GEO DataSets for BioProject (Select 110677) - GEO DataSets

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Items: 3

Select item 2000135761.

Early Relapse in ALL is identified by Time To Leukemia in NOD/SCID mice and is characterized by a gene signature involving survival pathways

(Submitter supplied) Gene expression analysis identified a specific signature of differentially expressed genes discriminating TTLshort and TTLlong phenotypes. Gene expression signatures of xenografted leukemia samples with different TTL phenotypes were analyzed on cohorts of pediatric BCP-ALL patients.

Organism:: Homo sapiens

Type:: Expression profiling by array

Datasets:: GDS4206 GDS4779
Platform:: GPL570
209 Samples

Download data: CEL

Series

Accession:: GSE13576

ID:: 200013576

Select item 47792.

NOD/SCID/huALL xenotransplant model of pediatric acute leukemia

Analysis of xenograft leukemia samples from NOD/SCID mice transplanted with leukemia cells from patients with pediatric BCP-ALL. The xenograft samples displayed short or long “Time To Leukemia” (TTL). Results provide insight into molecular mechanisms underlying the distinct TTL phenotypes.

Organism:: Homo sapiens

Type:: Expression profiling by array, transformed count, 2 disease state sets

Platform:: GPL570
Series:: GSE13576
12 Samples

Download data: CEL

DataSet

Accession:: GDS4779

ID:: 4779

Select item 42063.

Pediatric acute leukemia patients with early relapse: white blood cells

Analysis of WBCs from pediatric B cell precursor (BCP) acute lymphoblastic leukemia (ALL) patients with early, late, or no relapse. For patients with relapsed BCP-ALL, early relapses fare worse than later relapses. Results provide insight into the molecular basis of early relapses in BCP-ALL.