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Keratosis

MedGen UID:
9625
Concept ID:
C0022593
Disease or Syndrome
Synonym: Keratoses
SNOMED CT: Keratosis (254666005); Hyperkeratosis (254666005)
 
Monarch Initiative: MONDO:0006566

Definition

Excessive growth of keratin on the skin. [from NCI]

Professional guidelines

PubMed

Kodali N, Patel VM, Schwartz RA
Ital J Dermatol Venerol 2023 Jun;158(3):217-223. Epub 2023 May 11 doi: 10.23736/S2784-8671.23.07594-1. PMID: 37166753
Maghfour J, Ly S, Haidari W, Taylor SL, Feldman SR
J Dermatolog Treat 2022 May;33(3):1231-1242. Epub 2020 Sep 14 doi: 10.1080/09546634.2020.1818678. PMID: 32886029
Marçon CR, Maia M
An Bras Dermatol 2019 Sep-Oct;94(5):503-520. Epub 2019 Sep 30 doi: 10.1016/j.abd.2019.09.023. PMID: 31777350Free PMC Article

Recent clinical studies

Etiology

Hyeraci M, Papanikolau ES, Grimaldi M, Ricci F, Pallotta S, Monetta R, Minafò YA, Di Lella G, Galdo G, Abeni D, Fania L, Dellambra E
Biomolecules 2023 Jul 2;13(7) doi: 10.3390/biom13071067. PMID: 37509103Free PMC Article
Worley B, Harikumar V, Reynolds K, Dirr MA, Christensen RE, Anvery N, Yi MD, Poon E, Alam M
Arch Dermatol Res 2023 Jul;315(5):1099-1108. Epub 2022 Dec 1 doi: 10.1007/s00403-022-02490-5. PMID: 36454335
Eisen DB, Asgari MM, Bennett DD, Connolly SM, Dellavalle RP, Freeman EE, Goldenberg G, Leffell DJ, Peschin S, Sligh JE, Wu PA, Frazer-Green L, Malik S, Schlesinger TE
J Am Acad Dermatol 2021 Oct;85(4):e209-e233. Epub 2021 Apr 2 doi: 10.1016/j.jaad.2021.02.082. PMID: 33820677
Reinehr CPH, Bakos RM
An Bras Dermatol 2019 Nov-Dec;94(6):637-657. Epub 2019 Nov 6 doi: 10.1016/j.abd.2019.10.004. PMID: 31789244Free PMC Article
Ridley CM
Dermatol Clin 1992 Apr;10(2):309-23. PMID: 1606762

Diagnosis

Drivenes JL, Vasilescu IC, Bygum A
Tidsskr Nor Laegeforen 2023 Mar 28;143(5) Epub 2023 Mar 7 doi: 10.4045/tidsskr.22.0513. PMID: 36987905
Barthelmann S, Butsch F, Lang BM, Stege H, Großmann B, Schepler H, Grabbe S
J Dtsch Dermatol Ges 2023 Mar;21(3):265-277. Epub 2023 Mar 9 doi: 10.1111/ddg.14984. PMID: 36892019
Reinehr CPH, Bakos RM
An Bras Dermatol 2019 Nov-Dec;94(6):637-657. Epub 2019 Nov 6 doi: 10.1016/j.abd.2019.10.004. PMID: 31789244Free PMC Article
Wollina U
F1000Res 2019;8 Epub 2019 Aug 28 doi: 10.12688/f1000research.18983.1. PMID: 31508199Free PMC Article
Müller S
Head Neck Pathol 2019 Mar;13(1):16-24. Epub 2019 Jan 22 doi: 10.1007/s12105-018-0986-3. PMID: 30671762Free PMC Article

Therapy

Allen NC, Martin AJ, Snaidr VA, Eggins R, Chong AH, Fernandéz-Peñas P, Gin D, Sidhu S, Paddon VL, Banney LA, Lim A, Upjohn E, Schaider H, Ganhewa AD, Nguyen J, McKenzie CA, Prakash S, McLean C, Lochhead A, Ibbetson J, Dettrick A, Landgren A, Allnutt KJ, Allison C, Davenport RB, Mumford BP, Wong B, Stagg B, Tedman A, Gribbin H, Edwards HA, De Rosa N, Stewart T, Doolan BJ, Kok Y, Simpson K, Low ZM, Kovitwanichkanont T, Scolyer RA, Dhillon HM, Vardy JL, Chadban SJ, Bowen DG, Chen AC, Damian DL
N Engl J Med 2023 Mar 2;388(9):804-812. doi: 10.1056/NEJMoa2203086. PMID: 36856616
Nikas IP, Paschou SA, Ryu HS
Biomolecules 2020 Mar 20;10(3) doi: 10.3390/biom10030477. PMID: 32245130Free PMC Article
Snaidr VA, Damian DL, Halliday GM
Exp Dermatol 2019 Feb;28 Suppl 1:15-22. doi: 10.1111/exd.13819. PMID: 30698874
Mahmoudi K, Garvey KL, Bouras A, Cramer G, Stepp H, Jesu Raj JG, Bozec D, Busch TM, Hadjipanayis CG
J Neurooncol 2019 Feb;141(3):595-607. Epub 2019 Jan 18 doi: 10.1007/s11060-019-03103-4. PMID: 30659522Free PMC Article
Chen AC, Martin AJ, Choy B, Fernández-Peñas P, Dalziell RA, McKenzie CA, Scolyer RA, Dhillon HM, Vardy JL, Kricker A, St George G, Chinniah N, Halliday GM, Damian DL
N Engl J Med 2015 Oct 22;373(17):1618-26. doi: 10.1056/NEJMoa1506197. PMID: 26488693

Prognosis

Willenbrink TJ, Ruiz ES, Cornejo CM, Schmults CD, Arron ST, Jambusaria-Pahlajani A
J Am Acad Dermatol 2020 Sep;83(3):709-717. Epub 2020 May 7 doi: 10.1016/j.jaad.2020.03.126. PMID: 32387665
Pediatr Dermatol 2019 Nov;36(6):937-938. doi: 10.1111/pde.14062. PMID: 31778553
Jansen MHE, Kessels JPHM, Nelemans PJ, Kouloubis N, Arits AHMM, van Pelt HPA, Quaedvlieg PJF, Essers BAB, Steijlen PM, Kelleners-Smeets NWJ, Mosterd K
N Engl J Med 2019 Mar 7;380(10):935-946. doi: 10.1056/NEJMoa1811850. PMID: 30855743
Walsh SN, Hurt MA, Santa Cruz DJ
Am J Dermatopathol 2007 Apr;29(2):137-40. doi: 10.1097/01.dad.0000246177.63145.b3. PMID: 17414434
Hu W, Cook TF, Vicki GJ, Glaser DA
Pediatr Dermatol 2002 Jul-Aug;19(4):320-2. doi: 10.1046/j.1525-1470.2002.00091.x. PMID: 12220276

Clinical prediction guides

Álvarez-Salafranca M, Gómez-Martín I, Bañuls J, Serrano P, Medina C, Llambrich A, Pizarro Á, Ara M, Zaballos P
Australas J Dermatol 2022 Feb;63(1):53-61. Epub 2021 Dec 27 doi: 10.1111/ajd.13781. PMID: 34958128
Wells A, Patel S, Lee JB, Motaparthi K
J Cutan Pathol 2021 Aug;48(8):1061-1068. Epub 2021 Jan 26 doi: 10.1111/cup.13954. PMID: 33421167
Ogawa T, Donizy P, Wu CL, Cornejo KM, Ryś J, Hoang MP
Am J Dermatopathol 2020 Sep;42(9):629-640. doi: 10.1097/DAD.0000000000001548. PMID: 32833736
Cantisani C, Paolino G, Melis M, Faina V, Romaniello F, Didona D, Cardone M, Calvieri S
Recent Pat Inflamm Allergy Drug Discov 2016;10(1):40-48. doi: 10.2174/1872213x10666160504104825. PMID: 27142784
Saha KC
J Environ Sci Health A Tox Hazard Subst Environ Eng 2003 Jan;38(1):255-72. doi: 10.1081/ese-120016893. PMID: 12635831

Recent systematic reviews

Worley B, Harikumar V, Reynolds K, Dirr MA, Christensen RE, Anvery N, Yi MD, Poon E, Alam M
Arch Dermatol Res 2023 Jul;315(5):1099-1108. Epub 2022 Dec 1 doi: 10.1007/s00403-022-02490-5. PMID: 36454335
Mainville L, Smilga AS, Fortin PR
J Cutan Med Surg 2022 May-Jun;26(3):297-308. Epub 2022 Feb 8 doi: 10.1177/12034754221078201. PMID: 35134311Free PMC Article
Maghfour J, Ly S, Haidari W, Taylor SL, Feldman SR
J Dermatolog Treat 2022 May;33(3):1231-1242. Epub 2020 Sep 14 doi: 10.1080/09546634.2020.1818678. PMID: 32886029
Eisen DB, Asgari MM, Bennett DD, Connolly SM, Dellavalle RP, Freeman EE, Goldenberg G, Leffell DJ, Peschin S, Sligh JE, Wu PA, Frazer-Green L, Malik S, Schlesinger TE
J Am Acad Dermatol 2021 Oct;85(4):e209-e233. Epub 2021 Apr 2 doi: 10.1016/j.jaad.2021.02.082. PMID: 33820677
González-Moles MÁ, Warnakulasuriya S, González-Ruiz I, González-Ruiz L, Ayén Á, Lenouvel D, Ruiz-Ávila I, Ramos-García P
Oral Dis 2021 May;27(4):813-828. Epub 2020 Apr 2 doi: 10.1111/odi.13323. PMID: 32144836

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