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Ampulla of Vater Pancreatobiliary Type Adenocarcinoma

MedGen UID:
758634
Concept ID:
C3472607
Neoplastic Process
Synonyms: Adenocarcinoma, pancreatobiliary-type; Pancreatobiliary-type carcinoma
SNOMED CT: Pancreatobiliary-type carcinoma (450894009); Adenocarcinoma, pancreatobiliary-type (450894009)

Definition

An invasive adenocarcinoma that arises from the ampulla of Vater. It is characterized by the presence of malignant cells that resemble the malignant cells of the pancreatic ductal or extrahepatic bile duct carcinomas. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmpulla of Vater Pancreatobiliary Type Adenocarcinoma

Professional guidelines

PubMed

Patel M, Uboha NV
Curr Treat Options Oncol 2021 Sep 29;22(11):103. doi: 10.1007/s11864-021-00894-5. PMID: 34586537

Recent clinical studies

Etiology

Kwon CH, Ahn JH, Seo HI, Kim DU, Han SY, Kim S, Lee NK, Hong SB, Park YM, Noh BG
World J Surg Oncol 2024 Jan 3;22(1):5. doi: 10.1186/s12957-023-03289-y. PMID: 38167037Free PMC Article
Krishnamurthy K, Sriganeshan V
Pathol Oncol Res 2020 Jul;26(3):1735-1739. Epub 2019 Oct 22 doi: 10.1007/s12253-019-00754-6. PMID: 31642034
da Silveira Santos JPL, Machado CJ, Junior EP, Rodrigues JBSR, Vidigal PT, Resende V
J Gastrointest Surg 2018 Jul;22(7):1171-1178. Epub 2018 May 7 doi: 10.1007/s11605-018-3797-7. PMID: 29736668
Westgaard A, Pomianowska E, Clausen OP, Gladhaug IP
Ann Surg Oncol 2013 Feb;20(2):430-9. Epub 2012 Sep 7 doi: 10.1245/s10434-012-2603-0. PMID: 22956064
Heinrich S, Clavien PA
Curr Opin Gastroenterol 2010 May;26(3):280-5. doi: 10.1097/MOG.0b013e3283378eb0. PMID: 20168227

Diagnosis

Patel M, Uboha NV
Curr Treat Options Oncol 2021 Sep 29;22(11):103. doi: 10.1007/s11864-021-00894-5. PMID: 34586537
da Silveira Santos JPL, Machado CJ, Junior EP, Rodrigues JBSR, Vidigal PT, Resende V
J Gastrointest Surg 2018 Jul;22(7):1171-1178. Epub 2018 May 7 doi: 10.1007/s11605-018-3797-7. PMID: 29736668
Asano E, Okano K, Oshima M, Kagawa S, Kushida Y, Munekage M, Hanazaki K, Watanabe J, Takada Y, Ikemoto T, Shimada M, Suzuki Y; Shikoku Consortium of Surgical Research (SCSR)
J Surg Oncol 2016 Jul;114(1):119-27. Epub 2016 May 2 doi: 10.1002/jso.24274. PMID: 27132476
Kumari N, Prabha K, Singh RK, Baitha DK, Krishnani N
Hum Pathol 2013 Oct;44(10):2213-9. Epub 2013 Jul 5 doi: 10.1016/j.humpath.2013.05.003. PMID: 23834763
Schultz NA, Werner J, Willenbrock H, Roslind A, Giese N, Horn T, Wøjdemann M, Johansen JS
Mod Pathol 2012 Dec;25(12):1609-22. Epub 2012 Aug 10 doi: 10.1038/modpathol.2012.122. PMID: 22878649

Therapy

Uijterwijk BA, Lemmers DH, Ghidini M, Wilmink JW, Zaniboni A, Fusai GK, Zerbi A, Koerkamp BG, Luyer M, Ghorbani P, Salvia R, White S, Ielpo B, Goh BKP, Boggi U, Kazemier G, House MG, Mavroeidis VK, Björnsson B, Mazzola M, Serradilla M, Korkolis D, Alseidi A, Roberts KJ, Soonawalla Z, Pessaux P, Fisher WE, Koek S, Kent TS, Vladimirov M, Bolm L, Jamieson N, Dalla Valle R, Kleeff J, Mazzotta A, Suarez Muñoz MA, Cabús SS, Ball CG, Berger AC, Ferarri C, Besselink MG, Hilal MA; International Study Group on non-pancreatic periampullary Cancer (ISGACA)
Br J Cancer 2024 Jul;131(1):117-125. Epub 2024 May 28 doi: 10.1038/s41416-024-02692-w. PMID: 38806725Free PMC Article
Patel M, Uboha NV
Curr Treat Options Oncol 2021 Sep 29;22(11):103. doi: 10.1007/s11864-021-00894-5. PMID: 34586537
Elebro J, Ben Dror L, Heby M, Nodin B, Jirström K, Eberhard J
Acta Oncol 2016;55(3):286-96. Epub 2015 Sep 11 doi: 10.3109/0284186X.2015.1075663. PMID: 26362587Free PMC Article
Kim HS, Shin SJ, Kim JH, Kim H, Choi HJ
Tohoku J Exp Med 2013 Sep;231(1):21-8. doi: 10.1620/tjem.231.21. PMID: 23994910
Heinrich S, Clavien PA
Curr Opin Gastroenterol 2010 May;26(3):280-5. doi: 10.1097/MOG.0b013e3283378eb0. PMID: 20168227

Prognosis

Cheng J, Mao Y, Hong W, Hu W, Shu P, Huang K, Yu J, Jiang M, Li L, Wang W, Ni D, Li S
J Transl Med 2022 Jun 15;20(1):272. doi: 10.1186/s12967-022-03473-w. PMID: 35705951Free PMC Article
Patel M, Uboha NV
Curr Treat Options Oncol 2021 Sep 29;22(11):103. doi: 10.1007/s11864-021-00894-5. PMID: 34586537
da Silveira Santos JPL, Machado CJ, Junior EP, Rodrigues JBSR, Vidigal PT, Resende V
J Gastrointest Surg 2018 Jul;22(7):1171-1178. Epub 2018 May 7 doi: 10.1007/s11605-018-3797-7. PMID: 29736668
Perysinakis I, Margaris I, Kouraklis G
Histopathology 2014 May;64(6):759-68. Epub 2014 Jan 24 doi: 10.1111/his.12324. PMID: 24456259
Heinrich S, Clavien PA
Curr Opin Gastroenterol 2010 May;26(3):280-5. doi: 10.1097/MOG.0b013e3283378eb0. PMID: 20168227

Clinical prediction guides

Kwon CH, Ahn JH, Seo HI, Kim DU, Han SY, Kim S, Lee NK, Hong SB, Park YM, Noh BG
World J Surg Oncol 2024 Jan 3;22(1):5. doi: 10.1186/s12957-023-03289-y. PMID: 38167037Free PMC Article
Krishnamurthy K, Sriganeshan V
Pathol Oncol Res 2020 Jul;26(3):1735-1739. Epub 2019 Oct 22 doi: 10.1007/s12253-019-00754-6. PMID: 31642034
da Silveira Santos JPL, Machado CJ, Junior EP, Rodrigues JBSR, Vidigal PT, Resende V
J Gastrointest Surg 2018 Jul;22(7):1171-1178. Epub 2018 May 7 doi: 10.1007/s11605-018-3797-7. PMID: 29736668
Perysinakis I, Minaidou E, Mantas D, Sotiropoulos GC, Leontara V, Tsipras H, Zografos GN, Margaris I, Kouraklis G
Pathol Res Pract 2016 Nov;212(11):1039-1047. Epub 2016 Sep 22 doi: 10.1016/j.prp.2016.09.004. PMID: 27688085
Schultz NA, Werner J, Willenbrock H, Roslind A, Giese N, Horn T, Wøjdemann M, Johansen JS
Mod Pathol 2012 Dec;25(12):1609-22. Epub 2012 Aug 10 doi: 10.1038/modpathol.2012.122. PMID: 22878649

Recent systematic reviews

Uijterwijk BA, Lemmers DH, Fusai GK, Zerbi A, Salvia R, Sparrelid E, White S, Björnsson B, Mavroeidis VK, Roberts KJ, Mazzola M, Cabús SS, Soonawalla Z, Korkolis D, Serradilla M, Pessaux P, Luyer M, Mowbray N, Ielpo B, Mazzotta A, Kleeff J, Boggi U, Muñoz MAS, Goh BKP, Andreotti E, Wilmink H, Ghidini M, Zaniboni A, Verbeke C, Adsay V, Bianchi D, Besselink MG, Abu Hilal M; International Study Group on Non-Pancreatic Periampullary Cancer (ISGACA)
Ann Surg Oncol 2024 Jul;31(7):4654-4664. Epub 2024 Apr 11 doi: 10.1245/s10434-024-15213-z. PMID: 38602578Free PMC Article

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