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Increased level of platelet-activating factor

MedGen UID:
892870
Concept ID:
C4073143
Finding
Synonym: Increased level of PAF
 
HPO: HP:0040178

Term Hierarchy

Conditions with this feature

Platelet-activating factor acetylhydrolase deficiency
MedGen UID:
481945
Concept ID:
C3280315
Disease or Syndrome
Reduced level of platelet-activating factor acetylhydrolase.

Professional guidelines

PubMed

Soleman J, Nocera F, Mariani L
Swiss Med Wkly 2017;147:w14398. Epub 2017 Jan 17 doi: 10.57187/smw.2017.14398. PMID: 28102879
Warkentin TE, Greinacher A
Curr Opin Hematol 2016 Sep;23(5):462-70. doi: 10.1097/MOH.0000000000000273. PMID: 27380556
Nettis E, Delle Donne P, Di Leo E, Calogiuri GF, Ferrannini A, Vacca A
Expert Opin Pharmacother 2013 Sep;14(13):1807-13. Epub 2013 Jun 28 doi: 10.1517/14656566.2013.813481. PMID: 23806068

Recent clinical studies

Etiology

Nilforoushzadeh MA, Heidari N, Heidari A, Ghane Y, Lotfi Z, Jaffary F, Najar Nobari M, Najar Nobari N
Int Immunopharmacol 2024 Apr 20;131:111827. Epub 2024 Mar 10 doi: 10.1016/j.intimp.2024.111827. PMID: 38460303
Xiang M, Wu X, Jing H, Liu L, Wang C, Wang Y, Novakovic VA, Shi J
Front Immunol 2022;13:955654. Epub 2022 Sep 28 doi: 10.3389/fimmu.2022.955654. PMID: 36248790Free PMC Article
Jansen MPB, Florquin S, Roelofs JJTH
Nat Rev Nephrol 2018 Jul;14(7):457-471. doi: 10.1038/s41581-018-0015-5. PMID: 29760447
Warkentin TE, Greinacher A
Curr Opin Hematol 2016 Sep;23(5):462-70. doi: 10.1097/MOH.0000000000000273. PMID: 27380556
Gallagher KT, Bernstein B
Curr Opin Rheumatol 1999 Sep;11(5):372-6. doi: 10.1097/00002281-199909000-00008. PMID: 10503657

Diagnosis

Li F, Xu T, Chen P, Sun R, Li C, Zhao X, Ou J, Li J, Liu T, Zeng M, Zheng W, Lin Y, Yang L, Li Z, Chen H, Zhang Q
Int J Biol Sci 2022;18(15):5858-5872. Epub 2022 Sep 24 doi: 10.7150/ijbs.76162. PMID: 36263165Free PMC Article
Raheem SG
Cell Mol Biol (Noisy-le-grand) 2021 Nov 25;67(3):1-4. doi: 10.14715/cmb/2021.67.3.1. PMID: 34933739
Warkentin TE
Int J Lab Hematol 2019 May;41 Suppl 1:15-25. doi: 10.1111/ijlh.12993. PMID: 31069988
Warkentin TE, Greinacher A
Curr Opin Hematol 2016 Sep;23(5):462-70. doi: 10.1097/MOH.0000000000000273. PMID: 27380556
Gallagher KT, Bernstein B
Curr Opin Rheumatol 1999 Sep;11(5):372-6. doi: 10.1097/00002281-199909000-00008. PMID: 10503657

Therapy

Schönborn L, Greinacher A
Semin Hematol 2022 Apr;59(2):108-114. Epub 2022 Mar 7 doi: 10.1053/j.seminhematol.2022.03.001. PMID: 35512899Free PMC Article
Warkentin TE
Int J Lab Hematol 2019 May;41 Suppl 1:15-25. doi: 10.1111/ijlh.12993. PMID: 31069988
Warkentin TE, Greinacher A
Curr Opin Hematol 2016 Sep;23(5):462-70. doi: 10.1097/MOH.0000000000000273. PMID: 27380556
Gallagher KT, Bernstein B
Curr Opin Rheumatol 1999 Sep;11(5):372-6. doi: 10.1097/00002281-199909000-00008. PMID: 10503657
Kingsnorth AN
Scand J Gastroenterol Suppl 1996;219:28-31. doi: 10.3109/00365529609104996. PMID: 8865468

Prognosis

Wahid HH, Anahar FN, Isahak NH, Mohd Zoharodzi J, Mohammad Khoiri SNL, Mohamad Zainal NH, Kamarudin N, Ismail H, Mustafa Mahmud MIA
Am J Pathol 2024 Jun;194(6):862-878. Epub 2024 Feb 24 doi: 10.1016/j.ajpath.2024.01.018. PMID: 38403163
de Carvalho JCS, da Silva-Neto PV, Toro DM, Fuzo CA, Nardini V, Pimentel VE, Pérez MM, Fraga-Silva TFC, Oliveira CNS, Degiovani AM, Ostini FM, Feitosa MR, Parra RS, da Rocha JJR, Feres O, Vilar FC, Gaspar GG, Santos IKFM, Fernandes APM, Maruyama SR, Russo EMS, Bonato VLD, Cardoso CRB, Dias-Baruffi M, Faccioli LH, Sorgi CA, On Behalf Of The ImmunoCovid Study Group
Viruses 2023 Feb 19;15(2) doi: 10.3390/v15020573. PMID: 36851787Free PMC Article
Raheem SG
Cell Mol Biol (Noisy-le-grand) 2021 Nov 25;67(3):1-4. doi: 10.14715/cmb/2021.67.3.1. PMID: 34933739
Soleman J, Nocera F, Mariani L
Swiss Med Wkly 2017;147:w14398. Epub 2017 Jan 17 doi: 10.57187/smw.2017.14398. PMID: 28102879
Kox WJ, Volk T, Kox SN, Volk HD
Intensive Care Med 2000;26 Suppl 1:S124-8. doi: 10.1007/s001340051129. PMID: 10786969

Clinical prediction guides

Wahid HH, Anahar FN, Isahak NH, Mohd Zoharodzi J, Mohammad Khoiri SNL, Mohamad Zainal NH, Kamarudin N, Ismail H, Mustafa Mahmud MIA
Am J Pathol 2024 Jun;194(6):862-878. Epub 2024 Feb 24 doi: 10.1016/j.ajpath.2024.01.018. PMID: 38403163
Xiang M, Wu X, Jing H, Liu L, Wang C, Wang Y, Novakovic VA, Shi J
Front Immunol 2022;13:955654. Epub 2022 Sep 28 doi: 10.3389/fimmu.2022.955654. PMID: 36248790Free PMC Article
Winkler M, Staniczek T, Kürschner SW, Schmid CD, Schönhaber H, Cordero J, Kessler L, Mathes A, Sticht C, Neßling M, Uvarovskii A, Anders S, Zhang XJ, von Figura G, Hartmann D, Mogler C, Dobreva G, Schledzewski K, Géraud C, Koch PS, Goerdt S
J Hepatol 2021 Feb;74(2):380-393. Epub 2020 Sep 9 doi: 10.1016/j.jhep.2020.08.033. PMID: 32916216
Soleman J, Nocera F, Mariani L
Swiss Med Wkly 2017;147:w14398. Epub 2017 Jan 17 doi: 10.57187/smw.2017.14398. PMID: 28102879
Kingsnorth AN
Scand J Gastroenterol Suppl 1996;219:28-31. doi: 10.3109/00365529609104996. PMID: 8865468

Recent systematic reviews

Wang Y, Wang H, Zhang C, Zhang C, Yang H, Gao R, Tong Z
Crit Care 2019 Feb 12;23(1):43. doi: 10.1186/s13054-019-2336-6. PMID: 30755248Free PMC Article
Soleman J, Nocera F, Mariani L
Swiss Med Wkly 2017;147:w14398. Epub 2017 Jan 17 doi: 10.57187/smw.2017.14398. PMID: 28102879
Nettis E, Delle Donne P, Di Leo E, Calogiuri GF, Ferrannini A, Vacca A
Expert Opin Pharmacother 2013 Sep;14(13):1807-13. Epub 2013 Jun 28 doi: 10.1517/14656566.2013.813481. PMID: 23806068

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