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Metastatic Malignant Neoplasm in the Lacrimal Gland

MedGen UID:
673340
•Concept ID:
C0686483
•
Neoplastic Process
Synonyms: Metastatic malignant neoplasm of lacrimal gland; Metastatic malignant neoplasm to lacrimal gland; Secondary malignant neoplasm of lacrimal gland
SNOMED CT: Secondary malignant neoplasm of lacrimal gland (94364006); Metastatic malignant neoplasm to lacrimal gland (94364006); Metastatic malignant neoplasm of lacrimal gland (94364006)

Definition

A malignant neoplasm that has spread from its original site of growth to the lacrimal gland. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Neoplasm in the Lacrimal Gland

Professional guidelines

PubMed

Current treatment of lacrimal gland carcinoma.
Woo KI, Kim YD, Sa HS, Esmaeli B
Curr Opin Ophthalmol 2016 Sep;27(5):449-56. doi: 10.1097/ICU.0000000000000301. PMID: 27273588
Management of Lacrimal Gland Carcinoma: Lessons From the Literature in the Past 40 Years.
Woo KI, Yeom A, Esmaeli B
Ophthalmic Plast Reconstr Surg 2016 Jan-Feb;32(1):1-10. doi: 10.1097/IOP.0000000000000531. PMID: 26291539
Management of excessive tearing as a side effect of docetaxel.
Esmaeli B
Clin Breast Cancer 2005 Feb;5(6):455-7. doi: 10.3816/cbc.2005.n.004. PMID: 15748466

Recent clinical studies

Etiology

Overview of benign and malignant lacrimal gland tumors.
Gündüz AK, Yeşiltaş YS, Shields CL
Curr Opin Ophthalmol 2018 Sep;29(5):458-468. doi: 10.1097/ICU.0000000000000515. PMID: 30028745
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
Epiphora after radioactive iodine therapy in a low-risk patient.
Song H, Jeong J, Ju Koh M
Clin Nucl Med 2015 Jun;40(6):536-7. doi: 10.1097/RLU.0000000000000717. PMID: 25674875
Intranasal mucocele of the nasolacrimal duct: an important cause of neonatal nasal obstruction.
Brachlow A, Schwartz RH, Bahadori RS
Clin Pediatr (Phila) 2004 Jun;43(5):479-81. doi: 10.1177/000992280404300511. PMID: 15208755
Nasal obstruction in the neonate secondary to nasolacrimal duct cysts.
Paoli C, François M, Triglia JM, Frydman E, Polonovski JM, Narcy P
Laryngoscope 1995 Jan;105(1):86-9. doi: 10.1288/00005537-199501000-00019. PMID: 7837921

Diagnosis

Large Dacryops Mimicking Lacrimal Gland Tumor With Secondary Corneal Ulcer.
Pornseth A, Charukamnoetkanok P, Uiprasertkul M, Sintuwong S
Ophthalmic Plast Reconstr Surg 2021 May-Jun 01;37(3S):S167. doi: 10.1097/IOP.0000000000001735. PMID: 32732534
Enigma portal section: Lymph node fine-needle aspiration.
Furtado L, Futata P, Zanella D, Saieg M
Cytopathology 2020 Nov;31(6):619-621. Epub 2020 Jul 13 doi: 10.1111/cyt.12869. PMID: 32485065
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
Glial heterotopia or ectopic brain masquerading as a dacyrocystocele.
Ali MJ, Kamal S, Vemuganti GK, Naik MN
Ophthalmic Plast Reconstr Surg 2015 Mar-Apr;31(2):e26-8. doi: 10.1097/IOP.0000000000000050. PMID: 24492734
Plasmacytoma associated with canaliculitis.
You JY, Glassman ML, McCormick SA, Milman T
Ophthalmic Plast Reconstr Surg 2012 May-Jun;28(3):e60-2. doi: 10.1097/IOP.0b013e3182238b75. PMID: 21743365

Therapy

Metastatic HER2 lacrimal/salivary gland duct adenocarcinoma.
Mansi RA, Morris B, Fulcher T, McDermott JH
BMJ Case Rep 2023 Jun 30;16(6) doi: 10.1136/bcr-2022-253928. PMID: 37399351Free PMC Article
Epiphora after radioactive iodine therapy in a low-risk patient.
Song H, Jeong J, Ju Koh M
Clin Nucl Med 2015 Jun;40(6):536-7. doi: 10.1097/RLU.0000000000000717. PMID: 25674875
Dacryocystography with nasolacrimal probing under fluoroscopic guidance for treatment of congenital dacryocystocele.
Narioka J, Ohashi Y
J AAPOS 2008 Jun;12(3):299-301. Epub 2008 Mar 24 doi: 10.1016/j.jaapos.2008.01.001. PMID: 18359654
Upper and lower system nasolacrimal duct stenosis secondary to paclitaxel.
McCartney E, Valluri S, Rushing D, Burgett R
Ophthalmic Plast Reconstr Surg 2007 Mar-Apr;23(2):170-1. doi: 10.1097/IOP.0b013e318032e908. PMID: 17413646
Management of excessive tearing as a side effect of docetaxel.
Esmaeli B
Clin Breast Cancer 2005 Feb;5(6):455-7. doi: 10.3816/cbc.2005.n.004. PMID: 15748466

Prognosis

Overview of benign and malignant lacrimal gland tumors.
Gündüz AK, Yeşiltaş YS, Shields CL
Curr Opin Ophthalmol 2018 Sep;29(5):458-468. doi: 10.1097/ICU.0000000000000515. PMID: 30028745
Lacrimal Sac Tumors--A Review.
Krishna Y, Coupland SE
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):173-178. doi: 10.22608/APO.201713. PMID: 28399337
Nasolacrimal duct obstruction secondary to dermatofibrosarcoma protuberans.
Bryar P, Sun R, Ebroon D
Ophthalmology 2004 Jul;111(7):1398-400. doi: 10.1016/j.ophtha.2003.12.048. PMID: 15234144
Nasal obstruction in the neonate secondary to nasolacrimal duct cysts.
Paoli C, François M, Triglia JM, Frydman E, Polonovski JM, Narcy P
Laryngoscope 1995 Jan;105(1):86-9. doi: 10.1288/00005537-199501000-00019. PMID: 7837921
Role of the radiotherapist in orbital disease.
Henk JM
Trans Ophthalmol Soc U K (1962) 1979 Jul;99(2):234-5. PMID: 298417

Clinical prediction guides

Topographic and anatomical features of the nasolacrimal duct obstruction due to radioiodine treatment.
Yartsev VD, Atkova EL, Ekaterinchev MA
Int Ophthalmol 2023 Sep;43(9):3385-3390. Epub 2023 May 18 doi: 10.1007/s10792-023-02746-7. PMID: 37199817
Dacryops and clinical diagnostic challenges.
Alsarhani WK, Al-Sharif EM, Al-Faky YH, Alkatan HM, Maktabi AM, Alsuhaibani AH
Can J Ophthalmol 2022 Dec;57(6):388-393. Epub 2021 Jul 26 doi: 10.1016/j.jcjo.2021.06.014. PMID: 34324876
Lymphoma of the Lacrimal Gland - An International Multicenter Retrospective Study.
Vest SD, Mikkelsen LH, Holm F, Rasmussen PK, Hindso TG, Knudsen MKH, Coupland SE, Esmaeli B, Finger PT, Graue GF, Grossniklaus HE, Honavar SG, Mulay K, Sjö LD, Sniegowski MC, Vemuganti GK, Thuro BA, Heegaard S
Am J Ophthalmol 2020 Nov;219:107-120. Epub 2020 Jun 20 doi: 10.1016/j.ajo.2020.06.015. PMID: 32574779
The validity of the Mirels score for predicting impending pathological fractures of the lower limb.
Howard EL, Shepherd KL, Cribb G, Cool P
Bone Joint J 2018 Aug;100-B(8):1100-1105. doi: 10.1302/0301-620X.100B8.BJJ-2018-0300.R1. PMID: 30062934
Autoimmune Granulomatous Inflammation of Lacrimal Glands and Axonal Neuritis Following Treatment With Ipilimumab and Radiation Therapy.
Ileana Dumbrava E, Smith V, Alfattal R, El-Naggar AK, Penas-Prado M, Tsimberidou AM
J Immunother 2018 Sep;41(7):336-339. doi: 10.1097/CJI.0000000000000224. PMID: 29787423Free PMC Article

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