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Benign neoplasm of nasal cavity

MedGen UID:
83859
•Concept ID:
C0347215
•
Neoplastic Process
Synonyms: Benign Nasal Cavity Neoplasm; benign nasal cavity neoplasm; Benign Nasal Cavity Tumor; benign nasal cavity tumor; benign nasal cavity tumour; Benign Neoplasm of Nasal Cavity; benign neoplasm of nasal cavity; Benign Neoplasm of the Nasal Cavity; benign neoplasm of the nasal cavity; Benign tumor of nasal cavity; Benign Tumor of Nasal Cavity; benign tumor of nasal cavity; Benign Tumor of the Nasal Cavity; benign tumor of the nasal cavity; benign tumour of nasal cavity; benign tumour of the nasal cavity; nasal cavity benign neoplasm
SNOMED CT: Benign tumor of nasal cavity (92241005); Benign neoplasm of nasal cavity (92241005)
 
Monarch Initiative: MONDO:0021475

Definition

A neoplasm that arises from the nasal cavity and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. Representative examples include Schneiderian papilloma and salivary gland-type adenoma. [from NCI]

Professional guidelines

PubMed

The contemporary management of cancers of the sinonasal tract in adults.
Thawani R, Kim MS, Arastu A, Feng Z, West MT, Taflin NF, Thein KZ, Li R, Geltzeiler M, Lee N, Fuller CD, Grandis JR, Floudas CS, Heinrich MC, Hanna E, Chandra RA
CA Cancer J Clin 2023 Jan;73(1):72-112. Epub 2022 Aug 2 doi: 10.3322/caac.21752. PMID: 35916666Free PMC Article
Current opinions on diagnosis and treatment of adenoid cystic carcinoma.
Fang Y, Peng Z, Wang Y, Gao K, Liu Y, Fan R, Zhang H, Xie Z, Jiang W
Oral Oncol 2022 Jul;130:105945. Epub 2022 Jun 2 doi: 10.1016/j.oraloncology.2022.105945. PMID: 35662026
Selection of lymph node target volumes for definitive head and neck radiation therapy: a 2019 Update.
Biau J, Lapeyre M, Troussier I, Budach W, Giralt J, Grau C, Kazmierska J, Langendijk JA, Ozsahin M, O'Sullivan B, Bourhis J, Grégoire V
Radiother Oncol 2019 May;134:1-9. Epub 2019 Jan 30 doi: 10.1016/j.radonc.2019.01.018. PMID: 31005201

Recent clinical studies

Etiology

Update on olfactory neuroblastoma.
Lopez F, Agaimy A, Franchi A, Suárez C, Vander Poorten V, Mäkitie AA, Homma A, Eisbruch A, Olsen KD, Saba NF, Nuyts S, Snyderman C, Beitler JJ, Corry J, Hanna E, Hellquist H, Rinaldo A, Ferlito A
Virchows Arch 2024 Apr;484(4):567-585. Epub 2024 Feb 22 doi: 10.1007/s00428-024-03758-z. PMID: 38386106
Neurilemmoma of the Nasal Cavity and Paranasal Sinuses.
He X, Wang Y
Ear Nose Throat J 2023 Jul;102(7):NP364-NP368. Epub 2021 May 5 doi: 10.1177/01455613211007947. PMID: 33951978
Introduction.
Bishop JA
Semin Diagn Pathol 2016 Mar;33(2):61. Epub 2015 Dec 29 doi: 10.1053/j.semdp.2015.12.002. PMID: 26754864
Infrasellar craniopharyngioma.
Yu X, Liu R, Wang Y, Wang H, Zhao H, Wu Z
Clin Neurol Neurosurg 2012 Feb;114(2):112-9. Epub 2011 Oct 21 doi: 10.1016/j.clineuro.2011.09.010. PMID: 22018920
Esthesioneuroblastoma.
Elkon D, Hightower SI, Lim ML, Cantrell RW, Constable WC
Cancer 1979 Sep;44(3):1087-94. doi: 10.1002/1097-0142(197909)44:3<1087::aid-cncr2820440343>3.0.co;2-a. PMID: 383268

Diagnosis

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Nasal Cavity, Paranasal Sinuses and Skull Base.
Thompson LDR, Bishop JA
Head Neck Pathol 2022 Mar;16(1):1-18. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01406-5. PMID: 35312976Free PMC Article
Olfactory Neuroblastoma.
Veyrat M, Vérillaud B, Fiaux-Camous D, Froelich S, Bresson D, Nicolai P, Herman P
Adv Otorhinolaryngol 2020;84:154-167. Epub 2020 Jul 30 doi: 10.1159/000457935. PMID: 32731231
Esthesioneuroblastoma: A Comprehensive Review of Diagnosis, Management, and Current Treatment Options.
Fiani B, Quadri SA, Cathel A, Farooqui M, Ramachandran A, Siddiqi I, Ghanchi H, Zafar A, Berman BW, Siddiqi J
World Neurosurg 2019 Jun;126:194-211. Epub 2019 Mar 9 doi: 10.1016/j.wneu.2019.03.014. PMID: 30862589
Sinonasal angioleiomyoma.
Lau YW, Vikneswaran T, Tan TY, Tang IP
Med J Malaysia 2016 Jun;71(3):154-5. PMID: 27495895
Olfactory neuroblastoma.
Thompson LD
Head Neck Pathol 2009 Sep;3(3):252-9. Epub 2009 Jul 16 doi: 10.1007/s12105-009-0125-2. PMID: 20596981Free PMC Article

Therapy

Pediatric pituitary adenomas.
Walz PC, Drapeau A, Shaikhouni A, Eide J, Rugino AJ, Mohyeldin A, Carrau R, Prevedello D
Childs Nerv Syst 2019 Nov;35(11):2107-2118. Epub 2019 Jul 13 doi: 10.1007/s00381-019-04293-y. PMID: 31302729
Esthesioneuroblastoma: A Comprehensive Review of Diagnosis, Management, and Current Treatment Options.
Fiani B, Quadri SA, Cathel A, Farooqui M, Ramachandran A, Siddiqi I, Ghanchi H, Zafar A, Berman BW, Siddiqi J
World Neurosurg 2019 Jun;126:194-211. Epub 2019 Mar 9 doi: 10.1016/j.wneu.2019.03.014. PMID: 30862589
Avoiding complications in endoscopic skull base surgery.
Constantinidis J, Konstantinidis I
Curr Opin Otolaryngol Head Neck Surg 2017 Feb;25(1):79-85. doi: 10.1097/MOO.0000000000000327. PMID: 28027059
Nasopharyngeal carcinoma.
Brennan B
Orphanet J Rare Dis 2006 Jun 26;1:23. doi: 10.1186/1750-1172-1-23. PMID: 16800883Free PMC Article
Esthesioneuroblastoma.
Klepin HD, McMullen KP, Lesser GJ
Curr Treat Options Oncol 2005 Nov;6(6):509-18. doi: 10.1007/s11864-005-0029-7. PMID: 16242055

Prognosis

Olfactory Neuroblastoma.
Veyrat M, Vérillaud B, Fiaux-Camous D, Froelich S, Bresson D, Nicolai P, Herman P
Adv Otorhinolaryngol 2020;84:154-167. Epub 2020 Jul 30 doi: 10.1159/000457935. PMID: 32731231
Sinonasal angioleiomyoma.
Lau YW, Vikneswaran T, Tan TY, Tang IP
Med J Malaysia 2016 Jun;71(3):154-5. PMID: 27495895
Lethal Epistaxis.
Byard RW
J Forensic Sci 2016 Sep;61(5):1244-9. Epub 2016 Jun 10 doi: 10.1111/1556-4029.13119. PMID: 27282512
Introduction.
Bishop JA
Semin Diagn Pathol 2016 Mar;33(2):61. Epub 2015 Dec 29 doi: 10.1053/j.semdp.2015.12.002. PMID: 26754864
Infrasellar craniopharyngioma.
Yu X, Liu R, Wang Y, Wang H, Zhao H, Wu Z
Clin Neurol Neurosurg 2012 Feb;114(2):112-9. Epub 2011 Oct 21 doi: 10.1016/j.clineuro.2011.09.010. PMID: 22018920

Clinical prediction guides

Recurrence morbidity of olfactory neuroblastoma.
Melder K, Mace JC, Choby G, Almeida JP, Champagne PO, Chan E, Ciporen J, Chaskes MB, Fernandez-Miranda J, Fung NK, Gardner P, Hwang P, Ji KSY, Kalyvas A, Kong KA, Patel C, Patel Z, Celda MP, Pinheiro-Neto CD, Snyderman C, Thorp BD, Van Gompel JJ, Zenonos G, Zwagerman NT, Sanusi O, Wang EW, Geltzeiler M
Int Forum Allergy Rhinol 2024 Sep;14(9):1435-1445. Epub 2024 Apr 3 doi: 10.1002/alr.23351. PMID: 38567900
Update on olfactory neuroblastoma.
Lopez F, Agaimy A, Franchi A, Suárez C, Vander Poorten V, Mäkitie AA, Homma A, Eisbruch A, Olsen KD, Saba NF, Nuyts S, Snyderman C, Beitler JJ, Corry J, Hanna E, Hellquist H, Rinaldo A, Ferlito A
Virchows Arch 2024 Apr;484(4):567-585. Epub 2024 Feb 22 doi: 10.1007/s00428-024-03758-z. PMID: 38386106
Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma.
Lechner M, Takahashi Y, Turri-Zanoni M, Liu J, Counsell N, Hermsen M, Kaur RP, Zhao T, Ramanathan M Jr, Schartinger VH, Emanuel O, Helman S, Varghese J, Dudas J, Riechelmann H, Sprung S, Haybaeck J, Howard D, Engel NW, Stewart S, Brooks L, Pickles JC, Jacques TS, Fenton TR, Williams L, Vaz FM, O'Flynn P, Stimpson P, Wang S, Hannan SA, Unadkat S, Hughes J, Dwivedi R, Forde CT, Randhawa P, Gane S, Joseph J, Andrews PJ, Royle G, Franchi A, Maragliano R, Battocchio S, Bewicke-Copley H, Pipinikas C, Webster A, Thirlwell C, Ho D, Teschendorff A, Zhu T, Steele CD, Pillay N, Vanhaesebroeck B, Mohyeldin A, Fernandez-Miranda J, Park KW, Le QT, West RB, Saade R, Manes RP, Omay SB, Vining EM, Judson BL, Yarbrough WG, Sansovini M, Silvia N, Grassi I, Bongiovanni A, Capper D, Schüller U, Thavaraj S, Sandison A, Surda P, Hopkins C, Ferrari M, Mattavelli D, Rampinelli V, Facchetti F, Nicolai P, Bossi P, Henriquez OA, Magliocca K, Solares CA, Wise SK, Llorente JL, Patel ZM, Nayak JV, Hwang PH, Lacy PD, Woods R, O'Neill JP, Jay A, Carnell D, Forster MD, Ishii M, London NR Jr, Bell DM, Gallia GL, Castelnuovo P, Severi S, Lund VJ, Hanna EY
Eur J Cancer 2022 Feb;162:221-236. Epub 2021 Dec 31 doi: 10.1016/j.ejca.2021.09.046. PMID: 34980502Free PMC Article
Histopathologic features of nasal glial heterotopia (nasal glioma).
Gilani A, Kleinschmidt-DeMasters BK
Childs Nerv Syst 2022 Jan;38(1):63-75. Epub 2021 Sep 25 doi: 10.1007/s00381-021-05369-4. PMID: 34562130
Infrasellar craniopharyngioma.
Yu X, Liu R, Wang Y, Wang H, Zhao H, Wu Z
Clin Neurol Neurosurg 2012 Feb;114(2):112-9. Epub 2011 Oct 21 doi: 10.1016/j.clineuro.2011.09.010. PMID: 22018920

Recent systematic reviews

Overall and disease-specific survival of sinonasal adenoid cystic carcinoma: a systematic review and meta-analysis.
Mauthe T, Holzmann D, Soyka MB, Mueller SA, Balermpas P, Held U, Freiberger SN, Rupp NJ, Meerwein CM
Rhinology 2023 Dec 1;61(6):508-518. doi: 10.4193/Rhin23.204. PMID: 37703531
Diagnosis, Treatment and Follow-Up of Sinonasal Leiomyomas: A Systematic Review.
Runge A, Randhawa A, Mayo-Patiño M, Santer M, Hartl R, Dejaco D, Eloy JA
Am J Rhinol Allergy 2023 Sep;37(5):586-592. Epub 2023 Apr 24 doi: 10.1177/19458924231170464. PMID: 37093753
Expert Consensus Statement: Management of Dysphagia in Head and Neck Cancer Patients.
Kuhn MA, Gillespie MB, Ishman SL, Ishii LE, Brody R, Cohen E, Dhar SI, Hutcheson K, Jefferson G, Johnson F, Rameau A, Sher D, Starmer H, Strohl M, Ulmer K, Vaitaitis V, Begum S, Batjargal M, Dhepyasuwan N
Otolaryngol Head Neck Surg 2023 Apr;168(4):571-592. doi: 10.1002/ohn.302. PMID: 36965195
Sino-nasal hemangiopericytoma: a case series and systematic literature review.
Warman M, Syn-Hershko A, Cohen O, Tzipin Y, Lahav Y, Tessler I
Eur Arch Otorhinolaryngol 2022 Aug;279(8):3989-3996. Epub 2022 Feb 1 doi: 10.1007/s00405-021-07239-w. PMID: 35103868
Isolated sphenoid sinus opacification: A systematic review.
Knisely A, Holmes T, Barham H, Sacks R, Harvey R
Am J Otolaryngol 2017 Mar-Apr;38(2):237-243. Epub 2017 Jan 19 doi: 10.1016/j.amjoto.2017.01.014. PMID: 28129912

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