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Sclerosing Polycystic Adenosis

MedGen UID:
474884
Concept ID:
C3273251
Neoplastic Process
Synonym: Salivary Gland Sclerosing Polycystic Adenosis

Definition

A rare, benign, well-circumscribed salivary gland neoplasm that predominantly affects females. It is characterized by the presence of microcysts, ducts, and acini in a sclerotic stroma. Focal lymphocytic infiltrates may also be present. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSclerosing Polycystic Adenosis

Recent clinical studies

Etiology

Henrique Braz-Silva P, Motta do Canto A, Oliveira L, Martins F, Antônio Pereira da Costa A, Adolfo Costa Hanemann J
Bull Tokyo Dent Coll 2018;59(2):121-125. doi: 10.2209/tdcpublication.2017-0029. PMID: 29962419
Skálová A, Gnepp DR, Lewis JS Jr, Hunt JL, Bishop JA, Hellquist H, Rinaldo A, Vander Poorten V, Ferlito A
Am J Surg Pathol 2017 Aug;41(8):e33-e47. doi: 10.1097/PAS.0000000000000883. PMID: 28614209
Perottino F, Barnoud R, Ambrun A, Poupart M, Pignat JC, Merrot O
Eur Ann Otorhinolaryngol Head Neck Dis 2010 Mar;127(1):20-2. Epub 2010 Mar 24 doi: 10.1016/j.anorl.2010.02.005. PMID: 20822751
Etit D, Pilch BZ, Osgood R, Faquin WC
Diagn Cytopathol 2007 Jul;35(7):444-7. doi: 10.1002/dc.20671. PMID: 17580340
Smith BC, Ellis GL, Slater LJ, Foss RD
Am J Surg Pathol 1996 Feb;20(2):161-70. doi: 10.1097/00000478-199602000-00004. PMID: 8554105

Diagnosis

Petersson F
Ann Diagn Pathol 2022 Aug;59:151949. Epub 2022 Apr 9 doi: 10.1016/j.anndiagpath.2022.151949. PMID: 35447367
Bishop JA, Thompson LDR
Surg Pathol Clin 2021 Mar;14(1):17-24. doi: 10.1016/j.path.2020.09.004. PMID: 33526220
Espinosa CA, Rua L, Torres HE, Fernández Del Valle Á, Fernandes RP, Devicente JC
J Oral Maxillofac Surg 2017 May;75(5):984-993. Epub 2016 Nov 2 doi: 10.1016/j.joms.2016.10.031. PMID: 27888671
Chan JK
Int J Surg Pathol 2014 Feb;22(1):12-32. Epub 2014 Jan 9 doi: 10.1177/1066896913517939. PMID: 24406626
Eliot CA, Smith AB, Foss RD
Head Neck Pathol 2012 Jun;6(2):247-9. Epub 2011 Dec 20 doi: 10.1007/s12105-011-0317-4. PMID: 22183766Free PMC Article

Therapy

Petersson F
Head Neck Pathol 2013 Jul;7 Suppl 1(Suppl 1):S97-106. Epub 2013 Jul 3 doi: 10.1007/s12105-013-0465-9. PMID: 23821217Free PMC Article
Skálová A, Gnepp DR, Simpson RH, Lewis JE, Janssen D, Sima R, Vanecek T, Di Palma S, Michal M
Am J Surg Pathol 2006 Aug;30(8):939-44. doi: 10.1097/00000478-200608000-00002. PMID: 16861963

Prognosis

de Carvalho Kimura T, de Lima-Souza RA, Scarini JF, Lavareze L, Egal ESA, Altemani A, Mariano FV
Head Neck 2023 Sep;45(9):2449-2457. Epub 2023 Jul 5 doi: 10.1002/hed.27435. PMID: 37403748
Bishop JA, Thompson LDR
Surg Pathol Clin 2021 Mar;14(1):17-24. doi: 10.1016/j.path.2020.09.004. PMID: 33526220
Henrique Braz-Silva P, Motta do Canto A, Oliveira L, Martins F, Antônio Pereira da Costa A, Adolfo Costa Hanemann J
Bull Tokyo Dent Coll 2018;59(2):121-125. doi: 10.2209/tdcpublication.2017-0029. PMID: 29962419
Skálová A, Gnepp DR, Lewis JS Jr, Hunt JL, Bishop JA, Hellquist H, Rinaldo A, Vander Poorten V, Ferlito A
Am J Surg Pathol 2017 Aug;41(8):e33-e47. doi: 10.1097/PAS.0000000000000883. PMID: 28614209
Cheuk W, Chan JK
Histopathology 2007 Jul;51(1):1-20. Epub 2007 May 31 doi: 10.1111/j.1365-2559.2007.02719.x. PMID: 17539914

Clinical prediction guides

Uemura A, Bandoh N, Goto T, Sato R, Suzuki S, Kubota A, Yamaguchi T, Baba S, Kato Y, Nishihara H, Harabuchi Y, Takei H
Head Neck Pathol 2022 Mar;16(1):282-287. Epub 2021 Jun 2 doi: 10.1007/s12105-021-01339-z. PMID: 34076847Free PMC Article
Kawai M, Inoue T, Yonaga T, Mochizuki K, Nakazawa T, Masuyama K, Kondo T
Diagn Cytopathol 2019 Nov;47(11):1208-1212. Epub 2019 Jul 22 doi: 10.1002/dc.24283. PMID: 31329351
Henrique Braz-Silva P, Motta do Canto A, Oliveira L, Martins F, Antônio Pereira da Costa A, Adolfo Costa Hanemann J
Bull Tokyo Dent Coll 2018;59(2):121-125. doi: 10.2209/tdcpublication.2017-0029. PMID: 29962419
Chan JK
Int J Surg Pathol 2014 Feb;22(1):12-32. Epub 2014 Jan 9 doi: 10.1177/1066896913517939. PMID: 24406626
Cheuk W, Chan JK
Histopathology 2007 Jul;51(1):1-20. Epub 2007 May 31 doi: 10.1111/j.1365-2559.2007.02719.x. PMID: 17539914

Recent systematic reviews

de Carvalho Kimura T, de Lima-Souza RA, Scarini JF, Lavareze L, Egal ESA, Altemani A, Mariano FV
Head Neck 2023 Sep;45(9):2449-2457. Epub 2023 Jul 5 doi: 10.1002/hed.27435. PMID: 37403748
Espinosa CA, Rua L, Torres HE, Fernández Del Valle Á, Fernandes RP, Devicente JC
J Oral Maxillofac Surg 2017 May;75(5):984-993. Epub 2016 Nov 2 doi: 10.1016/j.joms.2016.10.031. PMID: 27888671

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