GEO DataSets

(Submitter supplied) Bats harbor highly virulent viruses that can infect other mammals, including humans, posing questions about their immune tolerance mechanisms. Bat cells employ multiple strategies to limit virus replication and virus-induced immunopathology, but the coexistence of bats and fatal viruses remains poorly understood. Here, we investigated the antiviral RNA interference (RNAi) pathway in bat cells and discovered that they have an enhanced antiviral RNAi response, producing canonical viral small interfering RNAs (vsiRNAs) upon Sindbis virus (SINV) infection that were missing in human cells. more...

Organism:

Pteropus alecto; Tadarida brasiliensis; Homo sapiens

Type:

Non-coding RNA profiling by high throughput sequencing

Platforms:

GPL11154 GPL15898 GPL34381

12 Samples

Download data: XLS

(Submitter supplied) Deep sequencing of mRNA from Pteropus alecto and Myotis davidii

Organism:

Myotis davidii; Pteropus alecto

Type:

Expression profiling by high throughput sequencing

Platforms:

GPL16126 GPL15898

2 Samples

Download data: FA, WIG