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Items: 10

1.
Full record GDS5163

Hydrogen peroxide-scavenging enzymes AhpCF, KatE and KatG deficiency

Analysis of Hpx- (ahpCF::kanR, katG, katE) triple deletion mutant. H202 scavenging is performed by the three hydrogen enzymes: alkyl hydroperoxidase reductase (AhpCF), catalase G (KatG) and catalase E (KatE). Results provide insight into molecular basis of the oxidative stress response in bacteria.
Organism:
Escherichia coli; Escherichia coli str. K-12 substr. MG1655
Type:
Expression profiling by array, transformed count, 2 genotype/variation sets
Platform:
GPL3154
Series:
GSE56133
6 Samples
Download data: CEL
2.
Full record GDS5162

Gentamicin effect on fur-deficient cells

Analysis of Δfur and wildtype cells treated with the bacterial antibiotic gentamicin and harvested 1 hr post-treatment. Fur is the master regulator of iron metabolism in E. coli. Results provide insight into Fur's influence on the magnitude of stress responses triggered by bactericidal antibiotics.
Organism:
Escherichia coli; Escherichia coli str. K-12 substr. MG1655
Type:
Expression profiling by array, transformed count, 2 agent, 2 genotype/variation sets
Platform:
GPL3154
Series:
GSE56133
12 Samples
Download data: CEL
3.
Full record GDS5160

Multiple bactericidal antibiotics

Analysis of wild-type cells treated with various antibiotics or hydrogen peroxide and harvested 1 hour post-treatment. Results provide insight into the molecular mechanisms underlying antibiotic lethality.
Organism:
Escherichia coli; Escherichia coli str. K-12 substr. MG1655
Type:
Expression profiling by array, transformed count, 6 agent sets
Platform:
GPL3154
Series:
GSE56133
18 Samples
Download data: CEL
4.
Full record GDS4321

Escherichia coli O157:H7 response to cinnamaldehyde: time course

Analysis of E. coli O157:H7 exposed to cinnamaldehyde (CIN) for up to 4 hours. CIN is a natural antimicrobial effective against many foodborne pathogens including Escherichia coli O157:H7. Results provide insight into molecular processes underlying CIN-induced transient inhibition of E. coli.
Organism:
Escherichia coli; Escherichia coli O157:H7
Type:
Expression profiling by array, transformed count, 2 agent, 2 time sets
Platform:
GPL3154
Series:
GSE40693
8 Samples
Download data: CEL
5.
Full record GDS4815

Escherichia coli response to the arylamide compound PMX 10070: time course

Analysis of Escherichia coli cells treated with a sublethal concentration of the antimicrobial arylamide compound PMX 10070 for 20 and 60 minutes. Arylamides permeabilize E. coli membranes. Results provide insight into molecular mechanisms underlying the antibacterial action of arylamides.
Organism:
Escherichia coli
Type:
Expression profiling by array, count, 3 agent, 2 time sets
Platform:
GPL3154
Series:
GSE31140
18 Samples
Download data: CEL, CHP
6.
Full record GDS3597

Increased cell membrane saturated fatty acid effect on Escherichia coli

Analysis of Escherichia coli cells treated with CHIR-090, an inhibitor of lipid A bioynthesis, to increase the ratio of saturated to unsaturated fatty acids (SFA:UFA) in the cell membrane. Results provide insight into molecular mechanisms regulating membrane lipid homeostasis in E. coli.
Organism:
Escherichia coli
Type:
Expression profiling by array, count, 2 agent sets
Platform:
GPL3154
Series:
GSE18623
6 Samples
Download data: CEL
7.
Full record GDS3421

Frag1 cells response to ionic and non-ionic hyperosmotic stress

Analysis of bacterial Frag1 cells subjected to ionic (NaCl) and non-ionic (sucrose) hyperosmotic stress (HS). Results provide insight into the molecular mechanisms underlying the specificity of osmotic adjustment to ionic and non-ionic osmotica.
Organism:
Escherichia coli
Type:
Expression profiling by array, count, 3 stress sets
Platform:
GPL3154
Series:
GSE12190
6 Samples
Download data: CEL, CHP
DataSet
Accession:
GDS3421
ID:
3421
8.
Full record GDS2879

Enterohemorrhagic Escherichia coli response to epinephrine, norepinephrine, and indole

Analysis of enterohemmorhagic Escherichia coli (EHEC) O157:H7 treated with epinephrine (EP), norepinephrine (NE), and indole. During infection in the gastrointestinal tract, EHEC is exposed to a wide range of signaling molecules such as EP and NE, and bacterial signaling molecules such as indole.
Organism:
Escherichia coli
Type:
Expression profiling by array, count, 4 agent sets
Platform:
GPL3154
Series:
GSE5552
4 Samples
Download data: CEL, RPT
9.
Full record GDS2753

Enterohemorrhagic Escherichia coli biofilm response to 7-hydroxyindole and isatin

Analysis of enterohemorrhagic Escherichia coli biofilm treated with 7-hydroxyindole or oxidized indole (isatin). Many bacterial oxygenases readily convert indole, an interspecies biofilm signal, into oxidized compounds. Results provide insight into the role of oxidized indoles in biofilm formation.
Organism:
Escherichia coli
Type:
Expression profiling by array, count, 3 agent, 2 cell type sets
Platform:
GPL3154
Series:
GSE6195
4 Samples
Download data: CEL
10.
Full record GDS2427

Arginine regulon repression and derepression

Analysis of cells with the arginine (Arg) regulon fully or partially repressed, or derepressed. Genes of the Arg regulon are coordinately repressed by the Arg repressor (ArgR) in response to Arg. Results provide insight into ArgR-mediated repression of arginine biosynthesis and uptake genes.
Organism:
Escherichia coli
Type:
Expression profiling by array, count, 2 genotype/variation, 2 growth protocol, 3 other sets
Platform:
GPL3154
Series:
GSE4724
9 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS2427
ID:
2427
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