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Increased level of platelet-activating factor

MedGen UID:
892870
Concept ID:
C4073143
Finding
Synonym: Increased level of PAF
 
HPO: HP:0040178

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased level of platelet-activating factor

Conditions with this feature

Platelet-activating factor acetylhydrolase deficiency
MedGen UID:
481945
Concept ID:
C3280315
Disease or Syndrome
Reduced level of platelet-activating factor acetylhydrolase.

Professional guidelines

PubMed

Soleman J, Nocera F, Mariani L
Swiss Med Wkly 2017;147:w14398. Epub 2017 Jan 17 doi: 10.57187/smw.2017.14398. PMID: 28102879
Warkentin TE, Greinacher A
Curr Opin Hematol 2016 Sep;23(5):462-70. doi: 10.1097/MOH.0000000000000273. PMID: 27380556
Nettis E, Delle Donne P, Di Leo E, Calogiuri GF, Ferrannini A, Vacca A
Expert Opin Pharmacother 2013 Sep;14(13):1807-13. Epub 2013 Jun 28 doi: 10.1517/14656566.2013.813481. PMID: 23806068

Recent clinical studies

Etiology

Xiang M, Wu X, Jing H, Liu L, Wang C, Wang Y, Novakovic VA, Shi J
Front Immunol 2022;13:955654. Epub 2022 Sep 28 doi: 10.3389/fimmu.2022.955654. PMID: 36248790Free PMC Article
Jansen MPB, Florquin S, Roelofs JJTH
Nat Rev Nephrol 2018 Jul;14(7):457-471. doi: 10.1038/s41581-018-0015-5. PMID: 29760447
Warkentin TE, Greinacher A
Curr Opin Hematol 2016 Sep;23(5):462-70. doi: 10.1097/MOH.0000000000000273. PMID: 27380556
Stafforini DM
Cardiovasc Drugs Ther 2009 Feb;23(1):73-83. Epub 2008 Oct 24 doi: 10.1007/s10557-008-6133-8. PMID: 18949548
Gallagher KT, Bernstein B
Curr Opin Rheumatol 1999 Sep;11(5):372-6. doi: 10.1097/00002281-199909000-00008. PMID: 10503657

Diagnosis

Li F, Xu T, Chen P, Sun R, Li C, Zhao X, Ou J, Li J, Liu T, Zeng M, Zheng W, Lin Y, Yang L, Li Z, Chen H, Zhang Q
Int J Biol Sci 2022;18(15):5858-5872. Epub 2022 Sep 24 doi: 10.7150/ijbs.76162. PMID: 36263165Free PMC Article
Warkentin TE
Int J Lab Hematol 2019 May;41 Suppl 1:15-25. doi: 10.1111/ijlh.12993. PMID: 31069988
Warkentin TE, Greinacher A
Curr Opin Hematol 2016 Sep;23(5):462-70. doi: 10.1097/MOH.0000000000000273. PMID: 27380556
Prasad K
J Cardiovasc Pharmacol 2009 Nov;54(5):369-77. doi: 10.1097/FJC.0b013e3181af04e5. PMID: 19568181
Gallagher KT, Bernstein B
Curr Opin Rheumatol 1999 Sep;11(5):372-6. doi: 10.1097/00002281-199909000-00008. PMID: 10503657

Therapy

Schönborn L, Greinacher A
Semin Hematol 2022 Apr;59(2):108-114. Epub 2022 Mar 7 doi: 10.1053/j.seminhematol.2022.03.001. PMID: 35512899Free PMC Article
Warkentin TE
Int J Lab Hematol 2019 May;41 Suppl 1:15-25. doi: 10.1111/ijlh.12993. PMID: 31069988
Warkentin TE, Greinacher A
Curr Opin Hematol 2016 Sep;23(5):462-70. doi: 10.1097/MOH.0000000000000273. PMID: 27380556
Gallagher KT, Bernstein B
Curr Opin Rheumatol 1999 Sep;11(5):372-6. doi: 10.1097/00002281-199909000-00008. PMID: 10503657
Kingsnorth AN
Scand J Gastroenterol Suppl 1996;219:28-31. doi: 10.3109/00365529609104996. PMID: 8865468

Prognosis

Tang S, Ni J, Chen B, Sun F, Huang J, Ni S, Tang Z
BMC Cancer 2022 May 9;22(1):525. doi: 10.1186/s12885-022-09617-x. PMID: 35534807Free PMC Article
Darwish I, Fareed J, Brailovsky Y, Hoppensteadt D, Slajus B, Bontekoe E, De Stefano F, Reed T, Darki A
Clin Appl Thromb Hemost 2022 Jan-Dec;28:10760296211064898. doi: 10.1177/10760296211064898. PMID: 35043658Free PMC Article
Raheem SG
Cell Mol Biol (Noisy-le-grand) 2021 Nov 25;67(3):1-4. doi: 10.14715/cmb/2021.67.3.1. PMID: 34933739
Soleman J, Nocera F, Mariani L
Swiss Med Wkly 2017;147:w14398. Epub 2017 Jan 17 doi: 10.57187/smw.2017.14398. PMID: 28102879
Kox WJ, Volk T, Kox SN, Volk HD
Intensive Care Med 2000;26 Suppl 1:S124-8. doi: 10.1007/s001340051129. PMID: 10786969

Clinical prediction guides

Xiang M, Wu X, Jing H, Liu L, Wang C, Wang Y, Novakovic VA, Shi J
Front Immunol 2022;13:955654. Epub 2022 Sep 28 doi: 10.3389/fimmu.2022.955654. PMID: 36248790Free PMC Article
Winkler M, Staniczek T, Kürschner SW, Schmid CD, Schönhaber H, Cordero J, Kessler L, Mathes A, Sticht C, Neßling M, Uvarovskii A, Anders S, Zhang XJ, von Figura G, Hartmann D, Mogler C, Dobreva G, Schledzewski K, Géraud C, Koch PS, Goerdt S
J Hepatol 2021 Feb;74(2):380-393. Epub 2020 Sep 9 doi: 10.1016/j.jhep.2020.08.033. PMID: 32916216
Soleman J, Nocera F, Mariani L
Swiss Med Wkly 2017;147:w14398. Epub 2017 Jan 17 doi: 10.57187/smw.2017.14398. PMID: 28102879
Stafforini DM
Cardiovasc Drugs Ther 2009 Feb;23(1):73-83. Epub 2008 Oct 24 doi: 10.1007/s10557-008-6133-8. PMID: 18949548
Kingsnorth AN
Scand J Gastroenterol Suppl 1996;219:28-31. doi: 10.3109/00365529609104996. PMID: 8865468

Recent systematic reviews

Wang Y, Wang H, Zhang C, Zhang C, Yang H, Gao R, Tong Z
Crit Care 2019 Feb 12;23(1):43. doi: 10.1186/s13054-019-2336-6. PMID: 30755248Free PMC Article
Soleman J, Nocera F, Mariani L
Swiss Med Wkly 2017;147:w14398. Epub 2017 Jan 17 doi: 10.57187/smw.2017.14398. PMID: 28102879
Nettis E, Delle Donne P, Di Leo E, Calogiuri GF, Ferrannini A, Vacca A
Expert Opin Pharmacother 2013 Sep;14(13):1807-13. Epub 2013 Jun 28 doi: 10.1517/14656566.2013.813481. PMID: 23806068

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