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AV Block Second Degree Mobitz Type I by ECG Finding

MedGen UID:
817654
•Concept ID:
C3811814
•
Finding
Synonyms: AV Block Second Degree Mobitz Type I; AV Block Second Degree Mobitz Type I by EKG Finding; AV Block Second Degree Möbitz Type I; AV Block Second Degree Möbitz Type I by ECG Finding; AV Block Second Degree Möbitz Type I by EKG Finding; Mobitz I; Mobitz Type I Second Degree AV Block; Möbitz I; Möbitz Type I Second Degree AV Block; Second Degree Atrioventricular Block Mobitz Type I; Second Degree Atrioventricular Block Möbitz Type I; Type 1 Second Degree Atrioventricular Block; Type 1 Second Degree AV Block; Wenckebach Block

Definition

An electrocardiographic finding of intermittent failure of atrial electrical impulse conduction to the ventricles, characterized by a progressively lengthening PR interval prior to the block of an atrial impulse. (CDISC) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAV Block Second Degree Mobitz Type I by ECG Finding

Professional guidelines

PubMed

Association between Atrioventricular Block and Mortality in Primary Care Patients: The CODE Study.
Paixão GMM, Lima EM, Quadros AB, Cabral DPR, Coelho RR, Oliveira DM, Nascimento JS, Gomes PR, Ribeiro AL
Arq Bras Cardiol 2022 Oct;119(4):564-571. doi: 10.36660/abc.20210763. PMID: 35857946Free PMC Article
Defining abnormal electrocardiography in adult emergency department syncope patients: the Ottawa Electrocardiographic Criteria.
Thiruganasambandamoorthy V, Hess EP, Turko E, Tran ML, Wells GA, Stiell IG
CJEM 2012 Jul;14(4):248-58. PMID: 22813399

Recent clinical studies

Etiology

High-risk atrioventricular block in Brugada syndrome patients with a history of syncope.
Kamakura T, Sacher F, Katayama K, Ueda N, Nakajima K, Wada M, Yamagata K, Ishibashi K, Inoue Y, Miyamoto K, Nagase S, Noda T, Aiba T, Nakatani Y, Ramirez FD, André C, Nakashima T, Krisai P, Takagi T, Tixier R, Chauvel R, Cheniti G, Duchateau J, Pambrun T, Derval N, Hocini M, Jais P, Haïssaguerre M, Kamakura S, Kusano K
J Cardiovasc Electrophysiol 2021 Mar;32(3):772-781. Epub 2021 Jan 19 doi: 10.1111/jce.14876. PMID: 33428312
Frequency and Significance of High-Degree Atrioventricular Block and Sinoatrial Node Dysfunction in Patients With Non-ST-Elevation Myocardial Infarction.
Misumida N, Ogunbayo GO, Kim SM, Abdel-Latif A, Ziada KM, Elayi CS
Am J Cardiol 2018 Nov 15;122(10):1598-1603. Epub 2018 Aug 21 doi: 10.1016/j.amjcard.2018.08.001. PMID: 30227965
Mobitz type I and II atrioventricular blocks during fingolimod therapy.
Saccà F, Puorro G, Marsili A, Pane C, Russo CV, Lanzillo R, de Rosa A, Cittadini A, De Angelis G, Brescia Morra V
Neurol Sci 2016 Sep;37(9):1557-9. Epub 2016 May 25 doi: 10.1007/s10072-016-2621-y. PMID: 27225279
Long-term follow-up of older patients with Mobitz type I second degree atrioventricular block.
Coumbe AG, Naksuk N, Newell MC, Somasundaram PE, Benditt DG, Adabag S
Heart 2013 Mar;99(5):334-8. Epub 2012 Oct 19 doi: 10.1136/heartjnl-2012-302770. PMID: 23086974
ECG variants and cardiac arrhythmias in athletes: clinical relevance and prognostic importance.
Zehender M, Meinertz T, Keul J, Just H
Am Heart J 1990 Jun;119(6):1378-91. doi: 10.1016/s0002-8703(05)80189-9. PMID: 2191578

Diagnosis

Mobitz type II second-degree atrioventricular block during sleep: true or false?
Barold SS
Herzschrittmacherther Elektrophysiol 2023 Sep;34(3):226-228. Epub 2023 Aug 4 doi: 10.1007/s00399-023-00959-y. PMID: 37540286
Problematic definitions of Mobitz type II second degree AV block: Historical aspects.
Barold SS
J Electrocardiol 2023 Jul-Aug;79:122-123. Epub 2023 Apr 3 doi: 10.1016/j.jelectrocard.2023.03.086. PMID: 37084494
Mobitz type I and II atrioventricular blocks during fingolimod therapy.
Saccà F, Puorro G, Marsili A, Pane C, Russo CV, Lanzillo R, de Rosa A, Cittadini A, De Angelis G, Brescia Morra V
Neurol Sci 2016 Sep;37(9):1557-9. Epub 2016 May 25 doi: 10.1007/s10072-016-2621-y. PMID: 27225279
Diagnostic and Prognostic Implications of Surface Recordings from Patients with Atrioventricular Block.
Nelson WP
Card Electrophysiol Clin 2016 Mar;8(1):25-35. doi: 10.1016/j.ccep.2015.10.031. PMID: 26920166
Second-degree atrioventricular block revisited.
Barold SS, Herweg B
Herzschrittmacherther Elektrophysiol 2012 Dec;23(4):296-304. Epub 2012 Dec 7 doi: 10.1007/s00399-012-0240-8. PMID: 23224264

Therapy

Comfrey herbal remedy causing second-degree heart block: do not be outfoxed by digitalis.
Vithayathil MK, Edwards M
BMJ Case Rep 2016 Dec 1;2016 doi: 10.1136/bcr-2016-216995. PMID: 27908913Free PMC Article
Mobitz type I and II atrioventricular blocks during fingolimod therapy.
Saccà F, Puorro G, Marsili A, Pane C, Russo CV, Lanzillo R, de Rosa A, Cittadini A, De Angelis G, Brescia Morra V
Neurol Sci 2016 Sep;37(9):1557-9. Epub 2016 May 25 doi: 10.1007/s10072-016-2621-y. PMID: 27225279
Trazodone and omeprazole interaction causing frequent second-degree Mobitz type 1 atrioventricular (AV) block (Wenckebach phenomenon) and syncope: a case report and literature review.
Akinseye OA, Alfishawy M, Radparvar F, Bakshi S
Am J Case Rep 2015 May 27;16:319-21. doi: 10.12659/AJCR.893427. PMID: 26017199Free PMC Article
Benzodiazepine-associated atrioventricular block.
Arroyo Plasencia AM, Ballentine LM, Mowry JB, Kao LW
Am J Ther 2012 Jan;19(1):e48-52. doi: 10.1097/MJT.0b013e3181dcf572. PMID: 20535011
Woldemar Mobitz and His 1924 classification of second-degree atrioventricular block.
Silverman ME, Upshaw CB Jr, Lange HW
Circulation 2004 Aug 31;110(9):1162-7. doi: 10.1161/01.CIR.0000140669.35049.34. PMID: 15339865

Prognosis

Frequency and Significance of High-Degree Atrioventricular Block and Sinoatrial Node Dysfunction in Patients With Non-ST-Elevation Myocardial Infarction.
Misumida N, Ogunbayo GO, Kim SM, Abdel-Latif A, Ziada KM, Elayi CS
Am J Cardiol 2018 Nov 15;122(10):1598-1603. Epub 2018 Aug 21 doi: 10.1016/j.amjcard.2018.08.001. PMID: 30227965
Diagnostic and Prognostic Implications of Surface Recordings from Patients with Atrioventricular Block.
Nelson WP
Card Electrophysiol Clin 2016 Mar;8(1):25-35. doi: 10.1016/j.ccep.2015.10.031. PMID: 26920166
Long-term follow-up of older patients with Mobitz type I second degree atrioventricular block.
Coumbe AG, Naksuk N, Newell MC, Somasundaram PE, Benditt DG, Adabag S
Heart 2013 Mar;99(5):334-8. Epub 2012 Oct 19 doi: 10.1136/heartjnl-2012-302770. PMID: 23086974
Second-degree atrioventricular block: Mobitz type II.
Wogan JM, Lowenstein SR, Gordon GS
J Emerg Med 1993 Jan-Feb;11(1):47-54. doi: 10.1016/0736-4679(93)90009-v. PMID: 8445186
ECG variants and cardiac arrhythmias in athletes: clinical relevance and prognostic importance.
Zehender M, Meinertz T, Keul J, Just H
Am Heart J 1990 Jun;119(6):1378-91. doi: 10.1016/s0002-8703(05)80189-9. PMID: 2191578

Clinical prediction guides

Frequency and Significance of High-Degree Atrioventricular Block and Sinoatrial Node Dysfunction in Patients With Non-ST-Elevation Myocardial Infarction.
Misumida N, Ogunbayo GO, Kim SM, Abdel-Latif A, Ziada KM, Elayi CS
Am J Cardiol 2018 Nov 15;122(10):1598-1603. Epub 2018 Aug 21 doi: 10.1016/j.amjcard.2018.08.001. PMID: 30227965
Mobitz type I and II atrioventricular blocks during fingolimod therapy.
Saccà F, Puorro G, Marsili A, Pane C, Russo CV, Lanzillo R, de Rosa A, Cittadini A, De Angelis G, Brescia Morra V
Neurol Sci 2016 Sep;37(9):1557-9. Epub 2016 May 25 doi: 10.1007/s10072-016-2621-y. PMID: 27225279
Long-term follow-up of older patients with Mobitz type I second degree atrioventricular block.
Coumbe AG, Naksuk N, Newell MC, Somasundaram PE, Benditt DG, Adabag S
Heart 2013 Mar;99(5):334-8. Epub 2012 Oct 19 doi: 10.1136/heartjnl-2012-302770. PMID: 23086974
Intra-His bundle block. Clinical, electrocardiographic, and electrophysiologic characteristics.
Andrea EM, Atie J, Maciel WA, de Oliveira NA Jr, Camanho LE, Belo LG, de Carvalho HA, Siqueira L, Saad E, Venancio AC
Arq Bras Cardiol 2002 Nov;79(5):526-37. PMID: 12447503
ECG variants and cardiac arrhythmias in athletes: clinical relevance and prognostic importance.
Zehender M, Meinertz T, Keul J, Just H
Am Heart J 1990 Jun;119(6):1378-91. doi: 10.1016/s0002-8703(05)80189-9. PMID: 2191578

Recent systematic reviews

Predictors of Permanent Pacemaker Implantation in Patients Undergoing Transcatheter Aortic Valve Replacement - A Systematic Review and Meta-Analysis.
Ullah W, Zahid S, Zaidi SR, Sarvepalli D, Haq S, Roomi S, Mukhtar M, Khan MA, Gowda SN, Ruggiero N, Vishnevsky A, Fischman DL
J Am Heart Assoc 2021 Jul 20;10(14):e020906. Epub 2021 Jul 14 doi: 10.1161/JAHA.121.020906. PMID: 34259045Free PMC Article

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