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Abnormal blood cation concentration

MedGen UID:
869223
•Concept ID:
C4023646
•
Finding
Synonym: Abnormality of cation homeostasis
 
HPO: HP:0010929

Definition

An abnormality of cation homeostasis. [from HPO]

Professional guidelines

PubMed

Diagnosis and Management of Disorders of Body Tonicity-Hyponatremia and Hypernatremia: Core Curriculum 2020.
Seay NW, Lehrich RW, Greenberg A
Am J Kidney Dis 2020 Feb;75(2):272-286. Epub 2019 Oct 10 doi: 10.1053/j.ajkd.2019.07.014. PMID: 31606238
▼Patiromer for the management of hyperkalaemia.
Drug Ther Bull 2018 Jan;56(1):6-9. doi: 10.1136/dtb.2018.1.0575. PMID: 29326277
Effects of cetiedil on monovalent cation permeability in the erythrocyte: an explanation for the efficacy of cetiedil in the treatment of sickle cell anemia.
Berkowitz LR, Orringer EP
Blood Cells 1982;8(2):283-8. PMID: 7159752

Recent clinical studies

Etiology

Use of the Urine-to-Plasma Urea Ratio to Predict ADPKD Progression.
Heida JE, Gansevoort RT, Messchendorp AL, Meijer E, Casteleijn NF, Boertien WE, Zittema D; DIPAK Consortium
Clin J Am Soc Nephrol 2021 Feb 8;16(2):204-212. Epub 2021 Jan 27 doi: 10.2215/CJN.10470620. PMID: 33504546Free PMC Article
Submission for Special Issue: The Role of Platelet Activation in the Pathophysiology of HIV, Tuberculosis, and Pneumococcal Disease. Bedaquiline Suppresses ADP-Mediated Activation of Human Platelets In Vitro via Interference With Phosphatidylinositol 3-Kinase.
Tintinger GR, Theron AJ, Steel HC, Cholo MC, Nel JG, Feldman C, Anderson R
Front Immunol 2020;11:621148. Epub 2021 Feb 26 doi: 10.3389/fimmu.2020.621148. PMID: 33717055Free PMC Article
Reduced hippocampal glutamate-glutamine levels in irritable bowel syndrome: preliminary findings using magnetic resonance spectroscopy.
Niddam DM, Tsai SY, Lu CL, Ko CW, Hsieh JC
Am J Gastroenterol 2011 Aug;106(8):1503-11. Epub 2011 Apr 19 doi: 10.1038/ajg.2011.120. PMID: 21502999
Clinical approach to renal tubular acidosis in adult patients.
Reddy P
Int J Clin Pract 2011 Mar;65(3):350-60. doi: 10.1111/j.1742-1241.2009.02311.x. PMID: 21314872
The presence of eosinophil cationic protein in middle ear effusion.
Hurst DS, Venge P
Otolaryngol Head Neck Surg 1993 Jun;108(6):711-22. doi: 10.1177/019459989310800614. PMID: 8516010

Diagnosis

Use of the Urine-to-Plasma Urea Ratio to Predict ADPKD Progression.
Heida JE, Gansevoort RT, Messchendorp AL, Meijer E, Casteleijn NF, Boertien WE, Zittema D; DIPAK Consortium
Clin J Am Soc Nephrol 2021 Feb 8;16(2):204-212. Epub 2021 Jan 27 doi: 10.2215/CJN.10470620. PMID: 33504546Free PMC Article
Diagnosis and Management of Disorders of Body Tonicity-Hyponatremia and Hypernatremia: Core Curriculum 2020.
Seay NW, Lehrich RW, Greenberg A
Am J Kidney Dis 2020 Feb;75(2):272-286. Epub 2019 Oct 10 doi: 10.1053/j.ajkd.2019.07.014. PMID: 31606238
A non-electrolyte haemolysis assay for diagnosis and prognosis of sickle cell disease.
Milligan C, Rees DC, Ellory JC, Osei A, Browning JA, Hannemann A, Gibson JS
J Physiol 2013 Mar 15;591(6):1463-74. Epub 2013 Jan 7 doi: 10.1113/jphysiol.2012.246579. PMID: 23297308Free PMC Article
Clinical approach to renal tubular acidosis in adult patients.
Reddy P
Int J Clin Pract 2011 Mar;65(3):350-60. doi: 10.1111/j.1742-1241.2009.02311.x. PMID: 21314872
Psychiatric aspects of parathyroid disease.
Velasco PJ, Manshadi M, Breen K, Lippmann S
Psychosomatics 1999 Nov-Dec;40(6):486-90. doi: 10.1016/s0033-3182(99)71186-2. PMID: 10581976

Therapy

Submission for Special Issue: The Role of Platelet Activation in the Pathophysiology of HIV, Tuberculosis, and Pneumococcal Disease. Bedaquiline Suppresses ADP-Mediated Activation of Human Platelets In Vitro via Interference With Phosphatidylinositol 3-Kinase.
Tintinger GR, Theron AJ, Steel HC, Cholo MC, Nel JG, Feldman C, Anderson R
Front Immunol 2020;11:621148. Epub 2021 Feb 26 doi: 10.3389/fimmu.2020.621148. PMID: 33717055Free PMC Article
▼Patiromer for the management of hyperkalaemia.
Drug Ther Bull 2018 Jan;56(1):6-9. doi: 10.1136/dtb.2018.1.0575. PMID: 29326277
Clinical approach to renal tubular acidosis in adult patients.
Reddy P
Int J Clin Pract 2011 Mar;65(3):350-60. doi: 10.1111/j.1742-1241.2009.02311.x. PMID: 21314872
Antisickling effects of 2,3-diphosphoglycerate depletion.
Poillon WN, Kim BC, Labotka RJ, Hicks CU, Kark JA
Blood 1995 Jun 1;85(11):3289-96. PMID: 7756662
Human epileptic brain Na, K ATPase activity and phenytoin concentrations.
Rapport RL 2nd, Harris AB, Friel PN, Ojemann GA
Arch Neurol 1975 Aug;32(8):549-54. doi: 10.1001/archneur.1975.00490500069008. PMID: 125576

Prognosis

Differentiation between sepsis survivors and sepsis non-survivors through blood serum metabolomics: A proton nuclear magnetic resonance spectroscopy (NMR) study.
Naveen Kumar MS, Gupta G, Kumar V, Jagannathan NR, Sinha S, Mewar S, Kumar P
Magn Reson Imaging 2022 Jun;89:49-57. Epub 2022 Feb 14 doi: 10.1016/j.mri.2022.02.003. PMID: 35176448
Use of the Urine-to-Plasma Urea Ratio to Predict ADPKD Progression.
Heida JE, Gansevoort RT, Messchendorp AL, Meijer E, Casteleijn NF, Boertien WE, Zittema D; DIPAK Consortium
Clin J Am Soc Nephrol 2021 Feb 8;16(2):204-212. Epub 2021 Jan 27 doi: 10.2215/CJN.10470620. PMID: 33504546Free PMC Article
A non-electrolyte haemolysis assay for diagnosis and prognosis of sickle cell disease.
Milligan C, Rees DC, Ellory JC, Osei A, Browning JA, Hannemann A, Gibson JS
J Physiol 2013 Mar 15;591(6):1463-74. Epub 2013 Jan 7 doi: 10.1113/jphysiol.2012.246579. PMID: 23297308Free PMC Article
Chemical mediators of the muscle ergoreflex in chronic heart failure: a putative role for prostaglandins in reflex ventilatory control.
Scott AC, Wensel R, Davos CH, Kemp M, Kaczmarek A, Hooper J, Coats AJ, Piepoli MF
Circulation 2002 Jul 9;106(2):214-20. doi: 10.1161/01.cir.0000021603.36744.5e. PMID: 12105161
Predictive value of derived calcium figures based on the measurement of ionised calcium.
Gardner MD, Dryburgh FJ, Fyffe JA, Jenkins AS
Ann Clin Biochem 1981 Mar;18 (Pt 2):106-9. doi: 10.1177/000456328101800210. PMID: 7259068

Clinical prediction guides

Differentiation between sepsis survivors and sepsis non-survivors through blood serum metabolomics: A proton nuclear magnetic resonance spectroscopy (NMR) study.
Naveen Kumar MS, Gupta G, Kumar V, Jagannathan NR, Sinha S, Mewar S, Kumar P
Magn Reson Imaging 2022 Jun;89:49-57. Epub 2022 Feb 14 doi: 10.1016/j.mri.2022.02.003. PMID: 35176448
Use of the Urine-to-Plasma Urea Ratio to Predict ADPKD Progression.
Heida JE, Gansevoort RT, Messchendorp AL, Meijer E, Casteleijn NF, Boertien WE, Zittema D; DIPAK Consortium
Clin J Am Soc Nephrol 2021 Feb 8;16(2):204-212. Epub 2021 Jan 27 doi: 10.2215/CJN.10470620. PMID: 33504546Free PMC Article
Decreased serum osmolality promotes ductus arteriosus constriction.
Aoki R, Yokoyama U, Ichikawa Y, Taguri M, Kumagaya S, Ishiwata R, Yanai C, Fujita S, Umemura M, Fujita T, Okumura S, Sato M, Minamisawa S, Asou T, Masuda M, Iwasaki S, Nishimaki S, Seki K, Yokota S, Ishikawa Y
Cardiovasc Res 2014 Nov 1;104(2):326-36. Epub 2014 Sep 4 doi: 10.1093/cvr/cvu199. PMID: 25190043
Clinical approach to renal tubular acidosis in adult patients.
Reddy P
Int J Clin Pract 2011 Mar;65(3):350-60. doi: 10.1111/j.1742-1241.2009.02311.x. PMID: 21314872
Abnormal membrane protein of red blood cells in hereditary spherocytosis.
Jacob HS, Ruby A, Overland ES, Mazia D
J Clin Invest 1971 Sep;50(9):1800-5. doi: 10.1172/JCI106670. PMID: 5564386Free PMC Article

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