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Solid Carcinoma

MedGen UID:: 87212
•Concept ID:: C0334296
•: Neoplastic Process

Synonyms:	Solid adenocarcinoma with mucin formation; Solid carcinoma; Solid carcinoma with mucin formation
SNOMED CT:	Solid carcinoma (81920005); Solid carcinoma with mucin formation (81920005); Solid adenocarcinoma with mucin formation (81920005)

Definition

A carcinoma morphologically characterized by the presence of solid sheets of malignant epithelial cells in tissues. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVSolid Carcinoma

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Neoplasm
      - Epithelial neoplasm
        Carcinoma
        Solid Carcinoma
        Breast Ductal Carcinoma In Situ, Solid Type
        Prostate Ductal Adenocarcinoma, Solid Pattern
        Skin Nodular Solid Basal Cell Carcinoma
        Solid Lung Adenocarcinoma
        Solid papillary breast carcinoma
        Breast Solid Papillary Carcinoma In Situ
        Invasive Breast Solid Papillary Carcinoma
        Trabecular follicular adenocarcinoma

Professional guidelines

PubMed

AGA Clinical Practice Update on Lifestyle Modification Using Diet and Exercise to Achieve Weight Loss in the Management of Nonalcoholic Fatty Liver Disease: Expert Review.

Younossi ZM, Corey KE, Lim JK
Gastroenterology 2021 Feb;160(3):912-918. Epub 2020 Dec 9 doi: 10.1053/j.gastro.2020.11.051. PMID: 33307021

Irinotecan: 25 years of cancer treatment.

Bailly C
Pharmacol Res 2019 Oct;148:104398. Epub 2019 Aug 12 doi: 10.1016/j.phrs.2019.104398. PMID: 31415916

Differential diagnosis of solid carcinoma in situ.

Maluf HM
Semin Diagn Pathol 2004 Feb;21(1):25-31. doi: 10.1053/j.semdp.2003.10.009. PMID: 15074556

See all (11)

Recent clinical studies

Etiology

Successful neoadjuvant chemotherapy plus sintilimab for locally advanced cervical cancer: case series and review of the literature.

Liu L, Deng X, Guo S, Yang S
Diagn Pathol 2023 Sep 26;18(1):107. doi: 10.1186/s13000-023-01394-w. PMID: 37752528 Free PMC Article

Dedifferentiation-like tubular and solid carcinoma of the stomach shows phenotypic divergence and association with deficient SWI/SNF complex.

Huang SC, Chen KH, Ng KF, Lin IC, Chao YC, Yeh TS, Chuang HC, Chen TC
Virchows Arch 2022 Apr;480(4):771-781. Epub 2022 Feb 4 doi: 10.1007/s00428-022-03288-6. PMID: 35122125

Solid-type poorly differentiated adenocarcinoma of the stomach: Deficiency of mismatch repair and SWI/SNF complex.

Tsuruta S, Kohashi K, Yamada Y, Fujiwara M, Koga Y, Ihara E, Ogawa Y, Oki E, Nakamura M, Oda Y
Cancer Sci 2020 Mar;111(3):1008-1019. Epub 2020 Jan 28 doi: 10.1111/cas.14301. PMID: 31922331 Free PMC Article

Apoptosis and oxidative stress as relevant mechanisms of antitumor activity and genotoxicity of ZnO-NPs alone and in combination with N-acetyl cysteine in tumor-bearing mice.

El-Shorbagy HM, Eissa SM, Sabet S, El-Ghor AA
Int J Nanomedicine 2019;14:3911-3928. Epub 2019 May 27 doi: 10.2147/IJN.S204757. PMID: 31213808 Free PMC Article

Platinum derivatives during pregnancy in cervical cancer: a systematic review and meta-analysis.

Zagouri F, Sergentanis TN, Chrysikos D, Bartsch R
Obstet Gynecol 2013 Feb;121(2 Pt 1):337-343. doi: 10.1097/AOG.0b013e31827c5822. PMID: 23344284

See all (31)

Diagnosis

Unusual Case of Splenic Metastasis in Adenosquamous Carcinoma of the Cervix Uteri: Diagnosis and Treatment Considerations.

Klamminger GG, Burgard C, Rosar F, Altmeyer K, Malinowski M, Nigdelis MP, Stahl PR, Solomayer EF, Haj Hamoud B
Am J Case Rep 2023 Dec 8;24:e941600. doi: 10.12659/AJCR.941600. PMID: 38062677 Free PMC Article

MiR-29b suppresses proliferation and mobility by targeting SOX12 and DNMT3b in pancreatic cancer.

Wang L, Wang Z, Huang L, Wu C, Zhang B
Anticancer Drugs 2019 Mar;30(3):281-288. doi: 10.1097/CAD.0000000000000719. PMID: 30601190

Solid carcinoma revisited: a possible variant of microcystic adnexal carcinoma.

Lai JH, Limacher JJ, Richards RN
Am J Dermatopathol 2014 Nov;36(11):925-7. doi: 10.1097/DAD.0000000000000037. PMID: 25343214

Platinum derivatives during pregnancy in cervical cancer: a systematic review and meta-analysis.

Zagouri F, Sergentanis TN, Chrysikos D, Bartsch R
Obstet Gynecol 2013 Feb;121(2 Pt 1):337-343. doi: 10.1097/AOG.0b013e31827c5822. PMID: 23344284

Differential diagnosis of solid carcinoma in situ.

Maluf HM
Semin Diagn Pathol 2004 Feb;21(1):25-31. doi: 10.1053/j.semdp.2003.10.009. PMID: 15074556

See all (22)

Therapy

Successful neoadjuvant chemotherapy plus sintilimab for locally advanced cervical cancer: case series and review of the literature.

Liu L, Deng X, Guo S, Yang S
Diagn Pathol 2023 Sep 26;18(1):107. doi: 10.1186/s13000-023-01394-w. PMID: 37752528 Free PMC Article

Pharmacological basis of tanshinone and new insights into tanshinone as a multitarget natural product for multifaceted diseases.

Li Z, Zou J, Cao D, Ma X
Biomed Pharmacother 2020 Oct;130:110599. Epub 2020 Aug 18 doi: 10.1016/j.biopha.2020.110599. PMID: 33236719

Irinotecan: 25 years of cancer treatment.

Bailly C
Pharmacol Res 2019 Oct;148:104398. Epub 2019 Aug 12 doi: 10.1016/j.phrs.2019.104398. PMID: 31415916

Effect of hesperidin on mice bearing Ehrlich solid carcinoma maintained on doxorubicin.

Khedr NF, Khalil RM
Tumour Biol 2015 Dec;36(12):9267-75. Epub 2015 Jun 23 doi: 10.1007/s13277-015-3655-0. PMID: 26099723

Platinum derivatives during pregnancy in cervical cancer: a systematic review and meta-analysis.

Zagouri F, Sergentanis TN, Chrysikos D, Bartsch R
Obstet Gynecol 2013 Feb;121(2 Pt 1):337-343. doi: 10.1097/AOG.0b013e31827c5822. PMID: 23344284

See all (18)

Prognosis

Successful neoadjuvant chemotherapy plus sintilimab for locally advanced cervical cancer: case series and review of the literature.

Liu L, Deng X, Guo S, Yang S
Diagn Pathol 2023 Sep 26;18(1):107. doi: 10.1186/s13000-023-01394-w. PMID: 37752528 Free PMC Article

Hypoxic gastric cancer-derived exosomes promote progression and metastasis via MiR-301a-3p/PHD3/HIF-1α positive feedback loop.

Xia X, Wang S, Ni B, Xing S, Cao H, Zhang Z, Yu F, Zhao E, Zhao G
Oncogene 2020 Sep;39(39):6231-6244. Epub 2020 Aug 21 doi: 10.1038/s41388-020-01425-6. PMID: 32826951

Pathology of colorectal cancer.

Ponz de Leon M, Di Gregorio C
Dig Liver Dis 2001 May;33(4):372-88. doi: 10.1016/s1590-8658(01)80095-5. PMID: 11432519

New elements for an updated classification of the carcinomas of the stomach.

Carneiro F, Seixas M, Sobrinho-Simões M
Pathol Res Pract 1995 Jul;191(6):571-84. doi: 10.1016/S0344-0338(11)80878-2. PMID: 7479380

A comparative study of canine and human breast cancer.

Owen LN
Invest Cell Pathol 1979 Oct-Dec;2(4):257-75. PMID: 396282

See all (27)

Clinical prediction guides

Successful neoadjuvant chemotherapy plus sintilimab for locally advanced cervical cancer: case series and review of the literature.

Liu L, Deng X, Guo S, Yang S
Diagn Pathol 2023 Sep 26;18(1):107. doi: 10.1186/s13000-023-01394-w. PMID: 37752528 Free PMC Article

Hypoxic gastric cancer-derived exosomes promote progression and metastasis via MiR-301a-3p/PHD3/HIF-1α positive feedback loop.

Xia X, Wang S, Ni B, Xing S, Cao H, Zhang Z, Yu F, Zhao E, Zhao G
Oncogene 2020 Sep;39(39):6231-6244. Epub 2020 Aug 21 doi: 10.1038/s41388-020-01425-6. PMID: 32826951

Solid Microcystic Adnexal Carcinoma on the Thigh: An Unusual Location.

Diago A, Requena L, Traves V, Requena C
Am J Dermatopathol 2020 Feb;42(2):122-124. doi: 10.1097/DAD.0000000000001466. PMID: 31436574

Primary hepatic neuroendocrine tumors: multi-modal imaging features with pathological correlations.

Yang K, Cheng YS, Yang JJ, Jiang X, Guo JX
Cancer Imaging 2017 Jul 6;17(1):20. doi: 10.1186/s40644-017-0120-x. PMID: 28683830 Free PMC Article

Small bowel metastases in non-small cell lung cancer.

Stenbygaard LE, Sørensen JB
Lung Cancer 1999 Nov;26(2):95-101. doi: 10.1016/s0169-5002(99)00075-6. PMID: 10568680

See all (26)

Recent systematic reviews

The Use of Contrast-Enhanced Sonography for Therapy Monitoring of Metastatic Lymph Nodes: A Systematic Review.

Rink M, Jung EM, Künzel J
Curr Oncol 2023 Jul 16;30(7):6734-6743. doi: 10.3390/curroncol30070494. PMID: 37504354 Free PMC Article

Platinum derivatives during pregnancy in cervical cancer: a systematic review and meta-analysis.

Zagouri F, Sergentanis TN, Chrysikos D, Bartsch R
Obstet Gynecol 2013 Feb;121(2 Pt 1):337-343. doi: 10.1097/AOG.0b013e31827c5822. PMID: 23344284

See all (2)

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Solid Carcinoma

Definition

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

Supplemental Content

Table of contents

Practice guidelines

Related information

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