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Benign neoplasm of retina

MedGen UID:
57580
•Concept ID:
C0154027
•
Neoplastic Process
Synonyms: Benign Neoplasm of Retina; benign neoplasm of retina; Benign Neoplasm of the Retina; benign neoplasm of the retina; Benign Retina Neoplasm; benign retina neoplasm; Benign Retina Tumor; benign retina tumor; benign retina tumour; Benign Retinal Neoplasm; benign retinal neoplasm; Benign retinal tumor; Benign Retinal Tumor; benign retinal tumor; benign retinal tumour; Benign tumor of retina; Benign Tumor of Retina; benign tumor of retina; Benign Tumor of the Retina; benign tumor of the retina; benign tumour of retina; benign tumour of the retina; retina benign neoplasm
SNOMED CT: Benign neoplasm of retina (92321003); Benign retinal tumor (92321003); Benign tumor of retina (92321003)
 
Monarch Initiative: MONDO:0021453

Definition

A neoplasm that arises from the retina and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of retina

Professional guidelines

PubMed

Updated International Tuberous Sclerosis Complex Diagnostic Criteria and Surveillance and Management Recommendations.
Northrup H, Aronow ME, Bebin EM, Bissler J, Darling TN, de Vries PJ, Frost MD, Fuchs Z, Gosnell ES, Gupta N, Jansen AC, Jóźwiak S, Kingswood JC, Knilans TK, McCormack FX, Pounders A, Roberds SL, Rodriguez-Buritica DF, Roth J, Sampson JR, Sparagana S, Thiele EA, Weiner HL, Wheless JW, Towbin AJ, Krueger DA; International Tuberous Sclerosis Complex Consensus Group
Pediatr Neurol 2021 Oct;123:50-66. Epub 2021 Jul 24 doi: 10.1016/j.pediatrneurol.2021.07.011. PMID: 34399110
Primary vitreoretinal lymphoma: a diagnostic and management challenge.
Soussain C, Malaise D, Cassoux N
Blood 2021 Oct 28;138(17):1519-1534. doi: 10.1182/blood.2020008235. PMID: 34036310
Consensus Recommendations for the Diagnosis of Vitreoretinal Lymphoma.
Carbonell D, Mahajan S, Chee SP, Sobolewska B, Agrawal R, Bülow T, Gupta V, Jones NP, Accorinti M, Agarwal M, Batchelor T, Biswas J, Cimino L, tenDam-van Loon NH, de-la-Torre A, Frenkel S, Pe'er J, Kramer M, Miserocchi E, Mochizuki M, Ness T, Rosenbaum JT, Sen HN, Simion M (VRL patient), Sitter H, Vasconcelos-Santos DV, Habot-Wilner Z, Coupland SE, Pulido JS, Smith J, Thorne JE, Zierhut M; Study Group for Vitreoretinal Lymphoma Diagnostics
Ocul Immunol Inflamm 2021 Apr 3;29(3):507-520. Epub 2021 May 19 doi: 10.1080/09273948.2021.1878233. PMID: 34009095

Recent clinical studies

Etiology

Primary vitreoretinal lymphoma: a diagnostic and management challenge.
Soussain C, Malaise D, Cassoux N
Blood 2021 Oct 28;138(17):1519-1534. doi: 10.1182/blood.2020008235. PMID: 34036310
Epiretinal membrane: A review.
Fung AT, Galvin J, Tran T
Clin Exp Ophthalmol 2021 Apr;49(3):289-308. Epub 2021 Mar 24 doi: 10.1111/ceo.13914. PMID: 33656784
TRPM Channels in Human Diseases.
Jimenez I, Prado Y, Marchant F, Otero C, Eltit F, Cabello-Verrugio C, Cerda O, Simon F
Cells 2020 Dec 4;9(12) doi: 10.3390/cells9122604. PMID: 33291725Free PMC Article
Torpedo maculopathy.
Teitelbaum BA, Hachey DL, Messner LV
J Am Optom Assoc 1997 Jun;68(6):373-6. PMID: 9190137
Ocular choristomas.
Mansour AM, Barber JC, Reinecke RD, Wang FM
Surv Ophthalmol 1989 Mar-Apr;33(5):339-58. doi: 10.1016/0039-6257(89)90011-8. PMID: 2655139

Diagnosis

Hamartomas of the Retina and Optic Disc.
Mirzayev I, Gündüz AK
Turk J Ophthalmol 2022 Dec 28;52(6):421-431. doi: 10.4274/tjo.galenos.2022.25979. PMID: 36578224Free PMC Article
Primary vitreoretinal lymphoma: a diagnostic and management challenge.
Soussain C, Malaise D, Cassoux N
Blood 2021 Oct 28;138(17):1519-1534. doi: 10.1182/blood.2020008235. PMID: 34036310
Intraocular Tumors: Angiographic Patterns.
Bowen RC, Raval V, Soto H, Singh AD
Asia Pac J Ophthalmol (Phila) 2020 Sep-Oct;9(5):449-460. doi: 10.1097/APO.0000000000000323. PMID: 32960821
Pars Plana Cysts.
Kumar V, Kumar P, Roy S, Padhy SK
Ophthalmic Surg Lasers Imaging Retina 2018 Oct 1;49(10):e169-e170. doi: 10.3928/23258160-20181002-24. PMID: 30395682
Retinoblastoma.
Mehta M, Sethi S, Pushker N, Kashyap S, Sen S, Bajaj MS, Ghose S
Singapore Med J 2012 Feb;53(2):128-35; quiz 136. PMID: 22337189

Therapy

Tamoxifen related chorioretinal structural changes.
Erbahçeci Timur İE, Açıkgöz V, Uğurlu N, Yalçın B, Şendur MAN, Hızal M, Kara H
Cutan Ocul Toxicol 2023 Sep;42(3):109-117. Epub 2023 Jun 15 doi: 10.1080/15569527.2023.2220388. PMID: 37272809
Research progress of hydroxychloroquine and autophagy inhibitors on cancer.
Shi TT, Yu XX, Yan LJ, Xiao HT
Cancer Chemother Pharmacol 2017 Feb;79(2):287-294. Epub 2016 Nov 26 doi: 10.1007/s00280-016-3197-1. PMID: 27889812
Lymphoma-associated retinopathy.
To KW, Thirkill CE, Jakobiec FA, Lessell S, Berson EL
Ophthalmology 2002 Nov;109(11):2149-53. doi: 10.1016/s0161-6420(02)01261-7. PMID: 12414431
Cystoid maculopathy.
Irvine AR
Surv Ophthalmol 1976 Jul-Aug;21(1):1-17. doi: 10.1016/0039-6257(76)90045-x. PMID: 785652
Retina and optic nerve.
Campbell FP
Arch Ophthalmol 1968 Jun;79(6):789-802. doi: 10.1001/archopht.1968.03850040791028. PMID: 4385512

Prognosis

Genetics in ophthalmology: molecular blueprints of retinoblastoma.
Marković L, Bukovac A, Varošanec AM, Šlaus N, Pećina-Šlaus N
Hum Genomics 2023 Sep 1;17(1):82. doi: 10.1186/s40246-023-00529-w. PMID: 37658463Free PMC Article
Primary vitreoretinal lymphoma: a diagnostic and management challenge.
Soussain C, Malaise D, Cassoux N
Blood 2021 Oct 28;138(17):1519-1534. doi: 10.1182/blood.2020008235. PMID: 34036310
Epiretinal membrane: A review.
Fung AT, Galvin J, Tran T
Clin Exp Ophthalmol 2021 Apr;49(3):289-308. Epub 2021 Mar 24 doi: 10.1111/ceo.13914. PMID: 33656784
Autoimmune retinopathy.
Grange L, Dalal M, Nussenblatt RB, Sen HN
Am J Ophthalmol 2014 Feb;157(2):266-272.e1. Epub 2013 Sep 29 doi: 10.1016/j.ajo.2013.09.019. PMID: 24315290Free PMC Article
Retinoblastoma.
Mehta M, Sethi S, Pushker N, Kashyap S, Sen S, Bajaj MS, Ghose S
Singapore Med J 2012 Feb;53(2):128-35; quiz 136. PMID: 22337189

Clinical prediction guides

Genetics in ophthalmology: molecular blueprints of retinoblastoma.
Marković L, Bukovac A, Varošanec AM, Šlaus N, Pećina-Šlaus N
Hum Genomics 2023 Sep 1;17(1):82. doi: 10.1186/s40246-023-00529-w. PMID: 37658463Free PMC Article
The role of EZH2 in ocular diseases: a narrative review.
Peng Y, Bui CH, Zhang XJ, Chen JS, Tham CC, Chu WK, Chen LJ, Pang CP, Yam JC
Epigenomics 2023 May;15(9):557-570. Epub 2023 Jul 17 doi: 10.2217/epi-2023-0147. PMID: 37458071
Hamartomas of the Retina and Optic Disc.
Mirzayev I, Gündüz AK
Turk J Ophthalmol 2022 Dec 28;52(6):421-431. doi: 10.4274/tjo.galenos.2022.25979. PMID: 36578224Free PMC Article
Reconstruct Human Retinoblastoma In Vitro.
Zhang X, Jin ZB
J Vis Exp 2022 Oct 11;(188) doi: 10.3791/62629. PMID: 36314812
Epiretinal membrane: A review.
Fung AT, Galvin J, Tran T
Clin Exp Ophthalmol 2021 Apr;49(3):289-308. Epub 2021 Mar 24 doi: 10.1111/ceo.13914. PMID: 33656784

Recent systematic reviews

Clinical features and therapeutic management of choroidal osteoma: A systematic review.
Zhang L, Ran QB, Lei CY, Zhang MX
Surv Ophthalmol 2023 Nov-Dec;68(6):1084-1092. Epub 2023 Jun 14 doi: 10.1016/j.survophthal.2023.06.002. PMID: 37321477
Physiological and pathological functions of βB2-crystallins in multiple organs: a systematic review.
Li M, Liu S, Huang W, Zhang J
Aging (Albany NY) 2021 Jun 11;13(11):15674-15687. doi: 10.18632/aging.203147. PMID: 34118792Free PMC Article
Optical coherence tomography impacts the evaluation of visual pathway tumors.
Banc A, Stan C, Florian IS
Neurosurg Rev 2018 Apr;41(2):415-426. Epub 2016 Jul 28 doi: 10.1007/s10143-016-0772-1. PMID: 27465394
Research progress of hydroxychloroquine and autophagy inhibitors on cancer.
Shi TT, Yu XX, Yan LJ, Xiao HT
Cancer Chemother Pharmacol 2017 Feb;79(2):287-294. Epub 2016 Nov 26 doi: 10.1007/s00280-016-3197-1. PMID: 27889812
Ocular pharmacology of topotecan and its activity in retinoblastoma.
Schaiquevich P, Carcaboso AM, Buitrago E, Taich P, Opezzo J, Bramuglia G, Chantada GL
Retina 2014 Sep;34(9):1719-27. doi: 10.1097/IAE.0000000000000253. PMID: 25099219

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