GEO DataSets

Analysis of cultured cortical neurons treated with 1uM lactacystin for up to 48 hr. Lactacystin induces neuronal apoptosis. Results provide insight into molecular mechanisms underlying proteasomal inhibition-induced neuronal death.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 agent, 2 time sets

Platform:

GPL32

Series:

GSE22465

4 Samples

Download data: CEL

Analysis of substantia nigrae (SN) injured by treatment with the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine at 1 and 7 days postlesion. Parkinson's disease (PD) culminates in the loss of dopaminergic neurons of the SN. Results provide insight into the pathogenesis of PD.

Organism:

Mus musculus

Type:

Expression profiling by array, transformed count, 2 agent, 3 time sets

Platform:

GPL32

Series:

GSE4788

12 Samples

Download data: CEL

Analysis of embryonic stem cells differentiated in the presence of PD169316, an inhibitor of p38 that blocks apoptosis without altering differentiation. Results identify gene families whose transcriptional regulation correlates with cell fate: differentiation with or without apoptosis.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 agent, 2 cell line sets

Platform:

GPL32

Series:

GSE2042

6 Samples

Download data: CEL, EXP

Analysis of liver of 6 week old stearoyl-CoA desaturase 1 (SCD1) knockout females. SCD1 is a lipogenic enzyme that catalyzes the synthesis of monosaturated fatty acids. SCD1 null mutants have reduced body adiposity, increased insulin sensitivity, and are resistant to diet-induced weight gain.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL32

Series:

GSE2926

10 Samples

Download data: CEL, EXP

Expression profiling of embryonic stem (ES) cells following stimulation with fetal bovine serum at various time points up to 180 minutes. Expression in wild type ES cells compared to that in Srf homozygous mutants with or without an SRF transgene. Results identify potential targets of SRF.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 genotype/variation, 2 protocol, 5 time sets

Platform:

GPL32

Series:

GSE1949

15 Samples

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Expression profiling of embryonic stem (ES) cells overexpressing serum response factor SRF. SRF transiently transfected into ES cells disrupted for both copies of SRF. RNA examined 72 hours after transfection. Results identify potential transcriptional targets of SRF.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 agent, 4 genotype/variation sets

Platform:

GPL32

Series:

GSE1948

23 Samples

Download data

Analysis of dendritic cell (DC) development from Flt3(+)CD11b(+) DC progenitors. DC progenitors treated with GM-CSF for 7 and 10 days to induce differentiation. DCs differentiated for 10 days were subsequently treated with TNFalpha to induce maturation.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 4 protocol sets

Platform:

GPL32

Series:

GSE575

4 Samples

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Analysis of extraocular (EOM) and hindlimb (gastrocnemius/soleus) muscle in mdx (dystrophin-deficient; Duchenne muscular dystrophy model) mice at postnatal day 56.5. Highly specific changes observed between dystrophic (leg) and spared (EOM) muscle.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 strain, 2 tissue sets

Platform:

GPL32

Series:

GSE1472

20 Samples

Download data: CEL

Comparison of extraocular (EOM), masticatory (masseter), and hindlimb (gastrocnemius/soleus) muscle in 8 week old mice. EOM defined by distinct gene expression profile.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 tissue sets

Platform:

GPL32

Series:

GSE1062

14 Samples

Download data: CEL

Examination of ventricles of 10 week mice overexpressing dominant-negative (dn) small GTP binding protein p21ras. dn-p21ras mice show severe cardiac dilation and decreased contractility. p21ras implicated in hypertrophic response of cardiomyocytes.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 genotype/variation sets

Platform:

GPL32

Series:

GSE760

6 Samples

Download data: CEL

Identification of new targets of major histocompatibility complex class II transactivator CIITA in dendritic cells (DC). Day 10 bone marrow-derived DCs isolated from B6 background CIITA-deficient, MHC class II-deficient and wild type mice examined.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 3 strain sets

Platform:

GPL32

Series:

GSE557

3 Samples

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Cardiotoxin injected into mouse gastrocnemius muscle to induce muscle regeneration. Muscles profiled at 27 time points (0-40 days) post-injection. Transcriptional regulatory pathways defined.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 6 time sets

Platform:

GPL32

Series:

GSE469

12 Samples

Download data: CEL

Gene expression profiles from a diverse array of tissues, organs, and cell lines, from the normal physiological state. Represents a preliminary description of the normal mammalian transcriptome.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 45 tissue sets

Platform:

GPL32

Series:

GSE97

90 Samples

Download data: CEL

Benchmark gene expression profile of heart ventricle at various ages to monitor changes in cardiac development. Examined embryonic stages through adolescence and adulthood.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 7 development stage, 3 gender sets

Platform:

GPL32

Series:

GSE75

24 Samples

Download data: CEL