):891-901. Epub 2023 Aug 23 doi: 10.2169/internalmedicine.2016-23. PMID: 37612088Free PMC Article
Biodistribution of (18)F-AlF-NOTA-octreotide in Different Organs and Characterization of Uptake in Neuroendocrine Neoplasms.
Hou J, Long T, Yang N, Chen D, Zeng S, Zheng K, Liao G, Hu S
Mol Imaging Biol 2021 Dec;23(6):827-835. Epub 2021 Jul 6 doi: 10.1007/s11307-021-01628-7. PMID: 34231107
Detection of NRG1 Gene Fusions in Solid Tumors.
Jonna S, Feldman RA, Swensen J, Gatalica Z, Korn WM, Borghaei H, Ma PC, Nieva JJ, Spira AI, Vanderwalde AM, Wozniak AJ, Kim ES, Liu SV
Clin Cancer Res 2019 Aug 15;25(16):4966-4972. Epub 2019 Apr 15 doi: 10.1158/1078-0432.CCR-19-0160. PMID: 30988082Free PMC Article
18F-fluorodihydroxyphenylalanine PET/CT in patients with neuroendocrine tumors of unknown origin: relation to tumor origin and differentiation.
Imperiale A, Rust E, Gabriel S, Detour J, Goichot B, Duclos B, Kurtz JE, Bachellier P, Namer IJ, Taïeb D
J Nucl Med 2014 Mar;55(3):367-72. Epub 2013 Dec 16 doi: 10.2967/jnumed.113.126896. PMID: 24343986

Diagnosis

Clinicopathological Findings and Treatment Outcomes of Patients with Primary Hepatobiliary Neuroendocrine Neoplasms: A Retrospective Single-institution Analysis.
Komiyama S, Okusaka T, Maruki Y, Ohba A, Nagashio Y, Kondo S, Hijioka S, Morizane C, Ueno H, Sukeda A, Mizui T, Takamoto T, Nara S, Ban D, Esaki M, Hiraoka N, Shimada K
Intern Med 2024 Apr 1;63(7):891-901. Epub 2023 Aug 23 doi: 10.2169/internalmedicine.2016-23. PMID: 37612088Free PMC Article
G1-Neuroendocrine tumor of gallbladder with unique dendritic morphology.
Ichimaru C, Ishii T, Katanuma A
J Hepatobiliary Pancreat Sci 2022 Oct;29(10):e100-e103. Epub 2022 May 5 doi: 10.1002/jhbp.1153. PMID: 35510353
Biodistribution of (18)F-AlF-NOTA-octreotide in Different Organs and Characterization of Uptake in Neuroendocrine Neoplasms.
Hou J, Long T, Yang N, Chen D, Zeng S, Zheng K, Liao G, Hu S
Mol Imaging Biol 2021 Dec;23(6):827-835. Epub 2021 Jul 6 doi: 10.1007/s11307-021-01628-7. PMID: 34231107
Clear cell neuroendocrine tumor in the gallbladder diagnosed as a benign polyp preoperatively: a case report.
Sumiya R, Shimizu A, Nagai T, Ono H, Kumazawa K, Endo D, Oide T, Aoyanagi N
World J Surg Oncol 2021 Jan 2;19(1):3. doi: 10.1186/s12957-020-02104-2. PMID: 33388069Free PMC Article
18F-fluorodihydroxyphenylalanine PET/CT in patients with neuroendocrine tumors of unknown origin: relation to tumor origin and differentiation.
Imperiale A, Rust E, Gabriel S, Detour J, Goichot B, Duclos B, Kurtz JE, Bachellier P, Namer IJ, Taïeb D
J Nucl Med 2014 Mar;55(3):367-72. Epub 2013 Dec 16 doi: 10.2967/jnumed.113.126896. PMID: 24343986

Prognosis

Clinicopathological Findings and Treatment Outcomes of Patients with Primary Hepatobiliary Neuroendocrine Neoplasms: A Retrospective Single-institution Analysis.
Komiyama S, Okusaka T, Maruki Y, Ohba A, Nagashio Y, Kondo S, Hijioka S, Morizane C, Ueno H, Sukeda A, Mizui T, Takamoto T, Nara S, Ban D, Esaki M, Hiraoka N, Shimada K
Intern Med 2024 Apr 1;63(7):891-901. Epub 2023 Aug 23 doi: 10.2169/internalmedicine.2016-23. PMID: 37612088Free PMC Article
Clear cell neuroendocrine tumor in the gallbladder diagnosed as a benign polyp preoperatively: a case report.
Sumiya R, Shimizu A, Nagai T, Ono H, Kumazawa K, Endo D, Oide T, Aoyanagi N
World J Surg Oncol 2021 Jan 2;19(1):3. doi: 10.1186/s12957-020-02104-2. PMID: 33388069Free PMC Article

Clinical prediction guides

Clinicopathological Findings and Treatment Outcomes of Patients with Primary Hepatobiliary Neuroendocrine Neoplasms: A Retrospective Single-institution Analysis.
Komiyama S, Okusaka T, Maruki Y, Ohba A, Nagashio Y, Kondo S, Hijioka S, Morizane C, Ueno H, Sukeda A, Mizui T, Takamoto T, Nara S, Ban D, Esaki M, Hiraoka N, Shimada K
Intern Med 2024 Apr 1;63(7):891-901. Epub 2023 Aug 23 doi: 10.2169/internalmedicine.2016-23. PMID: 37612088Free PMC Article
Biodistribution of (18)F-AlF-NOTA-octreotide in Different Organs and Characterization of Uptake in Neuroendocrine Neoplasms.
Hou J, Long T, Yang N, Chen D, Zeng S, Zheng K, Liao G, Hu S
Mol Imaging Biol 2021 Dec;23(6):827-835. Epub 2021 Jul 6 doi: 10.1007/s11307-021-01628-7. PMID: 34231107
Clear cell neuroendocrine tumor in the gallbladder diagnosed as a benign polyp preoperatively: a case report.
Sumiya R, Shimizu A, Nagai T, Ono H, Kumazawa K, Endo D, Oide T, Aoyanagi N
World J Surg Oncol 2021 Jan 2;19(1):3. doi: 10.1186/s12957-020-02104-2. PMID: 33388069Free PMC Article

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