U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tubulovillous adenoma

MedGen UID:
83125
Concept ID:
C0334307
Neoplastic Process
Synonyms: Gastrointestinal Tract Tubulovillous Adenoma; GI Tract Tubulovillous Adenoma; Papillotubular adenoma; Tubulo-papillary adenoma; Tubulovillous Adenoma; tubulovillous adenoma; Villoglandular adenoma
SNOMED CT: Tubulovillous adenoma (61722000); Villoglandular adenoma (61722000); Papillotubular adenoma (61722000); Tubulo-papillary adenoma (61722000)
 
Monarch Initiative: MONDO:0024661

Definition

An adenoma arising from the glandular epithelium of the gastrointestinal tract. It is characterized by the presence of a tubular and a villous architectural pattern. Most often it occurs in the large intestine, small intestine, and the stomach. The neoplastic epithelial cells show dysplastic features. [from NCI]

Professional guidelines

PubMed

Cansiz Ersöz C, Kiremitci S, Savas B, Ensari A
Acta Gastroenterol Belg 2020 Oct-Dec;83(4):549-556. PMID: 33321010
Tamer F, Yuksel ME
Dermatol Ther 2020 Jul;33(4):e13720. Epub 2020 Jun 29 doi: 10.1111/dth.13720. PMID: 32506694
Rea JD, Lockhart ME, Yarbrough DE, Leeth RR, Bledsoe SE, Clements RH
Am Surg 2007 Nov;73(11):1098-105. PMID: 18092641

Recent clinical studies

Etiology

Li LC, Zheng LR, Han N
Clin Imaging 2022 Feb;82:135-138. Epub 2021 Nov 18 doi: 10.1016/j.clinimag.2021.11.015. PMID: 34813992
Lo KW, Blitzer DN, Shoucair S, Lisle DM
Surg Endosc 2022 Jan;36(1):793-799. Epub 2021 Jan 8 doi: 10.1007/s00464-020-08257-1. PMID: 33416992
Zhang Y, Pan M, Li CY, Li JY, Ge W, Xu L, Xiao Y
Bioengineered 2021 Dec;12(1):6831-6843. doi: 10.1080/21655979.2021.1971036. PMID: 34585630Free PMC Article
Bateman AC
Histopathology 2021 May;78(6):780-790. Epub 2021 Jan 31 doi: 10.1111/his.14305. PMID: 33332664
Ackroyd FW, Hedberg SE
Annu Rev Med 1985;36:619-25. doi: 10.1146/annurev.me.36.020185.003155. PMID: 3994327

Diagnosis

Marcinkevičiūtė K, Kryžauskas M, Poškus T
Medicina (Kaunas) 2023 Mar 22;59(3) doi: 10.3390/medicina59030633. PMID: 36984634Free PMC Article
Li LC, Zheng LR, Han N
Clin Imaging 2022 Feb;82:135-138. Epub 2021 Nov 18 doi: 10.1016/j.clinimag.2021.11.015. PMID: 34813992
Bateman AC
Histopathology 2021 May;78(6):780-790. Epub 2021 Jan 31 doi: 10.1111/his.14305. PMID: 33332664
Singhal M, Kang M, Narayanan S, Gupta R, Wig JD, Bal A
J Gastrointest Surg 2009 Feb;13(2):386-8. Epub 2008 Apr 4 doi: 10.1007/s11605-008-0509-8. PMID: 18389325
Ackroyd FW, Hedberg SE
Annu Rev Med 1985;36:619-25. doi: 10.1146/annurev.me.36.020185.003155. PMID: 3994327

Therapy

Wang ZK, Liu F, Wang Y, Wang XD, Tang P, Li W
World J Gastroenterol 2020 Oct 7;26(37):5673-5681. doi: 10.3748/wjg.v26.i37.5673. PMID: 33088160Free PMC Article
Pezhouh MK, Burgart LJ, Chiu K, Cohen DA, Hutchings DA, Sanderson SO, Shirazi M, Stanich PP, VandenBussche CJ, Voltaggio L, Willhoit ED, Xue Y, Arnold CA
Am J Surg Pathol 2020 Jun;44(6):793-798. doi: 10.1097/PAS.0000000000001435. PMID: 31934919
Song M, Lee IM, Manson JE, Buring JE, Dushkes R, Gordon D, Walter J, Wu K, Chan AT, Ogino S, Fuchs CS, Meyerhardt JA, Giovannucci EL; VITAL Research Group
JAMA Oncol 2020 Jan 1;6(1):108-115. doi: 10.1001/jamaoncol.2019.4587. PMID: 31750855Free PMC Article
Koritala T, Zolotarevsky E, Bartley AN, Ellis CD, Krolikowski JA, Burton J, Gunaratnam NT
Gastrointest Endosc 2015 Apr;81(4):985-8. Epub 2014 Nov 22 doi: 10.1016/j.gie.2014.09.043. PMID: 25440288
Scozzari G, Trapani R, Toppino M, Morino M
Surg Obes Relat Dis 2013 Jan-Feb;9(1):133-42. Epub 2012 Oct 12 doi: 10.1016/j.soard.2012.10.002. PMID: 23265766

Prognosis

Li LC, Zheng LR, Han N
Clin Imaging 2022 Feb;82:135-138. Epub 2021 Nov 18 doi: 10.1016/j.clinimag.2021.11.015. PMID: 34813992
Kharin L, Bychkov I, Karnaukhov N, Voloshin M, Fazliyeva R, Deneka A, Frantsiyants E, Kit O, Golemis E, Boumber Y
PLoS One 2021;16(7):e0252132. Epub 2021 Jul 8 doi: 10.1371/journal.pone.0252132. PMID: 34237057Free PMC Article
Laish I, Seregeev I, Naftali T, Konikoff FM
Dig Liver Dis 2017 Oct;49(10):1115-1120. Epub 2017 May 16 doi: 10.1016/j.dld.2017.05.005. PMID: 28641945
Bodin R, Peycru T, Schwartz A, Jarry J, Pommier N, Durand-Dastes F
Gastroenterol Clin Biol 2010 Nov;34(11):633-5. Epub 2010 Aug 23 doi: 10.1016/j.gcb.2010.07.006. PMID: 20739133
Ackroyd FW, Hedberg SE
Annu Rev Med 1985;36:619-25. doi: 10.1146/annurev.me.36.020185.003155. PMID: 3994327

Clinical prediction guides

Gomez Cifuentes JD, Berger S, Caskey K, Jove A, Sealock R, Hair C, Velez M, Jarbrink-Sehgal M, Thrift AP, da Costa WL Jr, Gyanprakash K
Dig Dis Sci 2023 Oct;68(10):3935-3942. Epub 2023 Aug 7 doi: 10.1007/s10620-023-08054-5. PMID: 37548897
Jiang AC, Buckingham L, Bishehsari F, Sutherland S, Ma K, Melson JE
Clin Transl Gastroenterol 2021 Jun 1;12(6):e00369. doi: 10.14309/ctg.0000000000000369. PMID: 34060495Free PMC Article
Laish I, Seregeev I, Naftali T, Konikoff FM
Dig Liver Dis 2017 Oct;49(10):1115-1120. Epub 2017 May 16 doi: 10.1016/j.dld.2017.05.005. PMID: 28641945
Binmoeller KF, Hamerski CM, Shah JN, Bhat YM, Kane SD
Gastrointest Endosc 2016 Mar;83(3):638-42. Epub 2015 Sep 14 doi: 10.1016/j.gie.2015.08.079. PMID: 26375437
Kawasaki T, Nosho K, Ohnishi M, Suemoto Y, Glickman JN, Chan AT, Kirkner GJ, Mino-Kenudson M, Fuchs CS, Ogino S
BMC Cancer 2008 Jan 29;8:33. doi: 10.1186/1471-2407-8-33. PMID: 18230181Free PMC Article

Recent systematic reviews

Scozzari G, Trapani R, Toppino M, Morino M
Surg Obes Relat Dis 2013 Jan-Feb;9(1):133-42. Epub 2012 Oct 12 doi: 10.1016/j.soard.2012.10.002. PMID: 23265766

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...