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Stress Disorders, Traumatic

MedGen UID:
52520
•Concept ID:
C0038441
•
Mental or Behavioral Dysfunction
Synonyms: Stress Disorder, Traumatic; Traumatic Stress Disorder; Traumatic Stress Disorders

Definition

Anxiety disorders manifested by the development of characteristic symptoms following a psychologically traumatic event that is outside the normal range of usual human experience. Symptoms include re-experiencing the traumatic event, increased arousal, and numbing of responsiveness to or reduced involvement with the external world. Traumatic stress disorders can be further classified by the time of onset and the duration of these symptoms. [from MeSH]

Professional guidelines

PubMed

Treatment of Post-Traumatic Stress Disorders with the Alpha-1 Adrenergic Antagonist Prazosin.
Simon PY, Rousseau PF
Can J Psychiatry 2017 Mar;62(3):186-198. Epub 2016 Jul 19 doi: 10.1177/0706743716659275. PMID: 27432823Free PMC Article
Epigenetic Treatment of Neurodegenerative Disorders: Alzheimer and Parkinson Diseases.
Irwin MH, Moos WH, Faller DV, Steliou K, Pinkert CA
Drug Dev Res 2016 May;77(3):109-23. Epub 2016 Feb 21 doi: 10.1002/ddr.21294. PMID: 26899010
Orexins and fear: implications for the treatment of anxiety disorders.
Flores Á, Saravia R, Maldonado R, Berrendero F
Trends Neurosci 2015 Sep;38(9):550-9. Epub 2015 Jul 24 doi: 10.1016/j.tins.2015.06.005. PMID: 26216377

Recent clinical studies

Etiology

Cardiac disease-induced trauma and stress-related disorders.
Princip M, Ledermann K, Altwegg R, von Känel R
Herz 2024 Aug;49(4):254-260. Epub 2024 Jul 11 doi: 10.1007/s00059-024-05255-0. PMID: 38990256Free PMC Article
Pharmacological prevention and early treatment of post-traumatic stress disorder and acute stress disorder: a systematic review and meta-analysis.
Astill Wright L, Sijbrandij M, Sinnerton R, Lewis C, Roberts NP, Bisson JI
Transl Psychiatry 2019 Dec 9;9(1):334. doi: 10.1038/s41398-019-0673-5. PMID: 31819037Free PMC Article
Trauma and Aging.
Cook JM, Simiola V
Curr Psychiatry Rep 2018 Sep 7;20(10):93. doi: 10.1007/s11920-018-0943-6. PMID: 30194546
Indicated and selective preventive interventions.
Marsac ML, Donlon K, Berkowitz S
Child Adolesc Psychiatr Clin N Am 2014 Apr;23(2):383-97, x. Epub 2014 Feb 19 doi: 10.1016/j.chc.2013.12.001. PMID: 24656586
Freeze, flight, fight, fright, faint: adaptationist perspectives on the acute stress response spectrum.
Bracha HS
CNS Spectr 2004 Sep;9(9):679-85. doi: 10.1017/s1092852900001954. PMID: 15337864

Diagnosis

The Management of Posttraumatic Stress Disorder and Acute Stress Disorder: Synopsis of the 2023 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline.
Schnurr PP, Hamblen JL, Wolf J, Coller R, Collie C, Fuller MA, Holtzheimer PE, Kelly U, Lang AJ, McGraw K, Morganstein JC, Norman SB, Papke K, Petrakis I, Riggs D, Sall JA, Shiner B, Wiechers I, Kelber MS
Ann Intern Med 2024 Mar;177(3):363-374. Epub 2024 Feb 27 doi: 10.7326/M23-2757. PMID: 38408360
Association of Stress-Related Disorders With Subsequent Autoimmune Disease.
Song H, Fang F, Tomasson G, Arnberg FK, Mataix-Cols D, Fernández de la Cruz L, Almqvist C, Fall K, Valdimarsdóttir UA
JAMA 2018 Jun 19;319(23):2388-2400. doi: 10.1001/jama.2018.7028. PMID: 29922828Free PMC Article
Complex trauma.
Kliethermes M, Schacht M, Drewry K
Child Adolesc Psychiatr Clin N Am 2014 Apr;23(2):339-61, ix. Epub 2014 Feb 16 doi: 10.1016/j.chc.2013.12.009. PMID: 24656584
Special issue on posttraumatic, stress-related, and dissociative disorders.
Friedman MJ
Depress Anxiety 2011 Sep;28(9):735-6. doi: 10.1002/da.20893. PMID: 21910183
Freeze, flight, fight, fright, faint: adaptationist perspectives on the acute stress response spectrum.
Bracha HS
CNS Spectr 2004 Sep;9(9):679-85. doi: 10.1017/s1092852900001954. PMID: 15337864

Therapy

Food-Derived Opioid Peptides in Human Health: A Review.
Tyagi A, Daliri EB, Kwami Ofosu F, Yeon SJ, Oh DH
Int J Mol Sci 2020 Nov 21;21(22) doi: 10.3390/ijms21228825. PMID: 33233481Free PMC Article
Association of Stress-Related Disorders With Subsequent Autoimmune Disease.
Song H, Fang F, Tomasson G, Arnberg FK, Mataix-Cols D, Fernández de la Cruz L, Almqvist C, Fall K, Valdimarsdóttir UA
JAMA 2018 Jun 19;319(23):2388-2400. doi: 10.1001/jama.2018.7028. PMID: 29922828Free PMC Article
Cognitive behavioral therapy for anxiety and related disorders: A meta-analysis of randomized placebo-controlled trials.
Carpenter JK, Andrews LA, Witcraft SM, Powers MB, Smits JAJ, Hofmann SG
Depress Anxiety 2018 Jun;35(6):502-514. Epub 2018 Feb 16 doi: 10.1002/da.22728. PMID: 29451967Free PMC Article
Prevention of Trauma and Stressor-Related Disorders: A Review.
Howlett JR, Stein MB
Neuropsychopharmacology 2016 Jan;41(1):357-69. Epub 2015 Aug 28 doi: 10.1038/npp.2015.261. PMID: 26315508Free PMC Article
Posttraumatic stress disorder and stress-related disorders.
Shalev AY
Psychiatr Clin North Am 2009 Sep;32(3):687-704. doi: 10.1016/j.psc.2009.06.001. PMID: 19716997Free PMC Article

Prognosis

Cardiac disease-induced trauma and stress-related disorders.
Princip M, Ledermann K, Altwegg R, von Känel R
Herz 2024 Aug;49(4):254-260. Epub 2024 Jul 11 doi: 10.1007/s00059-024-05255-0. PMID: 38990256Free PMC Article
The Current Evidence for Acute Stress Disorder.
Bryant RA
Curr Psychiatry Rep 2018 Oct 13;20(12):111. doi: 10.1007/s11920-018-0976-x. PMID: 30315408
Association of Stress-Related Disorders With Subsequent Autoimmune Disease.
Song H, Fang F, Tomasson G, Arnberg FK, Mataix-Cols D, Fernández de la Cruz L, Almqvist C, Fall K, Valdimarsdóttir UA
JAMA 2018 Jun 19;319(23):2388-2400. doi: 10.1001/jama.2018.7028. PMID: 29922828Free PMC Article
Acute stress disorder revisited.
Cardeña E, Carlson E
Annu Rev Clin Psychol 2011;7:245-67. doi: 10.1146/annurev-clinpsy-032210-104502. PMID: 21275643
Stress and health: psychological, behavioral, and biological determinants.
Schneiderman N, Ironson G, Siegel SD
Annu Rev Clin Psychol 2005;1:607-28. doi: 10.1146/annurev.clinpsy.1.102803.144141. PMID: 17716101Free PMC Article

Clinical prediction guides

Stress Disorders and Dementia in the Danish Population.
Gradus JL, Horváth-Puhó E, Lash TL, Ehrenstein V, Tamang S, Adler NE, Milstein A, Glymour MM, Henderson VW, Sørensen HT
Am J Epidemiol 2019 Mar 1;188(3):493-499. doi: 10.1093/aje/kwy269. PMID: 30576420Free PMC Article
The Current Evidence for Acute Stress Disorder.
Bryant RA
Curr Psychiatry Rep 2018 Oct 13;20(12):111. doi: 10.1007/s11920-018-0976-x. PMID: 30315408
Suicide among war veterans.
Rozanov V, Carli V
Int J Environ Res Public Health 2012 Jul;9(7):2504-19. Epub 2012 Jul 19 doi: 10.3390/ijerph9072504. PMID: 22851956Free PMC Article
Psychopathy and traumatic stress.
Pham TH
J Pers Disord 2012 Apr;26(2):213-25. doi: 10.1521/pedi.2012.26.2.213. PMID: 22486451
Acute stress disorder revisited.
Cardeña E, Carlson E
Annu Rev Clin Psychol 2011;7:245-67. doi: 10.1146/annurev-clinpsy-032210-104502. PMID: 21275643

Recent systematic reviews

The effect of lavender on stress in individuals: A systematic review and meta-analysis.
Ghavami T, Kazeminia M, Rajati F
Complement Ther Med 2022 Sep;68:102832. Epub 2022 Apr 13 doi: 10.1016/j.ctim.2022.102832. PMID: 35429599
Systematic Review and Meta-Analysis on Acute Stress Disorder: Rates Following Different Types of Traumatic Events.
Geoffrion S, Goncalves J, Robichaud I, Sader J, Giguère CÉ, Fortin M, Lamothe J, Bernard P, Guay S
Trauma Violence Abuse 2022 Jan;23(1):213-223. Epub 2020 Jun 26 doi: 10.1177/1524838020933844. PMID: 32588756
Pharmacological prevention and early treatment of post-traumatic stress disorder and acute stress disorder: a systematic review and meta-analysis.
Astill Wright L, Sijbrandij M, Sinnerton R, Lewis C, Roberts NP, Bisson JI
Transl Psychiatry 2019 Dec 9;9(1):334. doi: 10.1038/s41398-019-0673-5. PMID: 31819037Free PMC Article
Pharmacological prevention of post-traumatic stress disorder and acute stress disorder: a systematic review and meta-analysis.
Sijbrandij M, Kleiboer A, Bisson JI, Barbui C, Cuijpers P
Lancet Psychiatry 2015 May;2(5):413-421. Epub 2015 Apr 28 doi: 10.1016/S2215-0366(14)00121-7. PMID: 26360285
Secondary traumatic stress in nurses: a systematic review.
Beck CT
Arch Psychiatr Nurs 2011 Feb;25(1):1-10. Epub 2010 Jul 23 doi: 10.1016/j.apnu.2010.05.005. PMID: 21251596

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