U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tubular adenocarcinoma

MedGen UID:
61428
•Concept ID:
C0205645
•
Neoplastic Process
Synonyms: Adenocarcinoma, Tubular; Adenocarcinomas, Tubular; Carcinoma, Tubular; Carcinomas, Tubular; Tubular Adenocarcinoma; Tubular Adenocarcinomas; Tubular Carcinoma; Tubular Carcinomas
SNOMED CT: Tubular adenocarcinoma (4631006); Tubular carcinoma (4631006)
 
Monarch Initiative: MONDO:0005606

Definition

An infiltrating adenocarcinoma in which the malignant cells form tubular structures. Representative examples include the tubular breast carcinoma and the gastric tubular adenocarcinoma. [from NCI]

Professional guidelines

PubMed

Clinicopathological features and lymph node metastasis risk in early gastric cancer with WHO criteria in China: 304 cases analysis.
Yang Q, Feng S, Liu H, Zhang X, Cao J, Zhu Y, Zheng H, Song H
Ann Diagn Pathol 2021 Feb;50:151652. Epub 2020 Oct 22 doi: 10.1016/j.anndiagpath.2020.151652. PMID: 33157382
Japanese Gastric Cancer Association Task Force for Research Promotion: clinical utility of ¹⁸F-fluoro-2-deoxyglucose positron emission tomography in gastric cancer. A systematic review of the literature.
Shimada H, Okazumi S, Koyama M, Murakami K
Gastric Cancer 2011 Mar;14(1):13-21. Epub 2011 Feb 18 doi: 10.1007/s10120-011-0017-5. PMID: 21331531
Effects of surgical treatment and adjuvant chemotherapy studied by the depth of penetration in gastric cancer patients undergoing curative gastrectomy.
Yasuna O, Hatayama Y, Yamaura Y, Ogiwara M, Koike H, Nakamura K, Kusano M
Surgery 1984 Jan;95(1):78-84. PMID: 6691187

Recent clinical studies

Etiology

Gastric tubular adenocarcinoma with diffuse neutrophils infiltrating: characteristics and probable treatment strategy.
Wang B, Zhu Y, Wang S, Li Z, Wang L, Rao W, Cheng N, Chen R, Ying J, Xue L
Gastric Cancer 2024 Jan;27(1):86-101. Epub 2023 Nov 29 doi: 10.1007/s10120-023-01446-6. PMID: 38019350
Endoscopic, clinicopathological, and growth characteristics of minute gastric cancer.
Liu ZH, Lu SY, Li XB, Chen HM, Chen HY, Chen XY, Fang JY, Cui Y
J Dig Dis 2022 Nov;23(11):628-635. Epub 2022 Nov 25 doi: 10.1111/1751-2980.13139. PMID: 36251460
Clinicopathological features and CT findings of papillary gastric adenocarcinoma.
Xu M, Liu S, Qiao X, Li L, Ji C, Zhou Z
Abdom Radiol (NY) 2022 Nov;47(11):3698-3711. Epub 2022 Aug 16 doi: 10.1007/s00261-022-03635-w. PMID: 35972549
Systematic review and meta-analysis of the spectrum and outcomes of different histologic subtypes of noninvasive and invasive intraductal papillary mucinous neoplasms.
Koh YX, Zheng HL, Chok AY, Tan CS, Wyone W, Lim TK, Tan DM, Goh BK
Surgery 2015 Mar;157(3):496-509. Epub 2015 Feb 3 doi: 10.1016/j.surg.2014.08.098. PMID: 25656693
Breast cancer.
Berg JW, Hutter RV
Cancer 1995 Jan 1;75(1 Suppl):257-69. doi: 10.1002/1097-0142(19950101)75:1+<257::aid-cncr2820751311>3.0.co;2-y. PMID: 8001000

Diagnosis

Gastric tubular adenocarcinoma with diffuse neutrophils infiltrating: characteristics and probable treatment strategy.
Wang B, Zhu Y, Wang S, Li Z, Wang L, Rao W, Cheng N, Chen R, Ying J, Xue L
Gastric Cancer 2024 Jan;27(1):86-101. Epub 2023 Nov 29 doi: 10.1007/s10120-023-01446-6. PMID: 38019350
Clinicopathological features and CT findings of papillary gastric adenocarcinoma.
Xu M, Liu S, Qiao X, Li L, Ji C, Zhou Z
Abdom Radiol (NY) 2022 Nov;47(11):3698-3711. Epub 2022 Aug 16 doi: 10.1007/s00261-022-03635-w. PMID: 35972549
Pancreatic Ductal Adenocarcinoma.
Dhillon J, Betancourt M
Monogr Clin Cytol 2020;26:74-91. Epub 2020 Sep 28 doi: 10.1159/000455736. PMID: 32987385
Gastric adenocarcinoma of fundic gland type with signet-ring cell carcinoma component: A case report and review of the literature.
Kai K, Satake M, Tokunaga O
World J Gastroenterol 2018 Jul 14;24(26):2915-2920. doi: 10.3748/wjg.v24.i26.2915. PMID: 30018486Free PMC Article
Histopathological diagnosis of adenocarcinoma in Barrett's esophagus.
Takubo K, Vieth M, Aida J, Matsutani T, Hagiwara N, Iwakiri K, Kumagai Y, Hongo M, Hoshihara Y, Arai T
Dig Endosc 2014 May;26(3):322-30. Epub 2013 Aug 25 doi: 10.1111/den.12160. PMID: 23981237

Therapy

Endoscopic, clinicopathological, and growth characteristics of minute gastric cancer.
Liu ZH, Lu SY, Li XB, Chen HM, Chen HY, Chen XY, Fang JY, Cui Y
J Dig Dis 2022 Nov;23(11):628-635. Epub 2022 Nov 25 doi: 10.1111/1751-2980.13139. PMID: 36251460
Brain metastasis from gallbladder neuroendocrine carcinoma.
Sasaki H, Goto T, Hirao M, Fujimoto Y
BMJ Case Rep 2020 Nov 30;13(11) doi: 10.1136/bcr-2020-238114. PMID: 33257386Free PMC Article
Evaluation of preoperative prognostic factors in patients with resectable invasive intraductal papillary mucinous carcinoma.
Izumo W, Higuchi R, Furukawa T, Yazawa T, Uemura S, Shiihara M, Yamamoto M
Surgery 2020 Dec;168(6):994-1002. Epub 2020 Mar 3 doi: 10.1016/j.surg.2020.01.014. PMID: 32139141
Resection of a Submucosal Tumor-Like Superficial Carcinoma in Middle Thoracic Esophagus Concomitant with Mucosal Adenocarcinoma and Submucosal Squamous Cell Carcinoma: A Case Report and Review of Literature.
Yamamoto S, Kumaki N, Makuuchi H, Ozawa S, Shimada H, Chino O, Kazuno A, Yasuda S, Tamayama T, Sakai I
Tokai J Exp Clin Med 2015 Sep 20;40(3):96-103. PMID: 26369262
Radiation therapy for advanced gastric cancer.
Tsukiyama I, Akine Y, Kajiura Y, Ogino T, Yamashita K, Egawa S, Hijikata J, Kitagawa T
Int J Radiat Oncol Biol Phys 1988 Jul;15(1):123-7. doi: 10.1016/0360-3016(88)90355-0. PMID: 2839438

Prognosis

Gastric tubular adenocarcinoma with diffuse neutrophils infiltrating: characteristics and probable treatment strategy.
Wang B, Zhu Y, Wang S, Li Z, Wang L, Rao W, Cheng N, Chen R, Ying J, Xue L
Gastric Cancer 2024 Jan;27(1):86-101. Epub 2023 Nov 29 doi: 10.1007/s10120-023-01446-6. PMID: 38019350
Brain metastasis from gallbladder neuroendocrine carcinoma.
Sasaki H, Goto T, Hirao M, Fujimoto Y
BMJ Case Rep 2020 Nov 30;13(11) doi: 10.1136/bcr-2020-238114. PMID: 33257386Free PMC Article
Colonic clear cell adenocarcinoma with enteroblastic differentiation.
Shiratori Y, Suzuki K, Ikeya T
Clin J Gastroenterol 2020 Dec;13(6):1196-1199. Epub 2020 Aug 17 doi: 10.1007/s12328-020-01209-1. PMID: 32803644
Systematic review and meta-analysis of the spectrum and outcomes of different histologic subtypes of noninvasive and invasive intraductal papillary mucinous neoplasms.
Koh YX, Zheng HL, Chok AY, Tan CS, Wyone W, Lim TK, Tan DM, Goh BK
Surgery 2015 Mar;157(3):496-509. Epub 2015 Feb 3 doi: 10.1016/j.surg.2014.08.098. PMID: 25656693
Breast cancer.
Berg JW, Hutter RV
Cancer 1995 Jan 1;75(1 Suppl):257-69. doi: 10.1002/1097-0142(19950101)75:1+<257::aid-cncr2820751311>3.0.co;2-y. PMID: 8001000

Clinical prediction guides

Clinicopathological and molecular characteristics of gastric papillary adenocarcinoma.
Arai T, Komatsu A, Kanazawa N, Nonaka K, Ishiwata T
Pathol Int 2023 Aug;73(8):358-366. Epub 2023 Jun 21 doi: 10.1111/pin.13345. PMID: 37341602
Combined tubular adenocarcinoma, neuroendocrine carcinoma and adenocarcinoma with enteroblastic differentiation arising in Barrett esophagus.
Sugawara K, Fukuda T, Kishimoto Y, Oka D, Kawashima Y, Inoshita N, Kanda H
Clin J Gastroenterol 2023 Aug;16(4):501-507. Epub 2023 Apr 7 doi: 10.1007/s12328-023-01791-0. PMID: 37027114Free PMC Article
Endoscopic, clinicopathological, and growth characteristics of minute gastric cancer.
Liu ZH, Lu SY, Li XB, Chen HM, Chen HY, Chen XY, Fang JY, Cui Y
J Dig Dis 2022 Nov;23(11):628-635. Epub 2022 Nov 25 doi: 10.1111/1751-2980.13139. PMID: 36251460
Solitary pleural metastasis in rectal cancer.
Mizushima H, Sakimura Y, Nishimura A, Tawara H, Hayashi K, Kato K, Tsuji T, Yamamoto D, Kitamura H, Kadoya S, Bando H, Kurumaya H, Minato H
Clin J Gastroenterol 2022 Feb;15(1):164-170. Epub 2022 Jan 6 doi: 10.1007/s12328-021-01565-6. PMID: 34988881
Gastric adenocarcinoma of fundic gland type with signet-ring cell carcinoma component: A case report and review of the literature.
Kai K, Satake M, Tokunaga O
World J Gastroenterol 2018 Jul 14;24(26):2915-2920. doi: 10.3748/wjg.v24.i26.2915. PMID: 30018486Free PMC Article

Recent systematic reviews

Systematic review and meta-analysis of the spectrum and outcomes of different histologic subtypes of noninvasive and invasive intraductal papillary mucinous neoplasms.
Koh YX, Zheng HL, Chok AY, Tan CS, Wyone W, Lim TK, Tan DM, Goh BK
Surgery 2015 Mar;157(3):496-509. Epub 2015 Feb 3 doi: 10.1016/j.surg.2014.08.098. PMID: 25656693
Japanese Gastric Cancer Association Task Force for Research Promotion: clinical utility of ¹⁸F-fluoro-2-deoxyglucose positron emission tomography in gastric cancer. A systematic review of the literature.
Shimada H, Okazumi S, Koyama M, Murakami K
Gastric Cancer 2011 Mar;14(1):13-21. Epub 2011 Feb 18 doi: 10.1007/s10120-011-0017-5. PMID: 21331531

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...