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Metastatic Malignant Neoplasm in the Bone Marrow

MedGen UID:
91111
Concept ID:
C0346979
Neoplastic Process
Synonyms: Cancer metastatic to bone marrow; Metastases to the Bone Marrow; Metastasis to bone marrow; Metastasis to the Bone Marrow; Metastatic malignant neoplasm of bone marrow; Metastatic malignant neoplasm to bone marrow; Metastatic Malignant Neoplasm to the Bone Marrow; Metastatic Neoplasm to the Bone Marrow; Metastatic Tumor to the Bone Marrow; Secondary malignant neoplasm of bone marrow
SNOMED CT: Secondary malignant neoplasm of bone marrow (94217008); Metastatic malignant neoplasm to bone marrow (94217008); Cancer metastatic to bone marrow (94217008); Metastatic malignant neoplasm of bone marrow (94217008); Metastasis to bone marrow (94217008)

Definition

The spread of a malignant neoplasm from its original site of growth to the bone marrow. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Neoplasm in the Bone Marrow

Professional guidelines

PubMed

Farge D, Frere C, Connors JM, Khorana AA, Kakkar A, Ay C, Muñoz A, Brenner B, Prata PH, Brilhante D, Antic D, Casais P, Guillermo Esposito MC, Ikezoe T, Abutalib SA, Meillon-García LA, Bounameaux H, Pabinger I, Douketis J; International Initiative on Thrombosis and Cancer (ITAC) advisory panel
Lancet Oncol 2022 Jul;23(7):e334-e347. doi: 10.1016/S1470-2045(22)00160-7. PMID: 35772465Free PMC Article
Requena G, van den Bosch J, Akuthota P, Kovalszki A, Steinfeld J, Kwon N, Van Dyke MK
J Allergy Clin Immunol Pract 2022 Aug;10(8):2125-2134. Epub 2022 Apr 22 doi: 10.1016/j.jaip.2022.03.034. PMID: 35470096
Ullmann AJ, Aguado JM, Arikan-Akdagli S, Denning DW, Groll AH, Lagrou K, Lass-Flörl C, Lewis RE, Munoz P, Verweij PE, Warris A, Ader F, Akova M, Arendrup MC, Barnes RA, Beigelman-Aubry C, Blot S, Bouza E, Brüggemann RJM, Buchheidt D, Cadranel J, Castagnola E, Chakrabarti A, Cuenca-Estrella M, Dimopoulos G, Fortun J, Gangneux JP, Garbino J, Heinz WJ, Herbrecht R, Heussel CP, Kibbler CC, Klimko N, Kullberg BJ, Lange C, Lehrnbecher T, Löffler J, Lortholary O, Maertens J, Marchetti O, Meis JF, Pagano L, Ribaud P, Richardson M, Roilides E, Ruhnke M, Sanguinetti M, Sheppard DC, Sinkó J, Skiada A, Vehreschild MJGT, Viscoli C, Cornely OA
Clin Microbiol Infect 2018 May;24 Suppl 1:e1-e38. Epub 2018 Mar 12 doi: 10.1016/j.cmi.2018.01.002. PMID: 29544767

Recent clinical studies

Etiology

Shahait M, Abu-Hijlih R, Salamat A, Abou Heidar N, Sharaf B, Abuhijla F, Salah S
PLoS One 2022;17(7):e0270956. Epub 2022 Jul 21 doi: 10.1371/journal.pone.0270956. PMID: 35862364Free PMC Article
Mayhew V, Omokehinde T, Johnson RW
Cancer Rep (Hoboken) 2020 Feb;3(1):e1156. Epub 2019 Jan 29 doi: 10.1002/cnr2.1156. PMID: 32632400Free PMC Article
Tanaka TN, Bejar R
Blood 2019 Mar 7;133(10):1086-1095. Epub 2019 Jan 22 doi: 10.1182/blood-2018-10-844670. PMID: 30670443
Johnson RW, Sowder ME, Giaccia AJ
Curr Osteoporos Rep 2017 Aug;15(4):231-238. doi: 10.1007/s11914-017-0378-8. PMID: 28597139Free PMC Article
Khosravi A, Shahrabi S, Shahjahani M, Saki N
Cell Oncol (Dordr) 2015 Aug;38(4):253-63. Epub 2015 Jun 11 doi: 10.1007/s13402-015-0232-x. PMID: 26063518

Diagnosis

Ye X, Huang X, Fu X, Zhang X, Lin R, Zhang W, Zhang J, Lu Y
J Hematol Oncol 2023 May 3;16(1):46. doi: 10.1186/s13045-023-01442-4. PMID: 37138326Free PMC Article
Shahait M, Abu-Hijlih R, Salamat A, Abou Heidar N, Sharaf B, Abuhijla F, Salah S
PLoS One 2022;17(7):e0270956. Epub 2022 Jul 21 doi: 10.1371/journal.pone.0270956. PMID: 35862364Free PMC Article
Li Y, Cao S, Gaculenko A, Zhan Y, Bozec A, Chen X
Front Endocrinol (Lausanne) 2022;13:902033. Epub 2022 Jun 21 doi: 10.3389/fendo.2022.902033. PMID: 35800430Free PMC Article
Ferrer A, Roser CT, El-Far MH, Savanur VH, Eljarrah A, Gergues M, Kra JA, Etchegaray JP, Rameshwar P
Cancer Lett 2020 Sep 28;488:9-17. Epub 2020 May 30 doi: 10.1016/j.canlet.2020.05.026. PMID: 32479768
Khosravi A, Shahrabi S, Shahjahani M, Saki N
Cell Oncol (Dordr) 2015 Aug;38(4):253-63. Epub 2015 Jun 11 doi: 10.1007/s13402-015-0232-x. PMID: 26063518

Therapy

Tanaka TN, Bejar R
Blood 2019 Mar 7;133(10):1086-1095. Epub 2019 Jan 22 doi: 10.1182/blood-2018-10-844670. PMID: 30670443
Vrábel D, Pour L, Ševčíková S
Blood Rev 2019 Mar;34:56-66. Epub 2018 Nov 23 doi: 10.1016/j.blre.2018.11.003. PMID: 30501907
Jeong SY, Kim SJ, Pak K, Lee SW, Ahn BC, Lee J
Medicine (Baltimore) 2018 Oct;97(43):e12859. doi: 10.1097/MD.0000000000012859. PMID: 30412079Free PMC Article
Deshantri AK, Varela Moreira A, Ecker V, Mandhane SN, Schiffelers RM, Buchner M, Fens MHAM
J Control Release 2018 Oct 10;287:194-215. Epub 2018 Aug 28 doi: 10.1016/j.jconrel.2018.08.034. PMID: 30165140
Falini B, Mecucci C, Tiacci E, Alcalay M, Rosati R, Pasqualucci L, La Starza R, Diverio D, Colombo E, Santucci A, Bigerna B, Pacini R, Pucciarini A, Liso A, Vignetti M, Fazi P, Meani N, Pettirossi V, Saglio G, Mandelli F, Lo-Coco F, Pelicci PG, Martelli MF; GIMEMA Acute Leukemia Working Party
N Engl J Med 2005 Jan 20;352(3):254-66. doi: 10.1056/NEJMoa041974. PMID: 15659725

Prognosis

Yip RKH, Rimes JS, Capaldo BD, Vaillant F, Mouchemore KA, Pal B, Chen Y, Surgenor E, Murphy AJ, Anderson RL, Smyth GK, Lindeman GJ, Hawkins ED, Visvader JE
Nat Commun 2021 Nov 26;12(1):6920. doi: 10.1038/s41467-021-26556-6. PMID: 34836954Free PMC Article
Ferrer A, Roser CT, El-Far MH, Savanur VH, Eljarrah A, Gergues M, Kra JA, Etchegaray JP, Rameshwar P
Cancer Lett 2020 Sep 28;488:9-17. Epub 2020 May 30 doi: 10.1016/j.canlet.2020.05.026. PMID: 32479768
Clements ME, Johnson RW
Curr Osteoporos Rep 2019 Oct;17(5):353-361. doi: 10.1007/s11914-019-00532-y. PMID: 31468498Free PMC Article
Gillani S, Abbas Z
J Ayub Med Coll Abbottabad 2017 Apr-Jun;29(2):350-352. PMID: 28718264
Khosravi A, Shahrabi S, Shahjahani M, Saki N
Cell Oncol (Dordr) 2015 Aug;38(4):253-63. Epub 2015 Jun 11 doi: 10.1007/s13402-015-0232-x. PMID: 26063518

Clinical prediction guides

Ekmekci S, Ince D, Olgun N, Ozer E
Turk Patoloji Derg 2022;38(2):99-105. doi: 10.5146/tjpath.2021.01556. PMID: 34558657Free PMC Article
Gillani S, Abbas Z
J Ayub Med Coll Abbottabad 2017 Apr-Jun;29(2):350-352. PMID: 28718264
Cheson BD, Fisher RI, Barrington SF, Cavalli F, Schwartz LH, Zucca E, Lister TA; Alliance, Australasian Leukaemia and Lymphoma Group; Eastern Cooperative Oncology Group; European Mantle Cell Lymphoma Consortium; Italian Lymphoma Foundation; European Organisation for Research; Treatment of Cancer/Dutch Hemato-Oncology Group; Grupo Español de Médula Ósea; German High-Grade Lymphoma Study Group; German Hodgkin's Study Group; Japanese Lymphorra Study Group; Lymphoma Study Association; NCIC Clinical Trials Group; Nordic Lymphoma Study Group; Southwest Oncology Group; United Kingdom National Cancer Research Institute
J Clin Oncol 2014 Sep 20;32(27):3059-68. doi: 10.1200/JCO.2013.54.8800. PMID: 25113753Free PMC Article
Zhao E, Xu H, Wang L, Kryczek I, Wu K, Hu Y, Wang G, Zou W
Cell Mol Immunol 2012 Jan;9(1):11-9. Epub 2011 Oct 24 doi: 10.1038/cmi.2011.47. PMID: 22020068Free PMC Article
Falini B, Mecucci C, Tiacci E, Alcalay M, Rosati R, Pasqualucci L, La Starza R, Diverio D, Colombo E, Santucci A, Bigerna B, Pacini R, Pucciarini A, Liso A, Vignetti M, Fazi P, Meani N, Pettirossi V, Saglio G, Mandelli F, Lo-Coco F, Pelicci PG, Martelli MF; GIMEMA Acute Leukemia Working Party
N Engl J Med 2005 Jan 20;352(3):254-66. doi: 10.1056/NEJMoa041974. PMID: 15659725

Recent systematic reviews

Schutte T, Embaby A, Steeghs N, van der Mierden S, van Driel W, Rijlaarsdam M, Huitema A, Opdam F
Cancer Treat Rev 2023 Apr;115:102531. Epub 2023 Mar 3 doi: 10.1016/j.ctrv.2023.102531. PMID: 36893690
Łabędź W, Przybyla A, Zimna A, Dąbrowski M, Kubaszewski Ł
Int J Mol Sci 2023 Feb 14;24(4) doi: 10.3390/ijms24043785. PMID: 36835198Free PMC Article
Chan WK, Lin NS, Tay KV, Teo LT
ANZ J Surg 2023 May;93(5):1169-1175. Epub 2023 Feb 11 doi: 10.1111/ans.18324. PMID: 36772885
Zhou P, Zhang Y, Luo S, Zhang S
Radiother Oncol 2021 Dec;165:103-118. Epub 2021 Oct 27 doi: 10.1016/j.radonc.2021.10.015. PMID: 34718055
Osorio M, Moubayed SP, Su H, Urken ML
Head Neck 2017 Apr;39(4):812-818. Epub 2017 Jan 11 doi: 10.1002/hed.24655. PMID: 28079945

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