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Recurrent Merkel Cell Carcinoma

MedGen UID:
853031
•Concept ID:
C0935808
•
Neoplastic Process
Synonym: Recurrent Neuroendocrine Carcinoma of the Skin

Definition

The reemergence of Merkel cell carcinoma after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Merkel Cell Carcinoma

Professional guidelines

PubMed

Benefits of combined modality treatment of Merkel cell carcinoma of the head and neck: single institution experience.
Balakrishnan V, Berry S, Stew B, Sizeland A
J Laryngol Otol 2013 Sep;127(9):908-16. Epub 2013 Aug 19 doi: 10.1017/S0022215113001862. PMID: 23952972
Treatment of recurrent Merkel cell carcinoma: an analysis of 46 cases.
Eng TY, Naguib M, Fuller CD, Jones WE 3rd, Herman TS
Am J Clin Oncol 2004 Dec;27(6):576-83. doi: 10.1097/01.coc.0000135926.93116.c7. PMID: 15577435

Recent clinical studies

Etiology

Benefits of combined modality treatment of Merkel cell carcinoma of the head and neck: single institution experience.
Balakrishnan V, Berry S, Stew B, Sizeland A
J Laryngol Otol 2013 Sep;127(9):908-16. Epub 2013 Aug 19 doi: 10.1017/S0022215113001862. PMID: 23952972
Quality of life outcomes after isolated limb infusion.
McClaine RJ, Giglia JS, Ahmad SA, McCoy SJ, Sussman JJ
Ann Surg Oncol 2012 May;19(5):1373-8. doi: 10.1245/s10434-012-2239-0. PMID: 22302268
Treatment of recurrent Merkel cell carcinoma: an analysis of 46 cases.
Eng TY, Naguib M, Fuller CD, Jones WE 3rd, Herman TS
Am J Clin Oncol 2004 Dec;27(6):576-83. doi: 10.1097/01.coc.0000135926.93116.c7. PMID: 15577435
Recurrent Merkel cell carcinoma of the upper extremity.
Metzinger SE, Wolfer RS, Disa JJ, Kupersmith JE, Robertson BC
South Med J 2000 Mar;93(3):340-5. PMID: 10728530

Diagnosis

A Case Report of Leptomeningeal Carcinomatosis Secondary to Recurrent Merkel Cell Carcinoma after Avelumab.
Mendoza P, Chuang KL
Perm J 2021 May;25 doi: 10.7812/TPP/20.235. PMID: 33970097Free PMC Article
A case report of recurrent Merkel cell carcinoma with synchronous metastases to the heart and stomach.
Ha JY, Park SE, Kim HS, Won H, Kim BJ, Hwang IG
Medicine (Baltimore) 2018 Nov;97(44):e13032. doi: 10.1097/MD.0000000000013032. PMID: 30383666Free PMC Article
Combined Merkel cell carcinoma and atypical fibroxanthoma.
Youker SR, Billingsley EM
J Cutan Med Surg 2005 Jan;9(1):6-9. doi: 10.1007/s10227-005-0024-4. PMID: 16208439
Recurrent Merkel cell carcinoma of the upper extremity.
Metzinger SE, Wolfer RS, Disa JJ, Kupersmith JE, Robertson BC
South Med J 2000 Mar;93(3):340-5. PMID: 10728530

Therapy

A Case Report of Leptomeningeal Carcinomatosis Secondary to Recurrent Merkel Cell Carcinoma after Avelumab.
Mendoza P, Chuang KL
Perm J 2021 May;25 doi: 10.7812/TPP/20.235. PMID: 33970097Free PMC Article
Recurrent Merkel cell carcinoma of the testis with unknown primary site: a case report.
Mweempwa A, Tan A, Dray M
J Med Case Rep 2016 Nov 5;10(1):314. doi: 10.1186/s13256-016-1102-5. PMID: 27814751Free PMC Article
Quality of life outcomes after isolated limb infusion.
McClaine RJ, Giglia JS, Ahmad SA, McCoy SJ, Sussman JJ
Ann Surg Oncol 2012 May;19(5):1373-8. doi: 10.1245/s10434-012-2239-0. PMID: 22302268
Computed tomography evaluation of recurrent Merkel cell carcinoma.
Orr LA, Sotile SC, Byram BR, Brogdon BG
Clin Imaging 1992 Jan-Mar;16(1):52-4. doi: 10.1016/0899-7071(92)90092-n. PMID: 1540865

Prognosis

A Case Report of Leptomeningeal Carcinomatosis Secondary to Recurrent Merkel Cell Carcinoma after Avelumab.
Mendoza P, Chuang KL
Perm J 2021 May;25 doi: 10.7812/TPP/20.235. PMID: 33970097Free PMC Article
Multiple gastrointestinal metastases of Merkel cell carcinoma.
Poškus E, Platkevičius G, Simanskaitė V, Rimkevičiūtė E, Petrulionis M, Strupas K
Medicina (Kaunas) 2016;52(5):321-324. Epub 2016 Sep 20 doi: 10.1016/j.medici.2016.09.001. PMID: 27707579
Quality of life outcomes after isolated limb infusion.
McClaine RJ, Giglia JS, Ahmad SA, McCoy SJ, Sussman JJ
Ann Surg Oncol 2012 May;19(5):1373-8. doi: 10.1245/s10434-012-2239-0. PMID: 22302268
Combined Merkel cell carcinoma and atypical fibroxanthoma.
Youker SR, Billingsley EM
J Cutan Med Surg 2005 Jan;9(1):6-9. doi: 10.1007/s10227-005-0024-4. PMID: 16208439
Treatment of recurrent Merkel cell carcinoma: an analysis of 46 cases.
Eng TY, Naguib M, Fuller CD, Jones WE 3rd, Herman TS
Am J Clin Oncol 2004 Dec;27(6):576-83. doi: 10.1097/01.coc.0000135926.93116.c7. PMID: 15577435

Clinical prediction guides

Recurrent Merkel cell carcinoma of the gluteal region: A case report.
Turkkan G, Agdogan O, Saynak M, Uygun AC, Ustun F
Dermatol Ther 2019 Jan;32(1):e12749. Epub 2018 Oct 11 doi: 10.1111/dth.12749. PMID: 30238578

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