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Cervical Adenocarcinoma In Situ

MedGen UID:
91092
Concept ID:
C0346203
Neoplastic Process
Synonyms: Adenocarcinoma in situ of cervix; Adenocarcinoma in situ of Cervix; Adenocarcinoma in situ of Cervix Uteri; Adenocarcinoma in situ of the Cervix; Adenocarcinoma in situ of the Cervix Uteri; Adenocarcinoma in situ of the Uterine Cervix; Adenocarcinoma in situ of Uterine Cervix; AIS - Adenocarcinoma in situ of cervix; Cervical ACIS (adenocarcinoma in situ); Cervix Adenocarcinoma in situ; Cervix Uteri Adenocarcinoma in situ; Uterine Cervix Adenocarcinoma in situ
SNOMED CT: Cervical ACIS (adenocarcinoma in situ) (254890008); AIS - Adenocarcinoma in situ of cervix (254890008); Adenocarcinoma in situ of cervix (254890008)

Definition

Stage 0 includes: (Tis, N0, M0). Tis: Carcinoma in situ. N0: No regional lymph node metastasis. M0: No distant metastasis. FIGO no longer includes stage 0. (AJCC 7th ed.) [from NCI]

Term Hierarchy

Professional guidelines

PubMed

Zhang RC, Vue NC, Obasi LU, Vogel RI, Subramanian AT, Khalifa MA, Reddy BR, Erickson BK
J Low Genit Tract Dis 2021 Oct 1;25(4):267-269. doi: 10.1097/LGT.0000000000000618. PMID: 34265818Free PMC Article
Teoh D, Musa F, Salani R, Huh W, Jimenez E
Obstet Gynecol 2020 Apr;135(4):869-878. doi: 10.1097/AOG.0000000000003761. PMID: 32168211Free PMC Article
Bertrand M, Lickrish GM, Colgan TJ
Am J Obstet Gynecol 1987 Jul;157(1):21-5. doi: 10.1016/s0002-9378(87)80338-1. PMID: 3605256

Recent clinical studies

Etiology

Monti E, Somigliana E, Alberico D, Boero V, Iorio M, Di Loreto E, Dell'acqua A, Liverani CA
J Low Genit Tract Dis 2022 Oct 1;26(4):293-297. Epub 2022 Aug 3 doi: 10.1097/LGT.0000000000000688. PMID: 35917498
Sánchez-Cuerda C, Cuadra M, Gámir S, Lobo P, Elices M, Cabrera Y
Int J Gynaecol Obstet 2022 Jul;158(1):21-26. Epub 2021 Oct 23 doi: 10.1002/ijgo.13948. PMID: 34559882
Zhang RC, Vue NC, Obasi LU, Vogel RI, Subramanian AT, Khalifa MA, Reddy BR, Erickson BK
J Low Genit Tract Dis 2021 Oct 1;25(4):267-269. doi: 10.1097/LGT.0000000000000618. PMID: 34265818Free PMC Article
Teoh D, Musa F, Salani R, Huh W, Jimenez E
Obstet Gynecol 2020 Apr;135(4):869-878. doi: 10.1097/AOG.0000000000003761. PMID: 32168211Free PMC Article
Cleveland AA, Gargano JW, Park IU, Griffin MR, Niccolai LM, Powell M, Bennett NM, Saadeh K, Pemmaraju M, Higgins K, Ehlers S, Scahill M, Johnson Jones ML, Querec T, Markowitz LE, Unger ER; HPV-IMPACT Working Group
Int J Cancer 2020 Feb 1;146(3):810-818. Epub 2019 May 6 doi: 10.1002/ijc.32340. PMID: 30980692Free PMC Article

Diagnosis

Sánchez-Cuerda C, Cuadra M, Gámir S, Lobo P, Elices M, Cabrera Y
Int J Gynaecol Obstet 2022 Jul;158(1):21-26. Epub 2021 Oct 23 doi: 10.1002/ijgo.13948. PMID: 34559882
Nikolopoulos M, Athanasias P, Godfrey MAL, Nikolopoulos K, Maheshwari MK
Cytopathology 2021 Nov;32(6):751-757. Epub 2021 Jul 20 doi: 10.1111/cyt.13027. PMID: 34181788
Teoh D, Musa F, Salani R, Huh W, Jimenez E
Obstet Gynecol 2020 Apr;135(4):869-878. doi: 10.1097/AOG.0000000000003761. PMID: 32168211Free PMC Article
Cleveland AA, Gargano JW, Park IU, Griffin MR, Niccolai LM, Powell M, Bennett NM, Saadeh K, Pemmaraju M, Higgins K, Ehlers S, Scahill M, Johnson Jones ML, Querec T, Markowitz LE, Unger ER; HPV-IMPACT Working Group
Int J Cancer 2020 Feb 1;146(3):810-818. Epub 2019 May 6 doi: 10.1002/ijc.32340. PMID: 30980692Free PMC Article
Krivak TC, Rose GS, McBroom JW, Carlson JW, Winter WE 3rd, Kost ER
Obstet Gynecol Surv 2001 Sep;56(9):567-75. doi: 10.1097/00006254-200109000-00023. PMID: 11524622

Therapy

Liu J, Wang Y, Wan X, Zou J, Zhu Y, Lv W, Shen Y
J Gynecol Oncol 2023 Jan;34(1):e8. Epub 2022 Nov 15 doi: 10.3802/jgo.2023.34.e8. PMID: 36424703Free PMC Article
Cohen PA, Leung Y, Anderson L, van der Griend R, Chivers P, Bilic S, Bittinger S, Brand A, Bulsara MK, Codde J, Eva L, Farrell L, Harker D, Herbst U, Jeffares S, Loh D, McNally O, Mohan GR, Nicholson T, Powell A, Salfinger SG, Simcock B, Stewart C, Silvers J, Stockler MR, Sykes P, Stoyles P, Tan A, Tan AL, Wrede CDH
Gynecol Oncol 2020 Dec;159(3):623-629. Epub 2020 Oct 5 doi: 10.1016/j.ygyno.2020.09.053. PMID: 33032824
Cleveland AA, Gargano JW, Park IU, Griffin MR, Niccolai LM, Powell M, Bennett NM, Saadeh K, Pemmaraju M, Higgins K, Ehlers S, Scahill M, Johnson Jones ML, Querec T, Markowitz LE, Unger ER; HPV-IMPACT Working Group
Int J Cancer 2020 Feb 1;146(3):810-818. Epub 2019 May 6 doi: 10.1002/ijc.32340. PMID: 30980692Free PMC Article
Cohen PA, Brand A, Sykes P, Wrede DCH, McNally O, Eva L, Rao A, Campion M, Stockler M, Powell A, Codde J, Bulsara MK, Anderson L, Leung Y, Farrell L, Stoyles P
BMJ Open 2017 Aug 28;7(8):e017576. doi: 10.1136/bmjopen-2017-017576. PMID: 28851799Free PMC Article
Krivak TC, Retherford B, Voskuil S, Rose GS, Alagoz T
Gynecol Oncol 2000 May;77(2):334-5. doi: 10.1006/gyno.2000.5761. PMID: 10785491

Prognosis

Upadhyay Baskota S, Wang T, Zhao C
J Low Genit Tract Dis 2021 Jan 1;25(1):38-42. doi: 10.1097/LGT.0000000000000579. PMID: 33284146
Jones TE, Onisko A, Austin RM
Acta Cytol 2021;65(2):158-164. Epub 2020 Dec 1 doi: 10.1159/000511620. PMID: 33260179
Cleveland AA, Gargano JW, Park IU, Griffin MR, Niccolai LM, Powell M, Bennett NM, Saadeh K, Pemmaraju M, Higgins K, Ehlers S, Scahill M, Johnson Jones ML, Querec T, Markowitz LE, Unger ER; HPV-IMPACT Working Group
Int J Cancer 2020 Feb 1;146(3):810-818. Epub 2019 May 6 doi: 10.1002/ijc.32340. PMID: 30980692Free PMC Article
Munro A, Codde J, Spilsbury K, Steel N, Stewart CJ, Salfinger SG, Tan J, Mohan GR, Leung Y, Semmens JB, O'Leary P, Williams V, Cohen PA
Am J Obstet Gynecol 2017 Mar;216(3):272.e1-272.e7. Epub 2016 Nov 28 doi: 10.1016/j.ajog.2016.11.1044. PMID: 27908632
Krivak TC, Rose GS, McBroom JW, Carlson JW, Winter WE 3rd, Kost ER
Obstet Gynecol Surv 2001 Sep;56(9):567-75. doi: 10.1097/00006254-200109000-00023. PMID: 11524622

Clinical prediction guides

Upadhyay Baskota S, Wang T, Zhao C
J Low Genit Tract Dis 2021 Jan 1;25(1):38-42. doi: 10.1097/LGT.0000000000000579. PMID: 33284146
Jones TE, Onisko A, Austin RM
Acta Cytol 2021;65(2):158-164. Epub 2020 Dec 1 doi: 10.1159/000511620. PMID: 33260179
Smedts F, Ramaekers FC, Hopman AH
Int J Gynecol Pathol 2010 Jul;29(4):378-85. doi: 10.1097/PGP.0b013e3181cd3175. PMID: 20567153
Krivak TC, Rose GS, McBroom JW, Carlson JW, Winter WE 3rd, Kost ER
Obstet Gynecol Surv 2001 Sep;56(9):567-75. doi: 10.1097/00006254-200109000-00023. PMID: 11524622
Hopkins MP, Roberts JA, Schmidt RW
Obstet Gynecol 1988 Jun;71(6 Pt 1):842-4. PMID: 3285263

Recent systematic reviews

Jiang Y, Chen C, Li L
PLoS One 2017;12(1):e0170587. Epub 2017 Jan 26 doi: 10.1371/journal.pone.0170587. PMID: 28125627Free PMC Article
Krivak TC, Rose GS, McBroom JW, Carlson JW, Winter WE 3rd, Kost ER
Obstet Gynecol Surv 2001 Sep;56(9):567-75. doi: 10.1097/00006254-200109000-00023. PMID: 11524622

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