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Bloodstream infectious agent

MedGen UID:
748422
Concept ID:
C2317548
Finding
Synonym: Infectious agent in bloodstream
SNOMED CT: Infectious agent in bloodstream (434156008)
 
HPO: HP:0031863

Definition

The presence of an infectious agent in the blood circulation. [from HPO]

Professional guidelines

PubMed

Evans L, Rhodes A, Alhazzani W, Antonelli M, Coopersmith CM, French C, Machado FR, Mcintyre L, Ostermann M, Prescott HC, Schorr C, Simpson S, Wiersinga WJ, Alshamsi F, Angus DC, Arabi Y, Azevedo L, Beale R, Beilman G, Belley-Cote E, Burry L, Cecconi M, Centofanti J, Coz Yataco A, De Waele J, Dellinger RP, Doi K, Du B, Estenssoro E, Ferrer R, Gomersall C, Hodgson C, Hylander Møller M, Iwashyna T, Jacob S, Kleinpell R, Klompas M, Koh Y, Kumar A, Kwizera A, Lobo S, Masur H, McGloughlin S, Mehta S, Mehta Y, Mer M, Nunnally M, Oczkowski S, Osborn T, Papathanassoglou E, Perner A, Puskarich M, Roberts J, Schweickert W, Seckel M, Sevransky J, Sprung CL, Welte T, Zimmerman J, Levy M
Crit Care Med 2021 Nov 1;49(11):e1063-e1143. doi: 10.1097/CCM.0000000000005337. PMID: 34605781
Miller JM, Binnicker MJ, Campbell S, Carroll KC, Chapin KC, Gilligan PH, Gonzalez MD, Jerris RC, Kehl SC, Patel R, Pritt BS, Richter SS, Robinson-Dunn B, Schwartzman JD, Snyder JW, Telford S 3rd, Theel ES, Thomson RB Jr, Weinstein MP, Yao JD
Clin Infect Dis 2018 Aug 31;67(6):e1-e94. doi: 10.1093/cid/ciy381. PMID: 29955859Free PMC Article
Chaves F, Garnacho-Montero J, Del Pozo JL, Bouza E, Capdevila JA, de Cueto M, Domínguez MÁ, Esteban J, Fernández-Hidalgo N, Fernández Sampedro M, Fortún J, Guembe M, Lorente L, Paño JR, Ramírez P, Salavert M, Sánchez M, Vallés J
Med Intensiva (Engl Ed) 2018 Jan-Feb;42(1):5-36. doi: 10.1016/j.medin.2017.09.012. PMID: 29406956

Recent clinical studies

Etiology

McCarty TP, White CM, Pappas PG
Infect Dis Clin North Am 2021 Jun;35(2):389-413. doi: 10.1016/j.idc.2021.03.007. PMID: 34016283
Kern WV, Rieg S
Clin Microbiol Infect 2020 Feb;26(2):151-157. Epub 2019 Nov 9 doi: 10.1016/j.cmi.2019.10.031. PMID: 31712069
Kumbar L, Yee J
Adv Chronic Kidney Dis 2019 Jan;26(1):16-22. doi: 10.1053/j.ackd.2018.10.005. PMID: 30876612
Restrepo A, Clark NM; Infectious Diseases Community of Practice of the American Society of Transplantation
Clin Transplant 2019 Sep;33(9):e13509. Epub 2019 Mar 19 doi: 10.1111/ctr.13509. PMID: 30817024
Miller JM, Binnicker MJ, Campbell S, Carroll KC, Chapin KC, Gilligan PH, Gonzalez MD, Jerris RC, Kehl SC, Patel R, Pritt BS, Richter SS, Robinson-Dunn B, Schwartzman JD, Snyder JW, Telford S 3rd, Theel ES, Thomson RB Jr, Weinstein MP, Yao JD
Clin Infect Dis 2018 Aug 31;67(6):e1-e94. doi: 10.1093/cid/ciy381. PMID: 29955859Free PMC Article

Diagnosis

Czeresnia JM, Weiss LM
Lung 2022 Apr;200(2):141-148. Epub 2022 Apr 9 doi: 10.1007/s00408-022-00528-z. PMID: 35396957Free PMC Article
Peri AM, Harris PNA, Paterson DL
Clin Microbiol Infect 2022 Feb;28(2):195-201. Epub 2021 Oct 20 doi: 10.1016/j.cmi.2021.09.039. PMID: 34687856
McCarty TP, White CM, Pappas PG
Infect Dis Clin North Am 2021 Jun;35(2):389-413. doi: 10.1016/j.idc.2021.03.007. PMID: 34016283
Miller JM, Binnicker MJ, Campbell S, Carroll KC, Chapin KC, Gilligan PH, Gonzalez MD, Jerris RC, Kehl SC, Patel R, Pritt BS, Richter SS, Robinson-Dunn B, Schwartzman JD, Snyder JW, Telford S 3rd, Theel ES, Thomson RB Jr, Weinstein MP, Yao JD
Clin Infect Dis 2018 Aug 31;67(6):e1-e94. doi: 10.1093/cid/ciy381. PMID: 29955859Free PMC Article
Chaves F, Garnacho-Montero J, Del Pozo JL, Bouza E, Capdevila JA, de Cueto M, Domínguez MÁ, Esteban J, Fernández-Hidalgo N, Fernández Sampedro M, Fortún J, Guembe M, Lorente L, Paño JR, Ramírez P, Salavert M, Sánchez M, Vallés J
Med Intensiva (Engl Ed) 2018 Jan-Feb;42(1):5-36. doi: 10.1016/j.medin.2017.09.012. PMID: 29406956

Therapy

Kaye KS, Shorr AF, Wunderink RG, Du B, Poirier GE, Rana K, Miller A, Lewis D, O'Donnell J, Chen L, Reinhart H, Srinivasan S, Isaacs R, Altarac D
Lancet Infect Dis 2023 Sep;23(9):1072-1084. Epub 2023 May 11 doi: 10.1016/S1473-3099(23)00184-6. PMID: 37182534
Kern WV, Rieg S
Clin Microbiol Infect 2020 Feb;26(2):151-157. Epub 2019 Nov 9 doi: 10.1016/j.cmi.2019.10.031. PMID: 31712069
Bassetti M, Giacobbe DR, Vena A, Wolff M
Semin Respir Crit Care Med 2019 Aug;40(4):524-539. Epub 2019 Oct 4 doi: 10.1055/s-0039-1693704. PMID: 31585478
Harris PNA, Tambyah PA, Lye DC, Mo Y, Lee TH, Yilmaz M, Alenazi TH, Arabi Y, Falcone M, Bassetti M, Righi E, Rogers BA, Kanj S, Bhally H, Iredell J, Mendelson M, Boyles TH, Looke D, Miyakis S, Walls G, Al Khamis M, Zikri A, Crowe A, Ingram P, Daneman N, Griffin P, Athan E, Lorenc P, Baker P, Roberts L, Beatson SA, Peleg AY, Harris-Brown T, Paterson DL; MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN)
JAMA 2018 Sep 11;320(10):984-994. doi: 10.1001/jama.2018.12163. PMID: 30208454Free PMC Article
Beganovic M, Luther MK, Rice LB, Arias CA, Rybak MJ, LaPlante KL
Clin Infect Dis 2018 Jul 2;67(2):303-309. doi: 10.1093/cid/ciy064. PMID: 29390132Free PMC Article

Prognosis

Kern WV, Rieg S
Clin Microbiol Infect 2020 Feb;26(2):151-157. Epub 2019 Nov 9 doi: 10.1016/j.cmi.2019.10.031. PMID: 31712069
Tamma PD, Conley AT, Cosgrove SE, Harris AD, Lautenbach E, Amoah J, Avdic E, Tolomeo P, Wise J, Subudhi S, Han JH; Antibacterial Resistance Leadership Group
JAMA Intern Med 2019 Mar 1;179(3):316-323. doi: 10.1001/jamainternmed.2018.6226. PMID: 30667477Free PMC Article
Pallotto C, Fiorio M, De Angelis V, Ripoli A, Franciosini E, Quondam Girolamo L, Volpi F, Iorio P, Francisci D, Tascini C, Baldelli F
Clin Microbiol Infect 2019 Jun;25(6):705-710. Epub 2018 Sep 26 doi: 10.1016/j.cmi.2018.09.012. PMID: 30267930
Harris PNA, Tambyah PA, Lye DC, Mo Y, Lee TH, Yilmaz M, Alenazi TH, Arabi Y, Falcone M, Bassetti M, Righi E, Rogers BA, Kanj S, Bhally H, Iredell J, Mendelson M, Boyles TH, Looke D, Miyakis S, Walls G, Al Khamis M, Zikri A, Crowe A, Ingram P, Daneman N, Griffin P, Athan E, Lorenc P, Baker P, Roberts L, Beatson SA, Peleg AY, Harris-Brown T, Paterson DL; MERINO Trial Investigators and the Australasian Society for Infectious Disease Clinical Research Network (ASID-CRN)
JAMA 2018 Sep 11;320(10):984-994. doi: 10.1001/jama.2018.12163. PMID: 30208454Free PMC Article
Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent JL, Angus DC
JAMA 2016 Feb 23;315(8):801-10. doi: 10.1001/jama.2016.0287. PMID: 26903338Free PMC Article

Clinical prediction guides

Cairns KA, Udy AA, Peel TN, Abbott IJ, Dooley MJ, Peleg AY
Clin Microbiol Rev 2023 Jun 21;36(2):e0005922. Epub 2023 Apr 17 doi: 10.1128/cmr.00059-22. PMID: 37067406Free PMC Article
Reyes J, Komarow L, Chen L, Ge L, Hanson BM, Cober E, Herc E, Alenazi T, Kaye KS, Garcia-Diaz J, Li L, Kanj SS, Liu Z, Oñate JM, Salata RA, Marimuthu K, Gao H, Zong Z, Valderrama-Beltrán SL, Yu Y, Tambyah P, Weston G, Salcedo S, Abbo LM, Xie Q, Ordoñez K, Wang M, Stryjewski ME, Munita JM, Paterson DL, Evans S, Hill C, Baum K, Bonomo RA, Kreiswirth BN, Villegas MV, Patel R, Arias CA, Chambers HF, Fowler VG Jr, Doi Y, van Duin D, Satlin MJ; Antibacterial Resistance Leadership Group and Multi-Drug Resistant Organism Network Investigators
Lancet Microbe 2023 Mar;4(3):e159-e170. Epub 2023 Feb 9 doi: 10.1016/S2666-5247(22)00329-9. PMID: 36774938Free PMC Article
Timsit JF, Ruppé E, Barbier F, Tabah A, Bassetti M
Intensive Care Med 2020 Feb;46(2):266-284. Epub 2020 Feb 11 doi: 10.1007/s00134-020-05950-6. PMID: 32047941Free PMC Article
Tamma PD, Conley AT, Cosgrove SE, Harris AD, Lautenbach E, Amoah J, Avdic E, Tolomeo P, Wise J, Subudhi S, Han JH; Antibacterial Resistance Leadership Group
JAMA Intern Med 2019 Mar 1;179(3):316-323. doi: 10.1001/jamainternmed.2018.6226. PMID: 30667477Free PMC Article
Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent JL, Angus DC
JAMA 2016 Feb 23;315(8):801-10. doi: 10.1001/jama.2016.0287. PMID: 26903338Free PMC Article

Recent systematic reviews

Bai AD, Lo CKL, Komorowski AS, Suresh M, Guo K, Garg A, Tandon P, Senecal J, Del Corpo O, Stefanova I, Fogarty C, Butler-Laporte G, McDonald EG, Cheng MP, Morris AM, Loeb M, Lee TC
Clin Microbiol Infect 2022 Aug;28(8):1076-1084. Epub 2022 Mar 23 doi: 10.1016/j.cmi.2022.03.015. PMID: 35339678
Zha L, Pan L, Guo J, French N, Villanueva EV, Tefsen B
Adv Ther 2020 Mar;37(3):1049-1064. Epub 2020 Jan 31 doi: 10.1007/s12325-020-01235-y. PMID: 32006240Free PMC Article
Sheng KX, Zhang P, Li JW, Cheng J, He YC, Böhlke M, Chen JH
Clin Microbiol Infect 2020 May;26(5):545-552. Epub 2019 Dec 16 doi: 10.1016/j.cmi.2019.12.003. PMID: 31857208
Musuuza JS, Guru PK, O'Horo JC, Bongiorno CM, Korobkin MA, Gangnon RE, Safdar N
BMC Infect Dis 2019 May 14;19(1):416. doi: 10.1186/s12879-019-4002-7. PMID: 31088521Free PMC Article
Timbrook TT, Morton JB, McConeghy KW, Caffrey AR, Mylonakis E, LaPlante KL
Clin Infect Dis 2017 Jan 1;64(1):15-23. Epub 2016 Sep 26 doi: 10.1093/cid/ciw649. PMID: 27678085

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