GEO DataSets for BioProject (Select 193671) - GEO DataSets

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Items: 2

Select item 2000454171.

Expression data from knockdown of ZXDC1/2 in PMA-treated U937

(Submitter supplied) ZXDC1 augments the expression of various markers of monocyte/macrophage differentiation when over-expressed in the U937 cell line treated with the phorbol ester PMA. Likewise, knockdown of ZXDC1 restricts the induced expression of these markers. We sought to identify specfic gene targets of ZXDC1 during the process of monocyte/macrophage differentiation in U937 by performing gene expression profiling in cells exhibiting reduced expression of ZXDC1 compared to controls. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS5070
Platform:: GPL570
12 Samples

Download data: CEL

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Accession:: GSE45417

ID:: 200045417

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 50702.

Zinc finger transcription factor ZXDC depletion effect on myeloid cell line undergoing differentiation

Analysis of U937 myeloid cells treated with phorbol 12-myristate 13-acetate (PMA) and depleted for the zinc finger transcription factor ZXDC. PMA treatment induces myeloid cell differentiation. Results provide insight into the role of ZXDC in myeloid cell differentiation.