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Intracranial hemangioma

MedGen UID:
57582
•Concept ID:
C0154050
•
Neoplastic Process
Synonyms: Angioma of Intracranial Structure; angioma of intracranial structure; Angioma of the Intracranial Structure; angioma of the intracranial structure; hemangioma of brain; Hemangioma of intracranial structure; Hemangioma of Intracranial Structure; hemangioma of intracranial structure; hemangioma of intracranial structures; Hemangioma of the Intracranial Structure; hemangioma of the intracranial structure; Intracranial Angioma; intracranial angioma; Intracranial Hemangioma; intracranial hemangioma; intracranial structure hemangioma
SNOMED CT: Hemangioma of intracranial structure (93468003)
 
Monarch Initiative: MONDO:0002328

Definition

A hemangioma arising from the brain and meninges. [from NCI]

Professional guidelines

PubMed

Prenatal and postnatal diagnosis and management of congenital intracranial hemangioma.
Dermesropian F, Nassogne MC, Biard JM, Dumitriu D
Pediatr Neonatol 2021 Jul;62(4):453-455. Epub 2021 Mar 18 doi: 10.1016/j.pedneo.2021.03.008. PMID: 33865747

Recent clinical studies

Etiology

Neuroaxial Infantile Hemangiomas: Imaging Manifestations and Association with Hemangioma Syndromes.
Feygin T, Goldman-Yassen AE, Licht DJ, Schmitt JE, Mian A, Vossough A, Castelo-Soccio L, Treat JR, Bhatia A, Pollock AN
AJNR Am J Neuroradiol 2021 Aug;42(8):1520-1527. Epub 2021 Jul 8 doi: 10.3174/ajnr.A7204. PMID: 34244133Free PMC Article
Use of thalidomide to diminish growth velocity in a life-threatening congenital intracranial hemangioma.
Frei-Jones M, McKinstry RC, Perry A, Leonard JR, Park TS, Rubin JB
J Neurosurg Pediatr 2008 Aug;2(2):125-9. doi: 10.3171/PED/2008/2/8/125. PMID: 18671617Free PMC Article

Diagnosis

Durable response of intracranial cellular hemangioma to bevacizumab and temozolomide.
Yeo KK, Puscasiu E, Keating RF, Rood BR
J Neurosurg Pediatr 2013 Jun;11(6):682-6. Epub 2013 Mar 29 doi: 10.3171/2013.2.PEDS12421. PMID: 23540527
Intracranial cavernous hemangioma in a neonate.
Karmazyn B, Michovitz S, Sirota L, Drozd T, Horev G
Pediatr Radiol 2001 Sep;31(9):610-2. doi: 10.1007/s002470100488. PMID: 11511998
Recombinant alpha-interferon treatment of intracranial hemangioma and Kasabach-Merritt syndrome in an infant with cytomegalovirus.
Chiu HH, Chen RL, Lin KH, Lin DT, Lin KS
J Formos Med Assoc 1995 May;94(5):261-6. PMID: 7613260

Therapy

Intracranial hemangioma-associated cranial nerve VII palsy treated with propranolol in an infant with possible PHACE syndrome.
Zamil DH, Fernandez JK, Brown DN, Kralik SF, Herd TJ
Pediatr Dermatol 2022 Nov;39(6):950-951. Epub 2022 Oct 22 doi: 10.1111/pde.15078. PMID: 36271758
Intracranial infantile hemangioma - rare entity and common pitfalls: A comprehensive multidisciplinary approach from Neurosurgery, Neurooncology and Neuropathology.
Eibach S, Moes G, Kim J, Zovickian J, Vogel H, Pang D
Clin Neuropathol 2021 Jul-Aug;40(4):180-188. doi: 10.5414/NP301349. PMID: 33560215
Inhibition of intracranial hemangioma growth and hemorrhage by TNFSF15.
Yang GL, Han Z, Xiong J, Wang S, Wei H, Qin TT, Xiao H, Liu Y, Xu LX, Qi JW, Zhang ZS, Jiang R, Zhang J, Li LY
FASEB J 2019 Sep;33(9):10505-10514. Epub 2019 Jun 26 doi: 10.1096/fj.201802758RRR. PMID: 31242765
Durable response of intracranial cellular hemangioma to bevacizumab and temozolomide.
Yeo KK, Puscasiu E, Keating RF, Rood BR
J Neurosurg Pediatr 2013 Jun;11(6):682-6. Epub 2013 Mar 29 doi: 10.3171/2013.2.PEDS12421. PMID: 23540527
Hemifacial infantile hemangioma with intracranial extension: a rare entity.
Ersoy S, Mancini AJ
Pediatr Dermatol 2005 Jul-Aug;22(4):309-13. doi: 10.1111/j.1525-1470.2005.22405.x. PMID: 16060865

Prognosis

Inhibition of intracranial hemangioma growth and hemorrhage by TNFSF15.
Yang GL, Han Z, Xiong J, Wang S, Wei H, Qin TT, Xiao H, Liu Y, Xu LX, Qi JW, Zhang ZS, Jiang R, Zhang J, Li LY
FASEB J 2019 Sep;33(9):10505-10514. Epub 2019 Jun 26 doi: 10.1096/fj.201802758RRR. PMID: 31242765
Use of thalidomide to diminish growth velocity in a life-threatening congenital intracranial hemangioma.
Frei-Jones M, McKinstry RC, Perry A, Leonard JR, Park TS, Rubin JB
J Neurosurg Pediatr 2008 Aug;2(2):125-9. doi: 10.3171/PED/2008/2/8/125. PMID: 18671617Free PMC Article
Recombinant alpha-interferon treatment of intracranial hemangioma and Kasabach-Merritt syndrome in an infant with cytomegalovirus.
Chiu HH, Chen RL, Lin KH, Lin DT, Lin KS
J Formos Med Assoc 1995 May;94(5):261-6. PMID: 7613260

Clinical prediction guides

Use of thalidomide to diminish growth velocity in a life-threatening congenital intracranial hemangioma.
Frei-Jones M, McKinstry RC, Perry A, Leonard JR, Park TS, Rubin JB
J Neurosurg Pediatr 2008 Aug;2(2):125-9. doi: 10.3171/PED/2008/2/8/125. PMID: 18671617Free PMC Article

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