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Abnormal magnesium concentration

MedGen UID:
893133
•Concept ID:
C4025274
•
Finding
Synonyms: Abnormal magnesium metabolism; Abnormal Mg concentration; Abnormality of magnesium homeostasis
 
HPO: HP:0004921

Definition

An abnormality of magnesium ion homeostasis. [from HPO]

Conditions with this feature

Familial hypokalemic alkalosis, Gullner type
MedGen UID:
78677
•Concept ID:
C0268444
•
Disease or Syndrome
See: Condition Record
Familial hypokalemic alkalosis, Gullner type

Professional guidelines

PubMed

Pharmacological treatment of acquired QT prolongation and torsades de pointes.
Thomas SH, Behr ER
Br J Clin Pharmacol 2016 Mar;81(3):420-7. Epub 2015 Oct 26 doi: 10.1111/bcp.12726. PMID: 26183037Free PMC Article
Nutritional factors in the prevention and management of coronary artery disease and heart failure.
Das UN
Nutrition 2015 Feb;31(2):283-91. Epub 2014 Sep 4 doi: 10.1016/j.nut.2014.08.011. PMID: 25592005
Nutritional strategies in the prevention and treatment of metabolic syndrome.
Feldeisen SE, Tucker KL
Appl Physiol Nutr Metab 2007 Feb;32(1):46-60. doi: 10.1139/h06-101. PMID: 17332784

Recent clinical studies

Etiology

Prevalence of Dysnatremia in Pulmonary Tuberculosis.
Singh B, Hayagreev VN, Kk S, Parashuram
J Assoc Physicians India 2022 Apr;70(4):11-12. PMID: 35443463
Gestational hypercalcemia: Prevalence and biochemical profile.
Schoenmakers I, Piec I, Baban S, Bärebring L, Green D, Washbourne CJ, Tang JCY, Fraser WD, Augustin H
J Steroid Biochem Mol Biol 2020 May;199:105611. Epub 2020 Jan 30 doi: 10.1016/j.jsbmb.2020.105611. PMID: 32007562
Acid-base and electrolyte disorders associated with the use of antidiabetic drugs.
Filippatos T, Tzavella E, Rizos C, Elisaf M, Liamis G
Expert Opin Drug Saf 2017 Oct;16(10):1121-1132. Epub 2017 Aug 4 doi: 10.1080/14740338.2017.1361400. PMID: 28748724
Pharmacological treatment of acquired QT prolongation and torsades de pointes.
Thomas SH, Behr ER
Br J Clin Pharmacol 2016 Mar;81(3):420-7. Epub 2015 Oct 26 doi: 10.1111/bcp.12726. PMID: 26183037Free PMC Article
Influence of mineral and vitamin supplements on pregnancy outcome.
Hovdenak N, Haram K
Eur J Obstet Gynecol Reprod Biol 2012 Oct;164(2):127-32. Epub 2012 Jul 6 doi: 10.1016/j.ejogrb.2012.06.020. PMID: 22771225

Diagnosis

Prevalence of Dysnatremia in Pulmonary Tuberculosis.
Singh B, Hayagreev VN, Kk S, Parashuram
J Assoc Physicians India 2022 Apr;70(4):11-12. PMID: 35443463
Cardiorenal syndrome in thalassemia patients.
Makmettakul S, Tantiworawit A, Phrommintikul A, Piriyakhuntorn P, Rattanathammethee T, Hantrakool S, Chai-Adisaksopha C, Rattarittamrong E, Norasetthada L, Fanhchaksai K, Charoenkwan P, Lekawanvijit S
BMC Nephrol 2020 Aug 3;21(1):325. doi: 10.1186/s12882-020-01990-8. PMID: 32746879Free PMC Article
Gestational hypercalcemia: Prevalence and biochemical profile.
Schoenmakers I, Piec I, Baban S, Bärebring L, Green D, Washbourne CJ, Tang JCY, Fraser WD, Augustin H
J Steroid Biochem Mol Biol 2020 May;199:105611. Epub 2020 Jan 30 doi: 10.1016/j.jsbmb.2020.105611. PMID: 32007562
Magnesium and phosphorus.
Weisinger JR, Bellorín-Font E
Lancet 1998 Aug 1;352(9125):391-6. doi: 10.1016/S0140-6736(97)10535-9. PMID: 9717944
Abnormal renal magnesium handling.
Sutton RA, Domrongkitchaiporn S
Miner Electrolyte Metab 1993;19(4-5):232-40. PMID: 8264509

Therapy

Gestational hypercalcemia: Prevalence and biochemical profile.
Schoenmakers I, Piec I, Baban S, Bärebring L, Green D, Washbourne CJ, Tang JCY, Fraser WD, Augustin H
J Steroid Biochem Mol Biol 2020 May;199:105611. Epub 2020 Jan 30 doi: 10.1016/j.jsbmb.2020.105611. PMID: 32007562
Pharmacological treatment of acquired QT prolongation and torsades de pointes.
Thomas SH, Behr ER
Br J Clin Pharmacol 2016 Mar;81(3):420-7. Epub 2015 Oct 26 doi: 10.1111/bcp.12726. PMID: 26183037Free PMC Article
Influence of mineral and vitamin supplements on pregnancy outcome.
Hovdenak N, Haram K
Eur J Obstet Gynecol Reprod Biol 2012 Oct;164(2):127-32. Epub 2012 Jul 6 doi: 10.1016/j.ejogrb.2012.06.020. PMID: 22771225
Magnesium and diabetes: a review.
White JR Jr, Campbell RK
Ann Pharmacother 1993 Jun;27(6):775-80. doi: 10.1177/106002809302700619. PMID: 8329802
Amphotericin B nephrotoxicity.
Sabra R, Branch RA
Drug Saf 1990 Mar-Apr;5(2):94-108. doi: 10.2165/00002018-199005020-00003. PMID: 2182052

Prognosis

The association between abnormal serum magnesium levels and prognosis of elderly patients with community-acquired pneumonia.
Wang SQ, Lu DX, Zhang JD, Wang ZW, Li XW, Ma CM
Magnes Res 2021 Nov 1;34(4):159-165. doi: 10.1684/mrh.2022.0493. PMID: 35212628
Magnesium and phosphorus.
Weisinger JR, Bellorín-Font E
Lancet 1998 Aug 1;352(9125):391-6. doi: 10.1016/S0140-6736(97)10535-9. PMID: 9717944
Significance of magnesium in congestive heart failure.
Douban S, Brodsky MA, Whang DD, Whang R
Am Heart J 1996 Sep;132(3):664-71. doi: 10.1016/s0002-8703(96)90253-7. PMID: 8800040
Recognition and management of digitalis toxicity.
Kelly RA, Smith TW
Am J Cardiol 1992 Jun 4;69(18):108G-118G; disc. 118G-119G. doi: 10.1016/0002-9149(92)91259-7. PMID: 1626485
Current concepts of the pathogenesis and management of diabetic ketoacidosis (DKA).
Yan P, Cheah JS, Thai AC, Yeo PP
Ann Acad Med Singap 1983 Oct;12(4):596-605. PMID: 6331271

Clinical prediction guides

Magnesium-DNA interactions and the possible relation of magnesium to carcinogenesis. Irradiation and free radicals.
Anastassopoulou J, Theophanides T
Crit Rev Oncol Hematol 2002 Apr;42(1):79-91. doi: 10.1016/s1040-8428(02)00006-9. PMID: 11923070
Magnesium and phosphorus.
Weisinger JR, Bellorín-Font E
Lancet 1998 Aug 1;352(9125):391-6. doi: 10.1016/S0140-6736(97)10535-9. PMID: 9717944
Magnesium homeostasis and clinical disorders of magnesium deficiency.
Whang R, Hampton EM, Whang DD
Ann Pharmacother 1994 Feb;28(2):220-6. doi: 10.1177/106002809402800213. PMID: 8173141
Magnesium and diabetes: a review.
White JR Jr, Campbell RK
Ann Pharmacother 1993 Jun;27(6):775-80. doi: 10.1177/106002809302700619. PMID: 8329802
Amphotericin B nephrotoxicity.
Sabra R, Branch RA
Drug Saf 1990 Mar-Apr;5(2):94-108. doi: 10.2165/00002018-199005020-00003. PMID: 2182052

Recent systematic reviews

Micronutrient Status in Adult Crohn's Disease during Clinical Remission: A Systematic Review.
McDonnell M, Sartain S, Westoby C, Katarachia V, Wootton SA, Cummings JRF
Nutrients 2023 Nov 14;15(22) doi: 10.3390/nu15224777. PMID: 38004171Free PMC Article
Hypomagnesemia in intestinal lymphangiectasia: a case report and review of the literature.
Feng H, Zou L, Zhai X, Zhang S, Li J
BMC Gastroenterol 2022 May 15;22(1):246. doi: 10.1186/s12876-022-02318-6. PMID: 35570283Free PMC Article
Crosstalk of Magnesium and Serum Lipids in Dyslipidemia and Associated Disorders: A Systematic Review.
Găman MA, Dobrică EC, Cozma MA, Antonie NI, Stănescu AMA, Găman AM, Diaconu CC
Nutrients 2021 Apr 22;13(5) doi: 10.3390/nu13051411. PMID: 33922341Free PMC Article

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