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Chondromyxoid fibroma

MedGen UID:
66375
Concept ID:
C0221290
Neoplastic Process
Synonyms: Chondromyxoid Fibroma; chondromyxoid fibroma; CMF - Chondromyxoid fibroma
SNOMED CT: CMF - Chondromyxoid fibroma (39553005); Chondromyxoid fibroma (39553005)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0018447
Orphanet: ORPHA404507

Definition

A rare bone tumor characterized by a benign lesion composed of lobules of spindle shaped or stellate cells and an abundant myxoid or chondroid matrix. The tumor may occur in almost any osseous location but is most common in long bones, in particular the proximal tibia and the distal femur. Pain is the most common presenting symptom. Prognosis is excellent even in cases with local recurrence. [from ORDO]

Term Hierarchy

Professional guidelines

PubMed

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Recent clinical studies

Etiology

De La Peña NM, Yekzaman BR, Patra DP, Rath TJ, Lal D, Bendok BR
World Neurosurg 2022 Jun;162:21-28. Epub 2021 Oct 25 doi: 10.1016/j.wneu.2021.10.139. PMID: 34710582
Zhong J, Si L, Geng J, Xing Y, Hu Y, Jiao Q, Zhang H, Yao W
BMC Musculoskelet Disord 2020 Jan 29;21(1):53. doi: 10.1186/s12891-020-3063-5. PMID: 31996205Free PMC Article
Kwee TC, de Klerk JMH, Nix M, Heggelman BGF, Dubois SV, Adams HJA
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Int J Pediatr Otorhinolaryngol 2013 Jun;77(6):964-71. Epub 2013 Apr 6 doi: 10.1016/j.ijporl.2013.03.018. PMID: 23571019

Diagnosis

Zhong J, Si L, Geng J, Xing Y, Hu Y, Jiao Q, Zhang H, Yao W
BMC Musculoskelet Disord 2020 Jan 29;21(1):53. doi: 10.1186/s12891-020-3063-5. PMID: 31996205Free PMC Article
Qasem SA, DeYoung BR
Semin Diagn Pathol 2014 Jan;31(1):10-20. Epub 2014 Jan 23 doi: 10.1053/j.semdp.2014.01.006. PMID: 24680178
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Therapy

Karaca MO, Özyıldıran M, Alizade R, Başarır K, Yıldız HY
Jt Dis Relat Surg 2024 Apr 26;35(2):377-385. doi: 10.52312/jdrs.2024.1620. PMID: 38727118Free PMC Article
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Prognosis

Dodson V, Majmundar N, Sharer L, Fitzhugh VA, Assina R
Int J Surg Pathol 2020 Oct;28(7):799-803. Epub 2020 May 4 doi: 10.1177/1066896920916784. PMID: 32362154
Zhong J, Si L, Geng J, Xing Y, Hu Y, Jiao Q, Zhang H, Yao W
BMC Musculoskelet Disord 2020 Jan 29;21(1):53. doi: 10.1186/s12891-020-3063-5. PMID: 31996205Free PMC Article
Kilic D, Findikcioglu A, Tepeoglu M, Vural C
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Cherekaev VA, Golbin DA, Gasparyan TG, Shishkina LV, Tsukanova TV
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Clinical prediction guides

Toland AMS, Lam SW, Varma S, Wang A, Howitt BE, Kunder CA, Kerr DA, Szuhai K, Bovée JVMG, Charville GW
Am J Surg Pathol 2022 Oct 1;46(10):1407-1414. Epub 2022 Jun 1 doi: 10.1097/PAS.0000000000001921. PMID: 35650682Free PMC Article
Liu T, Yao J, Li X, Qi X, Zhao P, Tan Z, Wang J, Li Y
Medicine (Baltimore) 2020 Mar;99(11):e19487. doi: 10.1097/MD.0000000000019487. PMID: 32176085Free PMC Article
Jamshidi K, Najd Mazhar F, Jafari D
Arch Iran Med 2015 Jun;18(6):367-70. PMID: 26058932
Cherekaev VA, Golbin DA, Gasparyan TG, Shishkina LV, Tsukanova TV
J Craniofac Surg 2015 Jan;26(1):10-8. doi: 10.1097/SCS.0000000000001307. PMID: 25569383
Kim HS, Jee WH, Ryu KN, Cho KH, Suh JS, Cho JH, Choi YS, Lee SM, Lee JM, Sung MS, Kim JY, Jung ES, Chung YG, Ok IY
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Recent systematic reviews

De La Peña NM, Yekzaman BR, Patra DP, Rath TJ, Lal D, Bendok BR
World Neurosurg 2022 Jun;162:21-28. Epub 2021 Oct 25 doi: 10.1016/j.wneu.2021.10.139. PMID: 34710582

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